Thursday November 14, 2019

Scientists Develop Potential Approach to Treat Dementia, Stroke

"It also shows that these changes may be reversible, paving the way for potential treatments," Williams added

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The article provides information on the topic "Scientists Develop Potential Approach to Treat Dementia, Stroke". (IANS)

Stopping blood vessel cells from becoming dysfunctional may reverse the symptoms of small vessel disease (SVD) — major cause of dementia and stroke — and prevent brain damage in older adults, scientists have found.

The study, led by the University of Edinburgh, found that SVD occurs when cells that line the small blood vessels in the brain become dysfunctional causing them to secrete a molecule into the brain.

The molecule stops production of the protective layer that surrounds brain cells — called myelin — leading to brain damage.

“This important research helps us understand why small vessel disease happens, providing a direct link between small blood vessels and changes in the brain that are linked to dementia,” said Anna Williams from University of Edinburgh’s MRC Centre for Regenerative Medicine in Scotland.

“It also shows that these changes may be reversible, paving the way for potential treatments,” Williams added.

1 in 6 people over the age of 80 have dementia. Pixabay
1 in 6 people over the age of 80 have dementia. Pixabay

In the study, published in the journal Science Translational Medicine, the team used rat model and found that treating them with drugs that can reverse changes in blood vessels in the brain associated with cerebral small vessel disease.

“The findings highlight a promising direction for research into treatments that could limit the damaging effects of blood vessel changes and help keep nerve cells functioning for longer,” said Sara Imarisio, Head of Research at Alzheimer’s Research in Britain.

Also Read: Sleep Disorder Linked with Brain Changes Found in Dementia

However, further studies are needed to test whether the treatment also works when the disease is firmly established, researchers said.

Dementia is one of the biggest problems facing society, as people live longer and the population ages.

Estimates indicate there are almost 47 million people living with dementia worldwide and the numbers affected are expected to double every 20 years, rising to more than 115 million by 2050. (IANS)

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Scientists: Nations Need Stronger Pledges to Curb Climate Change

Governments are moving in the right direction, but nowhere near enough, so hopefully they will be willing to take on much stronger commitments

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Scientists, Nations, Climate Change
A woman wearing a mask walks past buildings on a polluted day in Handan, Hebei province, China, Jan. 12, 2019. China is reportedly the world's top emitter of greenhouse gases. VOA

The vast majority of national commitments in the 2015 Paris Agreement are inadequate to prevent the worst effects of global warming, scientists said on Tuesday, naming the world’s biggest greenhouse gas emitting countries as among those that must ratchet up their efforts.

“Governments are moving in the right direction, but nowhere near enough, so hopefully they will be willing to take on much stronger commitments” in next month’s United Nation’s climate summit in Spain, said Robert Watson, lead author of the report by the nonprofit Universal Ecological Fund.

The report ranked nearly 75%, or 136, of the pledges as insufficient, including ones by major carbon emitters China, the United States, and India. A dozen, by countries including Australia, Japan and Brazil, were judged only partially sufficient.

Countries at next month’s summit in Madrid will hash out some details of the international pact to curb warming. Chile withdrew as host following weeks of riots protesting inequality.

Scientists, Nations, Climate Change
A protestor holds a placard in front of the India Gate during a protest demanding government to take immediate steps to control air pollution in New Delhi, India, Nov. 5, 2019. VOA

Of the 184 pledges countries made under the climate agreement, only 36 are ambitious enough to help reach the agreement’s goal of keeping global warming less than 1.5 Celsius (2.7 F) above pre-industrial levels, the report said.

Most of those 36 are by countries in the European Union.

Watson, a former chair of the U.N. Intergovernmental Panel on Climate Change, said the report could be read two ways: “You can read ‘My God it’s hopeless’, or ‘My God this is a wake up call.'”

Watson estimated that even if all nations meet their existing pledges, the world would be headed for temperature rise of between 3 and 3.5 degrees Celsius, which could lead to more extreme weather, rising sea levels and the loss of plant and animal species.

Also Read- New WhatsApp Feature Lets Users Decide to Join a Group or Not: Tech Report

The report rated the European Union’s 28 member states as having sufficient pledges because they aim to cut emissions of greenhouse gases by at least 40% below the 1990 level by 2030.

It ranked the United States as insufficient because President Donald Trump reversed former President Barack Obama’s climate policies and yanked Washington out of the pact. The administration, which argues that Paris Agreement would cost U.S. taxpayers too much money, filed official paperwork on Monday to withdraw.

China, the world’s top emitter of greenhouse gases, and India, also came in as insufficient because their pledges focus on carbon intensity targets, which lower emissions per unit of gross domestic product, or GDP. Because those economies are growing and coal produces much of their electricity, total emissions have risen sharply even though carbon intensity levels in China and India have fallen. (VOA)