Thursday November 21, 2019

Now Comes a Shoe Insole That Could Treat Foot Ulcers Caused Due to Diabetes

A patent is pending on the insole technology. The team is currently seeking corporate partners

0
//
The findings, published in the journal Diabetologia, were based on data from nearly 2,800 children with a first-degree relative with Type-1 diabetes.
New shoe insole could treat diabetic foot ulcers. Pixabay

Researchers have developed a shoe insole that could help make the healing process more portable for people who develop ulcers as a result of diabetes.

Diabetic ulcers commonly result from high blood sugar damaging nerves, which takes away feeling from the toes or feet.

“One of the ways to heal these wounds is by giving them oxygen,” said Babak Ziaie, Professor at the Purdue University in the US.

“We’ve created a system that gradually releases oxygen throughout the day so that a patient can have more mobility.”

Without the ability to feel pain, hits and bumps tend to go unnoticed and skin tissue breaks down, forming ulcers.

A lot of sugar in the bloodstream, along with dried skin as a result of diabetes, further slow the ulcer healing process.

The researchers used lasers to shape silicone-based rubber into insoles, and then create reservoirs that release oxygen only at the part of the foot where the ulcer is located.

Diabetes
Representational image. Pixabay

“Silicone is flexible and has good oxygen permeability,” said Hongjie Jiang, a post-doctoral researcher at the varsity.

“Laser machining helps us to tune that permeability and target just the wound site, which is hypoxic, rather than poison the rest of the foot with too much oxygen,” Jiang added.

In a paper published in the journal Materials Research Society Communications, the team said the insole can deliver oxygen at least eight hours a day under the pressure of someone weighing about 53-81 kg.

It can also be customised to take on any weight, the study said.

Also Read- Facebook Investors Increase Pressure on CEO Mark Zuckerberg To Step Down

The team envisions a manufacturer sending a patient a pack of pre-filled insoles customised to his or her wound site, based on a “wound profile” obtained from a doctor’s prescription and a picture of the foot.

“This is mass-customisation at low cost,” said Vaibhav Jain, research associate at Purdue.

A patent is pending on the insole technology. The team is currently seeking corporate partners. (IANS)

Next Story

Study Says, Early Signs of Diabetes Can be Observed in Children

The study tracked over 4,000 participants of the Children of the 90s study, a birth cohort established in Bristol in the early 1990s

0
Diabetes
The research was conducted among young healthy people who were generally free of type 2 Diabetes and other chronic diseases to see how early in life the effects of diabetes susceptibility become visible. Pixabay

Researchers have found that early signs of adulthood type 2 Diabetes can be seen in children as young as 8 years old.

Type 2 diabetes is most often diagnosed in middle age or later, with its symptoms slowly developing over many years.

“It’s remarkable that we can see signs of adult diabetes in the blood from such a young age, this is about 50 years before it’s commonly diagnosed.

“This is not a clinical study; nearly all participants were free of diabetes and most will not go on to develop it. This is about liability to disease and how genetics can tell us something about how the disease develops,” said study researcher Joshua Bell from the University of Bristol in the UK.

The research was conducted among young healthy people who were generally free of type 2 diabetes and other chronic diseases to see how early in life the effects of diabetes susceptibility become visible.

The study tracked over 4,000 participants of the Children of the 90s study, a birth cohort established in Bristol in the early 1990s.

The researchers combined genetics with an approach called ‘metabolomics’, which involves measuring many small molecules in a blood sample to try and identify patterns that are unique to type 2 diabetes.

According to the findings, the research team analysed 162 pieces of genetic information and combined this with 200 measures of many small molecules in a blood sample, known as metabolics, to identify signs of type 2 diabetes.

Diabetes
Researchers have found that early signs of adulthood type 2 Diabetes can be seen in children as young as 8 years old. Pixabay

Data was taken once in childhood — at 8 years old, twice in adolescence aged 16 and 18 years and once in young adulthood aged 25 years.

They found levels of HDL cholesterol were reduced at age 8, while inflammatory glycoprotein acetyls and amino acids were elevated in 16 and 18 year old teenagers.

These metabolic features could be targeted to prevent young people from going on to develop type 2 diabetes in the future, the researchers said.

ALSO READ: Income Tax Officers Quit Work For Mental Peace

The findings were presented at the European Association for the Study of Diabetes (EASD) Annual Meeting in Barcelona. (IANS)