Saturday March 23, 2019

Now Comes a Shoe Insole That Could Treat Foot Ulcers Caused Due to Diabetes

A patent is pending on the insole technology. The team is currently seeking corporate partners

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The findings, published in the journal Diabetologia, were based on data from nearly 2,800 children with a first-degree relative with Type-1 diabetes.
New shoe insole could treat diabetic foot ulcers. Pixabay

Researchers have developed a shoe insole that could help make the healing process more portable for people who develop ulcers as a result of diabetes.

Diabetic ulcers commonly result from high blood sugar damaging nerves, which takes away feeling from the toes or feet.

“One of the ways to heal these wounds is by giving them oxygen,” said Babak Ziaie, Professor at the Purdue University in the US.

“We’ve created a system that gradually releases oxygen throughout the day so that a patient can have more mobility.”

Without the ability to feel pain, hits and bumps tend to go unnoticed and skin tissue breaks down, forming ulcers.

A lot of sugar in the bloodstream, along with dried skin as a result of diabetes, further slow the ulcer healing process.

The researchers used lasers to shape silicone-based rubber into insoles, and then create reservoirs that release oxygen only at the part of the foot where the ulcer is located.

Diabetes
Representational image. Pixabay

“Silicone is flexible and has good oxygen permeability,” said Hongjie Jiang, a post-doctoral researcher at the varsity.

“Laser machining helps us to tune that permeability and target just the wound site, which is hypoxic, rather than poison the rest of the foot with too much oxygen,” Jiang added.

In a paper published in the journal Materials Research Society Communications, the team said the insole can deliver oxygen at least eight hours a day under the pressure of someone weighing about 53-81 kg.

It can also be customised to take on any weight, the study said.

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The team envisions a manufacturer sending a patient a pack of pre-filled insoles customised to his or her wound site, based on a “wound profile” obtained from a doctor’s prescription and a picture of the foot.

“This is mass-customisation at low cost,” said Vaibhav Jain, research associate at Purdue.

A patent is pending on the insole technology. The team is currently seeking corporate partners. (IANS)

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Cardiovascular Events Cause 58% Deaths Among Diabetics

The medicine likewise helps lower the amount of sodium in the body and reduce triglyceride levels and blood pressure

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Diabetes
Representational image. Pixabay

Fifty-eight percent of deaths among people with type 2 diabetes are due to cardiovascular events, a leading Mexican expert has said.

“Patients who live with this disease have a greater risk of premature death or disability derived from cardiovascular events,” Hector Sanchez Mijangos, President of the Mexican Diabetes Federation, told Efe news.

The specialist said that the high glucose levels associated with diabetes damage blood vessels, resulting in problems with blood pressure and vision, joint pain and other maladies.

Data from the World Health Organization indicate that more 442 million people suffer from type 2 diabetes.

Mexico’s Health Secretariat has found that while roughly 13 million inhabitants of the Aztec nation are living with diabetes, only half of those afflicted know they have the disease.

In 2015 alone, according to Mijangos, there were more than 98,000 premature deaths in Mexico related to diabetes and the average age of those who died was 66.7 years old.

Diabetes
Representational image. Pixabay

“This is regrettable, because these people could have lived roughly another 15 years,” he said.

According to the 2012 National Health and Nutrition Survey, only 25 percent of Mexicans suffering with diabetes are managing their condition adequately.

That figure illustrates “why our greatest challenge continues to be access and adherence to treatment”, Mijangos said.

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To improve treatment options, Mexican health authorities in January issued an approval for the use of canagliflozin, a drug that helps reduce the amount of blood glucose reabsorbed by the kidneys, which in turns causes more glucose to be eliminated through urination.

“With this medicine, a person can lose 100 milligrams of glucose per day as well as about 400 kilocalories (4,000 calories) a day, which also helps with weight loss,” Mijangos said.

The medicine likewise helps lower the amount of sodium in the body and reduce triglyceride levels and blood pressure.

A scientific trial involving more than 10,000 patients worldwide showed that when combined with conventional treatment, canagliflozin can reduce the incidence of cardiovascular events by up to 18 percent. (IANS)