Friday February 21, 2020

Even Short-term ‘Vaping’ can Cause Inflammation, Says Study

With the recent reports of lung disease and deaths associated with vaping, the effects of vaping nicotine and marijuana oils makes this research more critical, said the researchers

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US, CDC, Vaping
FILE - A high school student uses a vaping device near the school's campus in Cambridge, Mass., April 11, 2018. VOA

E-cigarette use has risen at concerning levels among both smokers and non-smokers and now researchers from the Ohio State University have found that even short-term vaping could cause cellular inflammation in never-smoker adults.

Using a procedure called bronchoscopy to test for inflammation and smoking-related effects, researchers reported a measurable increase in inflammation after four weeks of e-cigarette use without nicotine or flavours.

The study suggested that even short-term usage could result in inflammatory changes at a cellular level.

“Through the randomised clinical trial of healthy never-smokers over a month, we found that an increase in urinary propylene glycol, a marker of inhalation-e-cig intake, was significantly correlated with increased inflammatory response in the lung,” said the study’s first author Min-Ae Song from Ohio State University.

For the study, researchers recruited 30 healthy, non-smoking volunteers to directly assess the impact of tobacco and e-cig use on the lungs through bronchoscopy, an outpatient test in which a doctor inserts a thin tube through the nose or mouth to view the airways.

Vaping, teeth,e-cigarette, cigarettes
Nicotine vaping on rise among US teenagers: Survey. Pixabay

A small sample of lung cells was collected from fluid in the lungs.

Participants were randomised to a four-week intervention with e-cigs containing only 50 per cent propylene glycol (PG) or 50 per cent vegetable glycerine (VG) without nicotine or flavours.

Results from these tests were then compared to a separate control group of never-smokers.

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Researchers did not see levels of inflammation higher than the controls, but there was an increase in inflammation among the users who inhaled more of the e-cigarette.

With the recent reports of lung disease and deaths associated with vaping, the effects of vaping nicotine and marijuana oils makes this research more critical, said the researchers. (IANS)

Next Story

Find out How Optimism Can Help Reduce Stroke Severity

Optimism can reduce stroke severity, inflammation

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Optimism Stroke
Stroke survivors with high levels of optimism had lower inflammation levels, reduced stroke severity and less physical disability after three months. Pixabay

Researchers have found that stroke survivors with high levels of optimism had lower inflammation levels, reduced stroke severity and less physical disability after three months, compared to those who are less optimistic.

“Our results suggest that optimistic people have a better disease outcome, thus boosting morale may be an ideal way to improve mental health and recovery after a stroke,” said study senior author Yun-Ju Lai from University of Texas in the US.

In a small study of 49 stroke survivors, researchers examined the relationship among optimism, inflammation, stroke severity and physical disability for three months after an attack.

Researchers said that understanding how these elements relate to, or impact one another, may provide a scientific framework to develop new strategies for stroke recovery.

Optimism Stroke
Optimism has been associated with lower inflammation levels and improved health outcomes among people with medical conditions. Pixabay

Post-stroke inflammation is detrimental to the brain and impairs recovery, the researchers said.

Optimism has been associated with lower inflammation levels and improved health outcomes among people with medical conditions. However, no prior studies have assessed if this association exists among stroke patients.

This pilot study is a secondary analysis of data collected from a repository of neurological diseases.

Outcomes included optimism levels from the revised Life Orientation Test, a standard psychological tool for measuring optimism; stroke severity evaluation through the National Institutes of Health Stroke Scale, and levels of inflammatory markers–interleukin-6 (IL-6), tumour necrosis factor alpha (TNFa) and C-reactive protein (CRP).

As optimism levels increased, stroke severity and the inflammatory markers IL-6 and CRP decreased even after considering other possible variables. However, this was not true of TNFa.

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“Patients and their families should know the importance of a positive environment that could benefit the patient, mental health does affect recovery after a stroke,” Lai said.

The study is scheduled to be presented at the American Stroke Association’s International Stroke Conference slated from February 18 to 21 in the US. (IANS)