Tuesday September 25, 2018

A new type of skin patch that may reduce body: study

0
//
64
A new type of skin patch that may reduce body: study
A new type of skin patch that may reduce body: study. wikimedia commons
Republish
Reprint

Singapore, Dec 29, 2017: Researchers have developed a new type of skin patch that may reduce body fat and obesity by turning energy-storing white fat into energy-burning brown fat. According to the researchers, brown fats are found in babies and they help to keep the baby warm by burning energy. As humans grow older, the amount of brown fat lessens and is replaced with visceral white fats.

“What we aim to develop is a painless patch that everyone could use easily, is unobtrusive and yet affordable. Most importantly, our solution aims to use a person’s own body fats to burn more energy, which is a natural process in babies,” said Chen Peng, professor at Nanyang Technological University (NTU), Singapore.

The new type of skin patch contains hundreds of micro-needles which are loaded with the drug Beta-3 adrenergic receptor agonist or another drug called thyroid hormone T3 triiodothyronine.

When the patch is pressed into the skin for about two minutes, these micro-needles become embedded in the skin and detach from the patch, which can then be removed.

As the needles degrade, the drug molecules then slowly diffuse to the energy-storing white fat underneath the skin layer, turning them into energy-burning brown fats.

Published in the journal Small Methods, this approach could help to address the worldwide obesity problem without resorting to surgical operations or oral medications. In a laboratory experiments conducted by the researchers showed that the patch could suppress weight gain in mice that were fed a high fat diet and reduce their fat mass by over 30 per cent, over a period of four weeks.

“With the embedded micro-needles in the skin of the mice, the surrounding fats started browning in five days, which helped to increase the energy expenditure of the mice, leading to a reduction in body fat gain,” said Xu Chenjie, assistant professor at NTU.

The treated mice also had significantly lower blood cholesterol and fatty acids levels compared to the untreated mice. (IANS)

Click here for reuse options!
Copyright 2017 NewsGram

Next Story

Exposure to Certain Disinfectants Can Cause Obesity in Kids: Research

The use of eco-friendly products may be linked to healthier overall maternal lifestyles and eating habits.

0
Disinfectants
How common household cleaners could make kids overweight. Flickr

Early life exposure to certain disinfectants used at home could be making children overweight by altering the composition of their gut bacteria, suggests new research.

Babies living in households that used eco-friendly cleaners had different microbiota and were less likely to be overweight as toddlers, showed the findings published in CMAJ (Canadian Medical Association Journal).

For the study, the researchers analysed the gut flora of 757 infants from the general population at age 3-4 months and weight at ages 1 and 3 years, looking at exposure to disinfectants, detergents and eco-friendly products used in the home.

Disinfectants
Mother’s Lifestyle Choices Linked to Obesity Risk in Adolescents. Pixabay

The researchers looked at data from the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort on microbes in infant fecal matter. They used World Health Organization growth charts for body mass index (BMI) scores.

Associations with altered gut flora in babies 3-4 months old were strongest for frequent use of household disinfectants such as multi-surface cleaners, which showed lower levels of Haemophilus and Clostridium bacteria but higher levels of Lachnospiraceae.

The researchers also observed an increase in Lachnospiraceae bacteria with more frequent cleaning with disinfectants.

They, however, did not find the same association with detergents or eco-friendly cleaners.

“We found that infants living in households with disinfectants being used at least weekly were twice as likely to have higher levels of the gut microbes Lachnospiraceae at age 3-4 months,” said Anita Kozyrskyj, Professor at the University of Alberta in Canada.

Disinfectants
The researchers looked at data from the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort on microbes in infant fecal matter. Flcikr

“When they were 3 years old, their body mass index was higher than children not exposed to heavy home use of disinfectants as an infant,” Kozyrskyj said.

“Those infants growing up in households with heavy use of eco cleaners had much lower levels of the gut microbes Enterobacteriaceae,” she said.

Also Read: Asthma Ups The Chance of Obesity: Study

Kozyrskyj suggests that the use of eco-friendly products may be linked to healthier overall maternal lifestyles and eating habits, contributing in turn to the healthier gut microbiomes and weight of their infants. (IANS)

Next Story