Wednesday June 26, 2019

Losing Just 6 Hours of Sleep May Spike up Diabetes Risk: Study

During the sleep/wake period, the animals also had limited opportunity for physical activity

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Soothing colours, right scent aid sound sleep. Pixabay

Being deprived of sleep for just six hours or a single night may affect the liver’s ability to produce glucose and process insulin, increasing the risk of metabolic diseases such as fatty liver and Type-2 diabetes, warns a study.

Sleep deprivation has been associated with eating more, moving less and having a higher risk of developing Type-2 diabetes.

However, “it was not clear whether glucose intolerance was due to the changes in food intake or energy expenditure or to the sleep deprivation itself,” explained a team of researchers from Toho University in Japan.

In the study done over mice, blood glucose levels were found significantly higher in the sleep deprivation group than controls after one six-hour session of wakefulness.

Triglyceride (fat) levels and the production of glucose in the liver also increased in the sleep deprivation group after a single wake period.

Elevated liver triglycerides are associated with insulin resistance, or the inability of the body to process insulin properly.

Diabetes
Representational image. Pixabay

In addition, lack of sleep changed the expression of enzymes that regulate metabolism in the liver in the sleep deprivation group.

These findings suggest that “intervention studies designed to prevent sleep deprivation-induced hepatic steatosis and insulin resistance should be performed in the future,” the researchers noted.

For the study, published in the American Journal of Physiology — Endocrinology and Metabolism, the team examined two groups of mice.

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One group was kept awake for six hours each night (“sleep deprivation”), while the control group was allowed to sleep as desired.

The team offered unlimited high-fat food and sugar water — mimicking lifestyle-related food choices that people make — to both groups prior to the study.

During the sleep/wake period, the animals also had limited opportunity for physical activity. (IANS)

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Having a Cup of Coffee Can Help You Fight Obesity, Diabetes

“The results were positive and we now need to ascertain that caffeine as one of the ingredients in the coffee is acting as the stimulus or if there’s another component helping with the activation of brown fat. We are currently looking at caffeine supplements to test whether the effect is similar,” Symonds added

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A patron holds an iced beverage at a Starbucks coffee store in Pasadena, Calif., July 25, 2013. VOA

Drinking a cup of coffee can be helpful in fighting obesity and diabetes as it stimulates body’s fat-fighting defences, says a new study.

The study, published in Scientific Reports journal, found components which could have a direct effect on “brown fat” functions, an important part of the human body which plays a key role in how quickly we can burn calories as energy.A

Brown adipose tissue (BAT), also known as brown fat, is one of two types of fat found in humans and other mammals. Its main function is to generate body heat by burning calories (opposed to white fat, which is a result of storing excess calories).

People with a lower body mass index (BMI) therefore have a higher amount of brown fat.

“Brown fat works in a different way to other fat in your body and produces heat by burning sugar and fat, often in response to cold. Increasing its activity improves blood sugar control as well as improving blood lipid levels and the extra calories burnt help with weight loss,” said study’s co-director Michael Symonds, Professor at the University of Nottingham.. A

“This is the first study in humans to show that something like a cup of coffee can have a direct effect on our brown fat functions. The potential implications of our results are pretty big, as obesity is a major health concern for society and we also have a growing diabetes epidemic and brown fat could potentially be part of the solution in tackling them,” he noted.

A barista pours steamed milk into a cup of coffee at a cafe in Los Angeles, Sept. 22, 2017. State health officials proposed a regulation change Friday that would declare coffee doesn't present a significant cancer risk, countering a California court ruling.
A barista pours steamed milk into a cup of coffee at a cafe in Los Angeles, Sept. 22, 2017. VOA

For the study, the researcehes started with a series of stem cell studies to see if caffeine would stimulate brown fat. After finding the right dose, they then moved on to humans to see if the results were similar.

They used a thermal imaging technique to trace the body’s brown fat reserves. The non-invasive technique helps the team to locate brown fat and assess its capacity to produce heat.

“From our previous work, we knew that brown fat is mainly located in the neck region, so we were able to image someone straight after they had a drink to see if the brown fat got hotter,” he said.

Also Read: Poor Sleep Quality Associated with Reduced Memory in Senior Citizens

“The results were positive and we now need to ascertain that caffeine as one of the ingredients in the coffee is acting as the stimulus or if there’s another component helping with the activation of brown fat. We are currently looking at caffeine supplements to test whether the effect is similar,” Symonds added.

“Once we have confirmed which component is responsible for this, it could potentially be used as part of a weight management regime or as part of glucose regulation programme to help prevent diabetes,” he concluded. (IANS)