Get subscribed to our newsletter
Get interesting updates to your email inbox.
Have you ever wondered what is the importance of day and night, what is the role of sleep, how do we set a good circadian rhythm? Well all this revolves around the hormone melatonin!
Setting up the circadian rhythm helps in production of good amounts of melatonin hormone. Melatonin does help in reducing the pigmentation, anti-ageing and also reduces hair fall so on and so forth.
Dr. Pallavi Sule, Dermatologist and Aesthetic Physician, starts by first explaining the meaning of Melatonin: “Melatonin is a hormone primarily secreted by the pineal gland which is known to regulate the sleep-wake cycle. Usually it is consumed in the form of tablets to help people in jet lag, shift works by regulating the circadian cycle as a short term treatment for trouble in sleeping”.
Please follow NewsGram on Instagram to get updates on the latest news
How does melatonin get secreted?
The pineal gland is sensitive to light. When it is dark the body secretes more melatonin and prepares the body to sleep and when it is day/ light (artificial lights) the production of the hormone decreases. Low levels of the hormone give brain signals to stay awake.
So what’s new about this hormone and why is it studied in more detail than before?
Sule said: “The hormone is also known for its antioxidant benefits!! We all are living in a very stressful environment, be it the external or internal stressors like pollution, food consumed (adulteration), solar radiation, sleep patterns, work environments and so forth!! Any kind of stress releases free oxygen radicals in the body, which damages our DNA, causing degenerative diseases and autoimmune diseases. Oxidative damage also leads to aging and hair fall which we know is one of the major causes.The hormone serves as a potent antioxidant, presumptive anti aging substance and anti cancer agent.”
Let’s understand how sleeping according to the body clock helps our body in general health and well being!
Sule further elaborates on this imperative subject adding, “Maintaining good sleep hygiene and a good sleep quality has many advantages. The sleep wake cycle governs two hormones- Cortisol and Melatonin.”
Please follow NewsGram on Twitter to get updates on the latest news
Release of Human Growth Hormone: Experts estimate that 75 per cent of this hormone is released during sleep. It is released in the Stage 3 of sleep cycle which is usually 1-1.5 hrs after one falls asleep. Sleep deprivation or altered cycles affects the release of this hormone. In children it will affect the growth and health.
Sleep and its relation with Liver: There is a great relationship between sleep cycles and liver functions. Scientific studies suggest that most patients with advanced liver diseases have disturbed sleep patterns. The liver has its own clock for detoxification and regulation of hormones. Disturbed sleep results in raised cortisol levels (stress levels) and vice versa. This hampers the regulation of hormones by the liver. Here, now the liver is overworked and cortisol levels in the body are high during daytime. This circulating cortisol hampers the liver’s regulations of melatonin and so the melatonin hormone levels are also high during daytime. Resulting in day time fatigue and drowsiness, and night time alertness.
Lastly, how can we increase melatonin levels?
“Many formulations are available in the market in the form of tablets and gels for topical application. But we must not forget the most important factor in production of the right amount of melatonin hormone in the body is sleep.” (IANS)
The US researchers have discovered a class of immune cells that plays a role in miscarriage, which affects about a quarter of pregnancies.
Researchers at the University of California-San Francisco found that the recently discovered subset of cells known as extrathymic Aire-expressing cells in the immune system may prevent the mother's immune system from attacking the placenta and fetus.
The researchers showed that pregnant mice who did not have this subset of cells were twice as likely to miscarry, and in many of these pregnancies fetal growth was severely restricted.
ALSO READ: Can You Drink Coffee While You're Pregnant?
"When you're pregnant, the immune system is seeing the placenta for the first time in decades -- not since the mother made a placenta when she herself was a fetus," said Eva Gillis-Buck, from UCSF.
"Our research suggests that this subset of immune cells is carrying out a sort of 'secondary education' -- sometimes many years after the better-known population of the educator cells have carried out the primary education in the thymus -- teaching T cells not to attack the fetus, the placenta and other tissues involved in pregnancy," she added. The findings are published in the journal Science Immunology.
The immune system has to be educated not to attack one's own tissues and organs to prevent autoimmune disease. But pregnancy presents a unique challenge since the fetus expresses proteins found in the placenta as well as proteins whose genetics are distinct from the mother.
ALSO READ: The Importance of a Good Mattress for Pregnant
"It was a conceptual leap to link Aire-expressing cells, which are critical for preventing autoimmune disease, to pregnancy," said Tippi Mackenzie, Professor of Surgery at UCSF's Center for Maternal Foetal Precision Medicine.
In the thymus, Aire-expressing cells begin interacting with other immune cells very early in life to teach them what not to attack. The thymus begins to shrink and is nearly gone by adulthood, by which time most immune cells have been educated. But as the thymus shrinks, the population of eTACs in lymph nodes and the spleen expands, the researchers explained.
The study suggests a healthy pregnancy may depend on having these cells around, they added. (IANS/KB)
The tiny emojis being shared on billions of devices worldwide can play a major role in digital communication, with most people saying that emoji compels them to feel more empathy towards others, according to an Adobe report.
Adobe's global emoji study found that emoji even helps people overcome language barriers and form connections that would otherwise be difficult to do.
"We were surprised and delighted by the discoveries made in the survey, most notably how enthusiastic respondents were for emoji as a means to express themselves," the company said in a statement.
ALSO READ: Emoji- A Choice for Interracial Couple
Emojis sometimes get criticized for being overly saccharine, but this sweetness is key when it comes to diffusing some of the heaviness of online communication.
"Many of the emoji are focused on positive emotions, so it's easy to insert them into our conversations and lighten the mood," the Adobe study said.
It's not surprising that over half of those surveyed feel more comfortable using emojis than talking on the phone or in person.
ALSO READ: Apple Previews Selection of Emojis on World
This applies to less intense situations too. Dating, for example, can be tricky — especially when it's online or via digital apps, as it often is now.
The study also found that emoji even helps people overcome language barriers and form connections that would otherwise be difficult to do.
In celebration of World Emoji Day on Saturday, Adobe's '2021 Global Emoji Trend Report' surveyed 7,000 people in the US, the UK, Germany, France, Japan, Australia, and South Korea. (IANS/KB)
Following the grand Richard Branson show where he carried Andhra Pradesh-born Sirisha Bandla and fellow space travelers on his shoulders after successfully flying to the edge of space, it is time for Amazon Founder Jeff Bezos to applaud Sanjal Gavande, one of the key engineers who designed the New Shephard rocket set to take Bezos and the crew to space on July 20.
Billionaire Bezos is set to fly to the edge of space aboard what is touted as the world's first unpiloted suborbital flight. Born in Kalyan, Maharashtra, Gavande is a systems engineer at Blue Origin who always dreamt of designing aerospace rockets.
ALSO READ: Jeff Bezos Used To Review Products On Amazon
After completing Bachelor's in mechanical engineering from the University of Mumbai, she flew to the US in 2011 to pursue a Master's in mechanical engineering from the Michigan Technological University. She also applied for an engineering job at the US space agency NASA but finally landed her dream job at Blue Origin
Sirisha flew to the US in 2011 to pursue a Master's in mechanical engineering from the Michigan Technological University.IANS
Bezos, his brother Mark, aviation pioneer Mary Wallace 'Wally' Funk, and other passengers are set to liftoff from west Texas and travel just beyond the edge of space on July 20. Blue Origin announced this week that Oliver Daemen, an 18-year-old high school graduate from the Netherlands, would join the crew.
Oliver is the son of millionaire Joe Daemen, Founder, and CEO of the Dutch investment company Somerset Capital Partners. Blue Origin, however, did not reveal how much Daemen paid for his son's trip to space. Bezos chose July 20 as the launch date to honor the 52nd anniversary of the Apollo 11 moon landing.
ALSO READ: “We are Tiny”: Elon Musk to NASA
The launch site for Blue Origin's first human flight will be in a remote location north of Van Horn, Texas, from where the firm had launched New Shepard for previous flights. Blue Origin has received final approval from the Federal Aviation Administration (FAA) to carry humans on the New Shepard rocket into space.
On July 12, Bandla touched the edge of space with three others, including Virgin Galactic's billionaire CEO Richard Branson. Bandla vaulted into space onboard VSS Unity 22. After the successful spaceflight, Branson carried the Indian-American on his shoulders while celebrating their flight to space, at Spaceport America in New Mexico. (IANS/KB)