Tuesday May 22, 2018

Small Head Blows Can Also Increase Risk of Dementia

In total, 357,558 participants, whose average age was 49, were tracked.

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Concussion without loss of consciousness led to 2.36 times the risk for dementia, showed the findings published in the journal JAMA Neurology.
Head blows can cause dementia, Pixabay
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Even head blows that do not result in loss of consciousness may cause brain changes that increase the risk of dementia, new research has found.

The study, which tracked more than 350,000 participants, showed that the likelihood of dementia more than doubled following concussion.

Concussion without loss of consciousness led to 2.36 times the risk for dementia, showed the findings published in the journal JAMA Neurology.

These risks were slightly elevated for those in the loss-of-consciousness bracket (2.51) and were nearly four times higher (3.77) for those with the more serious moderate-to-severe traumatic brain injury.

The researchers identified participants from two databases. The first group included all-era veterans whose traumatic brain injuries could have occurred during civilian or military life.

The second group included veterans serving in Iraq and Afghanistan, for whom most of these injuries had occurred in combat zones, such as from shockwaves in blasts.

Even head blows that do not result in loss of consciousness may cause brain changes that increase the risk of dementia, new research has found.
Dementia, Pixabay

“The findings in both groups were similar, indicating that concussions occurring in combat areas were as likely to be linked to dementia as those concussions affecting the general population,” said first author Deborah Barnes, Professor at the University of California, San Francisco, US.

In total, 357,558 participants, whose average age was 49, were tracked.

Half had been diagnosed with traumatic brain injury, of which 54 per cent reported experiencing concussion.

The study followed the participants for an average of 4.2 years.

“There are several mechanisms that may explain the association between traumatic brain injury and dementia,” said senior author and principal investigator Kristine Yaffe, Professor at the University of California, San Francisco.

Also Read: Researchers Identified Protein Associated With Breast Cancer

 “There’s something about trauma that may hasten the development of neurodegenerative conditions. One theory is that brain injury induces or accelerates the accumulation of abnormal proteins that lead to neuronal death associated with conditions like Alzheimer’s disease,” Yaffe said.

Alzheimer’s disease is the most common form of dementia.

“It’s also possible that trauma leaves the brain more vulnerable to other injuries or ageing processes,” Yaffe said. (IANS)

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New Study Shows That Elderly With Symptoms of Depression Are More Prone to Memory Problems

"Since symptoms of depression can be treated, it may be possible that treatment may also reduce thinking and memory problems," said study author Adina Zeki Al Hazzouri of the University of Miami Miller School of Medicine in Florida, US.

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The researchers found that greater symptoms of depression were linked to worse episodic memory -- a person's ability to remember specific experiences and events.
representational image. pixabay

Depression may speed up brain ageing and lead to memory problems in older adults, suggests new research that offers hope of finding a new way to treat memory issues.

“Since symptoms of depression can be treated, it may be possible that treatment may also reduce thinking and memory problems,” said study author Adina Zeki Al Hazzouri of the University of Miami Miller School of Medicine in Florida, US.

The study, published in the journal Neurology, also showed that older people with greater symptoms of depression may have structural differences in the brain compared to people without symptoms.

“With as many as 25 per cent of older adults experiencing symptoms of depression, it’s important to better understand the relationship between depression and memory problems,” Zeki Al Hazzouri said.

The study involved over 1,000 people with an average age of 71.

The researchers found that greater symptoms of depression were linked to worse episodic memory -- a person's ability to remember specific experiences and events.
representational image, pixabay

At the beginning of the study, all the participants had brain scans, a psychological exam and assessments for memory and thinking skills. Their memory and thinking skills were tested again an average of five years later.

At the start of the study, 22 per cent of the participants had greater symptoms of depression.

The researchers found that greater symptoms of depression were linked to worse episodic memory — a person’s ability to remember specific experiences and events.

Those with greater symptoms of depression had differences in the brain including smaller brain volume as well as a 55 per cent greater chance of small vascular lesions in the brain, the findings showed.

Also Read: Trauma in Childhood is Linked to Negative Outcomes in Adulthood 

“Small vascular lesions in the brain are markers of small vessel disease, a condition in which the walls in the small blood vessels are damaged,” said Zeki Al Hazzouri.

“Our research suggests that depression and brain ageing may occur simultaneously, and greater symptoms of depression may affect brain health through small vessel disease,” Zeki Al Hazzouri added. (IANS)