Saturday February 16, 2019

Research Shows Smoking Affects Leg Muscles

According to the researchers, smoking could directly damage the muscles by reducing the number of blood vessels in leg muscles,

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It is vitally important that we show people that the use of tobacco cigarettes has harmful consequences throughout the body, including large muscle groups needed for daily living, and develop strategies to stop the damage triggered by the detrimental components of cigarette smoke

If you believe that smoking affects only the lungs, then you may be wrong as a new study showed that components in cigarette smoke may directly damage the muscles in your leg as well.

According to the researchers, smoking could directly damage the muscles by reducing the number of blood vessels in leg muscles, which in turn reduce the amount of oxygen and nutrients the muscles received.

“It is vitally important that we show people that the use of tobacco cigarettes has harmful consequences throughout the body, including large muscle groups needed for daily living, and develop strategies to stop the damage triggered by the detrimental components of cigarette smoke,” said lead author Ellen Breen from the University of California-San Diego, US.

It is vitally important that we show people that the use of tobacco cigarettes has harmful consequences throughout the body, including large muscle groups needed for daily living, and develop strategies to stop the damage triggered by the detrimental components of cigarette smoke

Under a mouse model, a team of researchers from California along with Universidade Federal do Rio de Janeiro in Brazil and Kochi University in Japan, exposed the mice to smoke from tobacco cigarettes for eight weeks, either by inhalation or by injecting them with a solution bubbled with smoke.

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smoking could directly damage the muscles by reducing the number of blood vessels in leg muscles, which in turn reduce the amount of oxygen and nutrients the muscles received. Pixabay

The results, published in The Journal of Physiology, also showed that the reduced level of oxygen and nutrients due to reduced blood vessels may impact the metabolism and activity levels.

Read More: Avoid Foods Full of Trans Fats if You Are Worried About High Cholesterol Levels

Both these are risk factors for many chronic diseases including chronic obstructive pulmonary disease (COPD) and diabetes.
The study, however, could not identify the chemical responsible out of the 4,000 chemicals in a cigarette smoke that caused the muscle damage.

Researchers said that further study is needed to identify them, along with understanding the process by which they reduce the number of blood vessels. (IANS)

Next Story

New Device Equally Harmful as E-cigarettes

"If the current trend continues, tobacco use will cause more than eight million deaths annually by 2030 around the world," noted Sharma

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Talia Eisenberg, co-founder of the Henley Vaporium, uses her vaping device in New York, Feb. 20, 2014. VOA

While we know about the harmful effects of traditional cigarettes and vaping, new heated tobacco devices are no less toxic to the human lung cells than ordinary cigarette smoke, said researchers, including one of Indian-origin.

The study has compared new heated tobacco devices, which heat solid tobacco instead of an e-liquid, with vaping and traditional cigarettes showing that all the three are toxic to the cells.

In addition, these newer electronic nicotine delivery devices can destroy lung tissue leading to fatal diseases such as chronic obstructive pulmonary disease, lung cancer and pneumonia, and can increase the risk of developing asthma.

“Smoking is the leading cause of preventable death, and with the introduction of e-cigarettes in the last decade, the trend of nicotine uptake is not going to slow down in the near future,” said Pawan Sharma, a researcher at the University of Technology Sydney.

“The latest addition in this emerging trend is the planned and vigorous introduction of heated tobacco devices. They are commonly called next generation or heat-not-burn products. We know very little about the health effects of these new devices, so we designed this research to compare them with cigarette smoking and vaping,” added Sharma.

For the study, researchers tested the effects of all three nicotine sources on two types of cells taken from the human airways: epithelial cells and smooth muscle cells.

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A woman smokes an electronic cigarette in London, Aug. 19, 2015. VOA

In healthy lungs, epithelial cells act as the first line of defence to any foreign particles entering the airway while smooth muscle cells maintain the structure of the airway. However, smoking can lead to difficulty in breathing primarily by hampering the normal functions of these cells.

The team exposed the cells to different concentrations of cigarette smoke, e-cigarette vapour and vapour from a heated tobacco device, and measured whether this was damaging to cells and whether it affected the cells’ normal functions.

The findings, published in ERJ Open Research, showed that cigarette smoke and heated tobacco vapour were highly toxic to the cells both at lower and higher concentrations while e-cigarette vapour demonstrated toxicity mainly at higher concentrations.

Also Read- Here Comes The Novel Method to Predict Fatal Heart Disease

Importantly, the review of the European Respiratory Society’s Tobacco Control Committee’s own data on these devices has shown that, in rats, there is evidence of lung inflammation, and there is no evidence of improvement in lung inflammation and function in smokers who switch to heated tobacco, said Professor Charlotta Pisinger from the varsity.

“If the current trend continues, tobacco use will cause more than eight million deaths annually by 2030 around the world,” noted Sharma. (IANS)