Tuesday June 25, 2019

Soy-rich Food Decrease Risk of Bone Fractures in Breast Cancer Survivors

Breast cancer is the second most common cancer among women in the US, with one in eight women diagnosed with it during their lifetime

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Eating soy-rich food can decrease the risk of bone fractures in pre-menopausal breast cancer survivors, suggests a new study. The higher soy intake was linked to 77 per cent reduced risk of osteoporotic fractures in younger women, the study showed.

In the study, published in JNCI Cancer Spectrum journal, researchers at Yale University investigated the impact of exercise and soy food consumption on bone fracture rates among breast cancer survivors.

“The menopausal transition is known to be a period of high risk for bone loss, and given the relative scarcity of data related to fracture risk among younger women with breast cancer, this study marks an important contribution to this body of literature,” said the paper’s lead author, Evelyn Hsieh, Assistant Professor at Yale University.

“Our findings, in particular regarding the protective effects of soy food consumption, provide novel insight into how future interventions can be best tailored to different risk groups,” Hsieh said.

For the study, the team used data from the Shanghai Breast Cancer Survival study of 5,042 newly diagnosed breast cancer survivors in the age group of 20-75.

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Bone fracture (Representational image). Pixabay

The study found soy-based foods that are rich in isoflavones provide a natural selective estrogen receptor modulator (SERM), which helps in increasing the bone mineral density.

Previous studies have showed the use of tamoxifen, a SERM or drug, that is prescribed for breast cancer patients, reduces risk of fractures.

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Several treatments for breast cancer can cause premature menopause and decrease bone mineral density, leading to a higher incidence of osteoporosis-related fractures among survivors compared with healthy women in the same age group.

Breast cancer is the second most common cancer among women in the US, with one in eight women diagnosed with it during their lifetime. (IANS)

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Why Do Women Face Higher Heart Disease Risk after Breast Cancer? Find Out Here!

The cardiovascular effects may occur more than five years after radiation exposure

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Women, Heart Disease, Breast Cancer
Heart disease appears more commonly in women treated for breast cancer because of the toxicities of chemotherapy. Pixabay

Researchers have found that postmenopausal women with breast cancer are at greater risk of developing cardiovascular disease.

“Heart disease appears more commonly in women treated for breast cancer because of the toxicities of chemotherapy, radiation therapy and use of aromatase inhibitors, which lower estrogen,” said JoAnn Pinkerton, Professor at the University of Virginia.

The cardiovascular effects may occur more than five years after radiation exposure, with the risk persisting for up to 30 years.

“Heart-healthy lifestyle modifications will decrease both the risk of recurrent breast cancer and the risk of developing heart disease,” Pinkerton said.

Women, Heart Disease, Breast Cancer
Researchers have found that postmenopausal women with breast cancer are at greater risk of developing cardiovascular disease. Pixabay

The goal of the study was to compare and evaluate risk factors for cardiovascular disease in postmenopausal women who are survivors of breast cancer and women without breast cancer.

For the findings, more than 90 postmenopausal breast cancer survivors were compared with 192 postmenopausal women.

The researchers found that postmenopausal women who are survivors of breast cancer showed a markedly stronger association with metabolic syndrome, diabetes, atherosclerosis, hypertriglyceridemia and abdominal obesity, which are major risk factors for cardiovascular disease.

The risk of cardiovascular mortality similarly increased to match death rates from cancer itself.

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“Women should schedule a cardiology consultation when breast cancer is diagnosed and continue with ongoing follow-up after cancer treatments are completed,” she added.

The study was published in the Menopause: The Journal of the North American Menopause Society. (IANS)