Friday February 28, 2020

Consumption of Soybean Oil May Affect Neurological Conditions: Study

Soybean oil diet may trigger genetic changes in brain

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Soybean oil
Soybean oil not only leads to obesity and diabetes but may also affect neurological conditions. Wikimedia Commons

Widely consumed soybean oil not only leads to obesity and diabetes but may also affect neurological conditions like autism, Alzheimer’s disease, anxiety and depression, report researchers from University of California Riverside, including one of Indian origin.

In a study conducted on mice, the scientists found pronounced effects of the soybean oil on the hypothalamus where a number of critical processes take place.

The research team discovered nearly 100 genes – including the ‘love hormone’ oxytocin produced in hypothalamus — affected by the soybean oil diet.

Soybean oil  brain
In a study conducted on mice, the scientists found pronounced effects of the soybean oil on the hypothalamus where a number of critical processes take place. Pixabay

“The hypothalamus regulates body weight via your metabolism, maintains body temperature, is critical for reproduction and physical growth as well as your response to stress,” said Margarita Curras-Collazo, an associate professor of neuroscience and lead author on the study published in the journal Endocrinology.

The research team has not yet isolated which chemicals in the oil are responsible for the changes they found in the hypothalamus.

“But they have ruled out two candidates. It is not linoleic acid, since the modified oil also produced genetic disruptions; nor is it stigmasterol, a cholesterol-like chemical found naturally in soybean oil,” the study noted.

Identifying the compounds responsible for the negative effects is an important area for the team’s future research.

“This could help design healthier dietary oils in the future,” said Poonamjot Deol, first author on the study.

“If there’s one message I want people to take away, it’s this: reduce consumption of soybean oil,” Deol added.

Soybean oil brain
Consumption of Soybean oil may lead to autism. Pixabay

The team compared mice fed three different diets high in fat: soybean oil, soybean oil modified to be low in linoleic acid, and coconut oil.

They believe this discovery could have ramifications not just for energy metabolism,but also for proper brain function and diseases such as autism or Parkinson’s disease.

“However, it is important to note there is no proof the oil causes these diseases,” the authors wrote.

Te same research team found in 2015 that soybean oil induces obesity, diabetes, insulin resistance, and fatty liver in mice. Then in a 2017 study, the same group learned that if soybean oil is engineered to be low in linoleic acid, it induces less obesity and insulin resistance.

The team said the findings only apply to soybean oil — not to other soy products or to other vegetable oils.

“Do not throw out your tofu, soymilk, edamame, or soy sauce,” said Frances Sladek, a UCR toxicologist and professor of cell biology.

“Many soy products only contain small amounts of the oil, and large amounts of healthful compounds such as essential fatty acids and proteins”.

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This study utilized male mice. Because oxytocin is so important for maternal health and promotes mother-child bonding, similar studies need to be performed using female mice.

Coconut oil, which contains saturated fats, produced very few changes in the hypothalamic genes, said the researchers. (IANS)

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Here’s Why Less Consumption of Fruits and Vegetables Can Cause Anxiety

One in nine women had an anxiety disorder compared to one in fifteen men, the study said

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Vegetables
The study, published in the International Journal of Environmental Research and Public Health, found that those who consumed less than three sources of fruits and vegetables daily, there was at least at 24 per cent higher odds of anxiety disorder diagnosis. Pixabay

People who have low fruit and vegetable intakes have a higher likelihood of being diagnosed with an anxiety disorder, say researchers.

The study, published in the International Journal of Environmental Research and Public Health, found that those who consumed less than three sources of fruits and vegetables daily, there was at least at 24 per cent higher odds of anxiety disorder diagnosis.

“This may also partly explain the findings associated with body composition measures. As levels of total body fat increased beyond 36 per cent, the likelihood of anxiety disorder was increased by more than 70 per cent,” said co-author Jose Mora-Almanza, a Mitacs Globalink Intern who worked with the study at Kwantlen Polytechnic University in Canada.

According to the researchers, increased body fat may be linked to greater inflammation. Emerging research suggests that some anxiety disorders can be linked to inflammation.

“Our findings are in keeping with previous research which has also indicated that women are more vulnerable to anxiety disorders than men,” said study co-author Karen Kobayashi.

The study team analysed data from the Canadian Longitudinal Study on Aging which included 26,991 men and women between the ages of 45 and 85. Other factors associated with anxiety disorders among mid-age and older Canadians

In addition to diet and body composition measures, the prevalence of anxiety disorders also differed by gender, marital status, income, immigrant status and several health issues.

One in nine women had an anxiety disorder compared to one in fifteen men, the study said.

Vegetables
People who have low fruit and vegetable intakes have a higher likelihood of being diagnosed with an anxiety disorder, say researchers. Pixabay

The prevalence of anxiety disorders among those who had always been single (13.9 per cent) was much higher than among those who were living with a partner (7.8 per cent).

Approximately one in five respondents with household incomes under $20,000 per year had anxiety disorders, more than double the prevalence of their richer peers.

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“We were not surprised to find that those in poverty had such a high prevalence of anxiety disorders; struggling to afford basics such as food and housing causes relentless stress and is inherently anxiety inducing,” said study co-author Hongmei Tong, Assistant Professor at MacEwan University in Canada. (IANS)