Tuesday May 22, 2018

Reduce the Spread of Cancer With this Protein, According to Research by University of Guelph, Ontario

Researchers have discovered a new protein that could reduce the spread of cancer by binding the cancer cells together and allowing them to invade tissues

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Cancer rate declined generally but increased in this particular age group. IANS.
Cancer rate declined generally but increased in this particular age group. IANS.
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New York, Nov 19: Researchers have discovered a new protein that could reduce the spread of cancer by binding the cancer cells together and allowing them to invade tissues.

The study conducted by the researchers from University of Guelph, Ontario, has identified a protein called cadherin-22, a potential factor in cancer metastasis or the spread of cancer.

The protien also decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 per cent.

“Cadherin-22 could be a powerful prognostic marker for advanced cancer stages and patient outcomes,” said lead author Jim Uniacke, a professor at the varsity.

“If you can find a treatment or a drug that can block cadherin-22, you could potentially prevent cancer cells from moving, invading and metastasizing.”

The study, published in the journal Oncogene, looks specifically at hypoxia, a condition in which the tissues receive less oxygen.

The researchers found that it is precisely under conditions of low oxygen that cancer cells trigger the production of cadherin-22, putting in motion a kind of protein boost that helps bind cells together, enhancing cellular movement, invasion and likely metastasis.

Studying breast and brain cancer cells in a hypoxia incubator, the researchers discovered that cadherin-22 is involved in this process to enable the spread of cancer cells.

For both cancer types, the research team used molecular tools to reduce the amount of cadherin-22.

They placed the human cancer cells into the incubator and lowered the oxygen to a level comparable to that in a tumour. The cells failed to spread.

“One very powerful and common tool in cell and molecular biology labs is, you can remove a protein from a cell and see how that cell behaves without it.

“We culture our cancer cells in this very low-oxygen environment, and they start behaving like they are inside a low-oxygen tumour,” Uniacke added. (IANS)

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Lifestyle Habits That Affect Breast Cancer Risk

Changing lifestyle habits, increasing work pressure and stress levels have left modern-day individuals with no time to pay heed to their health and one disease that seems to be emerging because of irregular lifestyle is breast cancer. So make sure you are keeping a check on habits that can lead to this disease.

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Pink Ribbon Campaign
Breast Cancer. Pixabay

Changing lifestyle habits, increasing work pressure and stress levels have left modern-day individuals with no time to pay heed to their health and one disease that seems to be emerging because of irregular lifestyle is breast cancer. So make sure you are keeping a check on habits that can lead to this disease.

Meher Patel, Director at DIVA, Centre for Breast Care (partner with cosmetic brand AVON’s #PayAttention campaign that raises awareness of breast cancer), says:

* Lack of physical activity:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
Yoga is also a good physical exercise. Wikimedia

Don’t be proud of being laid back. One of the main reasons is that excess weight causes the body to produce and circulate more estrogen and insulin, hormones that can stimulate cancer growth. It is crucial to keep your body fit at every stage of life continuously using all body parts to sweat out intoxicants that one consumes in this polluted, fast-paced world.

* Alcohol and smoking:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
Bottles of Alcohol, Wikimedia

The downside of relaxing in this modern world. The more glasses of drinks you down on the weekend, or packets of cigarettes you puff up, the more you are at risk of breast cancer. Also, for the night owls, it is advisable to find the right balance since irregular patterns of work, long hours and late nights are more likely found to be struck by cancer in the later years of life.

* Long night-shifts at work:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
representational image. Pixabay

After conducting a survey with 300 women-some of whom worked at night, some of whom didn’t the survey found that those who had worked nights for 30 or more years were twice as likely to have developed the disease.

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.

* Hormone replacement therapy (HRT) and contraceptive pills:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
Pills, representational Image. Pixabay

Medical improvisations you don’t need! Avoid using the viral popular HRT or contraception tablets to abnormally treat menopausal symptoms and unwanted pregnancy.

* Overweight:

Renuka Prasad- Joint Secy (Hon.) at Indian Cancer Society too has problems to share that can lead to this disease.
representational image. pixabay

Start eating healthy and avoid eating out. Putting on weight in adulthood (after the age of 18) with those extra munchies and burgers, or being overweight after menopause can also lead to breast cancer.

Also Read:Effective Treatment to Protect Cancer Patients From Blood Clots

* Other causes:

A few other causes that women tend to overlook is the excess use of deodorants and perfumes, underwired bras, bumping or bruising of breasts, breast implants and abortions that can also be potential threats to breast cancer. (IANS)