Friday, December 4, 2020
Home Life Style Health & Fitness Synthetic Mini-Antibody Found in Blocking Coronavirus

Synthetic Mini-Antibody Found in Blocking Coronavirus

The new synthetic mini-antibody blocks the receptor-binding domains

In a significant development, scientists have identified a synthetic mini-antibody that turned out to be particularly effective in blocking the new coronavirus from entering human cells.

The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2.

Follow NewsGram on Twitter to stay updated about the World news.

To enable the virus to hook onto the cell surface, the spike protein binds ACE2 using three finger-like protrusions, called the receptor-binding domains (RBDs).

The new synthetic mini-antibody blocks the RBDs, therefore, has the potential to stop the virus from entering human cells said the researchers from EMBL Hamburg, CSSB, Karolinska Institutet, and the University of Zurich.

Follow NewsGram on Instagram to keep yourself updated.

EMBL Hamburg searched through the existing libraries to find sybodies that could block SARS-CoV-2 from infecting human cells.

Among the best binders, one called “sybody 23” turned out to be particularly effective in blocking the RBDs.

Synthetic mini-antibody
In future work, the scientists will perform further analyses to confirm whether sybody 23 could be an effective COVID-19 treatment. Unsplash

“Getting the results so quickly was only possible because the methodologies we used had already been established for other research projects unrelated to SARS-CoV-2. Developing these tools would have taken significantly more time and resources,” said Christian Low from EMBL Hamburg.

Nanobodies, small antibodies found in camels and llamas, are promising as tools against viruses due to their high stability and small size.

Follow NewsGram on LinkedIn to know what’s happening around the world.

Although obtaining them from animals is time-consuming, technological advances now allow for rapid selection of synthetic nanobodies, called sybodies.

A technology platform to select sybodies from large synthetic libraries was recently developed in the lab of Markus Seeger at the University of Zurich, and made available for this study.

Also Read: Delhi Government Removes Schemes On Approval To Standalone Restaurants

The results hold out the promise of a potential way to treat COVID-19, the team said.

In future work, the scientists will perform further analyses to confirm whether sybody 23 could be an effective COVID-19 treatment. (IANS)

STAY CONNECTED

19,120FansLike
362FollowersFollow
1,778FollowersFollow

Most Popular

Affordable Treatment For Poor Children With HIV

GENEVA - Affordable treatment will soon be available for children living with HIV in low- and middle-income countries thanks to an agreement between the...

Glucosamine Supplements Might Reduce Mortality Rate

Researchers have revealed that glucosamine supplements may reduce overall mortality almost as well as regular exercise does. Glucosamine sulfate might provide some pain relief for...

AI Interprets Retinal Images To Identify Alzheimer’s Disease

A form of artificial intelligence (AI) designed to interpret a combination of retinal images was able to successfully identify a group of patients who...

Development of Facial Recognition To Identify Masked Faces

Facial recognition technology created after the onset of the Covid-19 pandemic shows that some software developers have made demonstrable progress at recognizing masked faces,...

Cancer Survivors Prone To Higher Death Risk By Flu

Survivors from a wide range of cancers are more likely than people in the general population to be hospitalized or die from seasonal influenza-even...

2020 Records As One of The Three Warmest Years

Climate change continued its relentless march in 2020, which is on track to be one of the three warmest years on record. 2011-2020 will be...

What Does the Music Industry Look Like In 2021?

Whether it’s shuffling through songs on their iTunes playlist, discovering new beats on Spotify, or tuning into Instagram Live to see their favorite musicians...

Companies Need More Strength in Cyber Security

As the Covid pandemic has brought about a sea change in the operations of most companies with work from home becoming the trend over...

Recent Comments