Get subscribed to our newsletter
Get interesting updates to your email inbox.
Combining three assays together, researchers have developed a new way to spot melanoma skin cancer cells circulating in the blood that could provide a new avenue for cancer diagnosis and therapies.
With the new approach, the researchers raised detection rates to 72 per cent which is higher than using one test, said the study published in the British Journal of Cancer.
The research has the potential to significantly improve the monitoring of cancer patients and guide future treatment.
“These preliminary findings are a first step towards a new way to stop melanoma from spreading around the body,” said lead researcher Elin Gray, Associate Professor at Edith Cowan University in Australia.
“Cancer spreads around the body when circulating tumour cells (CTCs) shed from the primary tumour and travel through the blood to form secondary tumours (metastases) in other organs.
“If we can find a way to reliably detect these cells, then we have a chance to stop melanoma in its tracks with a powerful diagnostic tool and perhaps opportunities for therapies in the future,” Gray said.
Until now melanoma circulating tumour cells have proved to be incredibly elusive, with detection rates wildly varying from 40 to 87 per cent.
“We now understand that CTC detection cannot be resolved with a one-size-fits-all approach,” she said.
“There is a huge amount of variety in the shape and bioactivity of these CTCs and so they all look different and respond differently to assay tests,” Gray said.
The researcher explained that melanoma CTCs are hidden among thousands of other cells and matter in the blood.
Armed with a better understanding of the complexity of the task, the researchers tried a multifaceted approach to detecting melanoma CTCs.
Also Read- Hair and Skin Care Tips for Bikers
“By combining three assays together, we raised detection rates to 72 per cent, which was a significantly and consistently higher result than using one test,” Gray said.
“We are confident this approach is a move towards the reliable detection of CTCs, but we now need to tweak the assay to include a better combination to capture the broadest range of CTCs,” she added. (IANS)
As the nation celebrated the 114th birth anniversary of his father - renowned poet Harivansh Rai Bachchan - megastar Amitabh Bachchan remembered his dad as he penned a heartfelt note for him. The actor took to his blog where he poured his heart out and also shared an unseen photo with his father. The image in question is from Big B's wedding in 1973, where the two are caught in a sweet moment as they look at each other.
Amitabh Bachchan wrote on his blog,
"My Father , my all .. November 27th his birth in the year 1907 .. Which makes it his 114th Anniversary .. He is in the heavens, with my Mother and they celebrate .. as do we , in thought word and deed .. (sic). But first."
He then posted the picture followed by elaborate paragraphs. The megastar wrote,
"Those rare moments when one would find himself rushing against the winds to prevent the distance between us and to close it down as soon as it can be. The day of my wedding and his expression of fulfilment to not just be in congratulation but instead to be in the face of a belief, a chime, an ultimate season of love and great passion, of the quarries of the fears and conditionings of these deprived gym routines kart ..(sic)". "This could have been unknown for long facilitating years, to give not expected versions and lastly large scale informations of the insides ; but as time passed by, as does now , they explained purposely, the values of education and similarity .. Be in peace and love .. (sic)",
the veteran actor concluded his note. (IANS/ MBI)
Keywords: Amitabh Bachchan, Harivansh Rai Bachchan, actor, blog, birth anniversary, 114th birthday
By Plabita Sharma
The World Vegan month of November usually brings with itself an increased amount of dialogue and searches about Vegan lifestyle, sustainable living and clean beauty. Before pondering any further, it is important to understand what the Vegan lifestyle is and how it goes beyond the concept of consuming a plant-based diet. Veganism essentially is a lifestyle that is driven by compassionate choices and an increased awareness of one's actions on the world. Thus motivated by the two, a vegan individual usually carefully curates their day-to-day practices in a manner that does little to no- harm to the planet, the people and all of its inhabitants.
Beauty as industry has time and again been scrutinised for its effects on the consumers and the ecosystem - this can be during the manufacturing process or the effect it has on the consumer's thought processes. Now, as the world moves towards adopting Global Sustainability Goals, committing to a world that works with the natural resources instead of against them - it is only fair for each individual to be curious about making the right choices to make their beauty bag as consciously curated as possible. With multiple brands coming up with new standards of vegan and sustainable beauty, many consumers are left confused and doubting the authenticity of these claims. So here is a quick guide that can help you make the right choices:
Vegan and cruelty free labels: Keeping true to the traditional meaning of Vegan - any vegan beauty product means that it is completely plant based and has no animal ingredients or any of their by-products like honey, beeswax, dairy product etc. Similarly, cruelty-free as a label means that the ingredients or the final product did not test on animals or harm any animals during the production process. One way to test the authenticity is to check if these products are legally certified by PETA (People for the Ethical Treatment of Animals), or verified by Vegan organisations as The Vegan Society and others. Cruelty-free and vegan products are also generally categorized by having cleaner and gentler formulas as they are mostly deprived of harsh chemicals and solvents.
Any vegan beauty product means that it is completely plant based and has no animal ingredients or any of their by-products like honey, beeswax, dairy product etc. | Photo by Drew Dizzy Graham on Unsplash
Ethical and natural ingredients: It is equally important to invest in products that use ethically sourced and sustainably harvested ingredients. Since most vegan products tend to be plant derived it is of utmost value to ensure that while the source is nature, the impact of manufacturing is also minimal so that there is no harm done to the environment. Often the face scrubs used by us are most damaging not just to the face and to the marine life as well; thus opting for more natural ingredients rather than synthetic ones is quite beneficial. Some natural scrubbing ingredients are sugar, salt, coffee which are safe for the coral reefs and far gentler than synthetic scrubs.
It is equally important to invest in products that use ethically sourced and sustainably harvested ingredients. | Photo by Brooke Lark on Unsplash
Sustainable and ecofriendly packaging: While the ingredients and formulation can be certified, it is also important to pay attention the quality, material and nature of the packaging in which the product is being stored. With an increase in clean-beauty standards, the consumption of such products has also increased, thus giving brands the opportunity to further develop their packaging in a manner that is sustainable and its increased quantity does not harm the environment. This could translate into using raw materials that are recycled and can be renewed or even introducing the concept of up-cycling the product packaging for decoration or storage purposes. Fore example, The Body Shop has recently launched a new line of vegan hair care and body butters; that are not only made of 95 per cent ingredients of natural origin but the packaging is made of recycled plastic that can further be recycled thus continuing the recycling system. Their makeup brushes also have wooden handles instead of plastic ones this adds to their classy appearance and use of ecofriendly material.
The Body Shop has recently launched a new line of vegan hair care and body butters; that are not only made of 95 per cent ingredients of natural origin but the packaging is made of recycled plastic. | Photo by Oli Dale on Unsplash
The above is a small snippet in a long list of things that can help contribute to a cleaner and more consciously lifestyle. Where demand increase, supply follows - as people begin to demand ethical, responsible production and products, more and more brands have begun to deliver. Household names such as The Body Shop have pioneered conversations on clean, green and sustainable beauty for decades - thus making them a frontrunner for several old time vegan people.
(Article originally published on IANSlife) (IANS/ MBI)
Keywords: Beauty, makeup, clean, November, World Vegan month, New Standards , Vegan, Conscious
Designer Payal Singhal launched her first ever shop in New Delhi at Aza, Ambawatta One, Mehrauli. At this new location, she also unveiled "Suroor" her Winter Festive' 2021 collection for Women that stays true to the brand's DNA of deconstructing and reimagining traditional Indian silhouettes for the modern aesthete.
The collection is replete with hybrid lehenga with cut-outs, sharara sets, kaftan kurtas and anarkalis; all enhanced with intricate mukaish, zardozi, gota, nakshi, pitta and mirror work. Statement yokes, the latest take on the House's signature back-tie choli, and a new burst of #PSPrints are also an integral part of the collection. For the first time, Payal has worked with bandhanis developed in Jaipur, but with her inimitable twist - using the technique on tussar instead of silks. (IANS/ MBI)
Keywords: Winter, Suroor, New Delhi, Designer, Payal Singhal, shop