Wednesday November 20, 2019

Thyroid Dysfunction May Lead to Diabetes During Pregnancy

Thyroid dysfunction in pregnancy linked to diabetes risk

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Pregnancy, air pollution
Sleeping for long hours during pregnancy linked to stillbirths. Pixabay

Thyroid dysfunction during the first half of pregnancy may indicate an increased risk for gestational diabetes — a form of diabetes that is typically diagnosed during the second trimester.

High thyroid hormone levels during pregnancy is also tied to increased the risk of premature delivery.

The researchers also warned that after birth, it may also cause the baby to develop conditions like hypoglycemia — low blood sugar — which can be dangerous if not treated correctly.

Representational image.
Representational image. Pixabay

“Our study found that women with thyroid abnormalities in the first half of pregnancy are at an increased risk for gestational diabetes, a common pregnancy complication that can cause short and long-term health problems for women and their children,” said senior study author Cuilin Zhang of the National Institute of Child Health and Human Development in Rockville, part of the US National Institutes of Health.

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In the study, published in the Journal of Clinical Endocrinology and Metabolism, the team examined medical records of 107 women with gestational diabetes and 214 other pregnant women.

“These findings, in combination with previous evidence of thyroid-related adverse pregnancy outcomes, support the benefits of thyroid screening among pregnant women in early to mid-pregnancy,” Zhang explained. (IANS)

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Study Says, Early Signs of Diabetes Can be Observed in Children

The study tracked over 4,000 participants of the Children of the 90s study, a birth cohort established in Bristol in the early 1990s

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Diabetes
The research was conducted among young healthy people who were generally free of type 2 Diabetes and other chronic diseases to see how early in life the effects of diabetes susceptibility become visible. Pixabay

Researchers have found that early signs of adulthood type 2 Diabetes can be seen in children as young as 8 years old.

Type 2 diabetes is most often diagnosed in middle age or later, with its symptoms slowly developing over many years.

“It’s remarkable that we can see signs of adult diabetes in the blood from such a young age, this is about 50 years before it’s commonly diagnosed.

“This is not a clinical study; nearly all participants were free of diabetes and most will not go on to develop it. This is about liability to disease and how genetics can tell us something about how the disease develops,” said study researcher Joshua Bell from the University of Bristol in the UK.

The research was conducted among young healthy people who were generally free of type 2 diabetes and other chronic diseases to see how early in life the effects of diabetes susceptibility become visible.

The study tracked over 4,000 participants of the Children of the 90s study, a birth cohort established in Bristol in the early 1990s.

The researchers combined genetics with an approach called ‘metabolomics’, which involves measuring many small molecules in a blood sample to try and identify patterns that are unique to type 2 diabetes.

According to the findings, the research team analysed 162 pieces of genetic information and combined this with 200 measures of many small molecules in a blood sample, known as metabolics, to identify signs of type 2 diabetes.

Diabetes
Researchers have found that early signs of adulthood type 2 Diabetes can be seen in children as young as 8 years old. Pixabay

Data was taken once in childhood — at 8 years old, twice in adolescence aged 16 and 18 years and once in young adulthood aged 25 years.

They found levels of HDL cholesterol were reduced at age 8, while inflammatory glycoprotein acetyls and amino acids were elevated in 16 and 18 year old teenagers.

These metabolic features could be targeted to prevent young people from going on to develop type 2 diabetes in the future, the researchers said.

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The findings were presented at the European Association for the Study of Diabetes (EASD) Annual Meeting in Barcelona. (IANS)