Tuesday December 10, 2019

Treating Diabetes May Also Prevent People From Developing Alzheimer’s Disease: Study

In addition, nearly 530 participants had normal blood sugar levels while 250 had prediabetes

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In Alzheimer's disease, patients start losing memory. Pixabay

Treating Type-2 diabetes may prevent people from developing Alzheimer’s disease, says a new study.

Patients with untreated diabetes develop signs of Alzheimer’s disease 1.6 times faster than people who did not have diabetes, according to the study published in the journal Diabetes Care.

Scientists consider Alzheimer’s as the result of a cascade of multiple problems including factors ranging from pollution exposure and genetics to heart and metabolic diseases.

“It is possible that the medicines for treating diabetes might make a difference in the progression of brain degeneration,” said Daniel A. Nation, Associate Professor at University of Southern California.

“But it’s unclear how exactly those medications might slow or prevent the onset of Alzheimer’s disease, so that is something we need to investigate,” he added.

Cognitive Impairment
Alzheimer’s disease patient Isidora Tomaz, 82, sits in an armchair in her house in Lisbon, Portugal. It’s predicted that by 2050, 135 million Americans are going to suffer from mild cognitive impairment, a precursor of Alzheimer’s. VOA

For the study, the researchers analysed data on nearly 1,300 people aged 55 and older.

Data included biomarkers for diabetes and vascular disease, brain scans and a range of health indicators, including performance on memory tests.

Among 900 of those patients, more than 50 had Type-2 diabetes who did not receive any treatment, whereas nearly 70 were undergoing treatment.

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In addition, nearly 530 participants had normal blood sugar levels while 250 had prediabetes.

“Our findings emphasise the importance of catching diabetes or other metabolic diseases in adults as early as possible,” Nation said.

“Among people with diabetes, the difference in their rate of developing the signs of dementia and Alzheimer’s is clearly tied somehow to whether or not they are on medication for it,” he noted. (IANS)

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Intermittent Fasting Benefits Those at Risk for Diabetes: Study

Time-restricted eating benefits those at risk for diabetes

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Diabetes
People at risk of developing diabetes should practice intermittent fasting. Pixabay

Researchers have found that people who are at high risk of developing diabetes improved their health when they consumed all of their meals over a span of just 10 hours, or less over a period of 12 weeks.

The study published in the journal cell Metabolism, reported a form of intermittent fasting, called time-restricted eating, improved the health of study participants who had been diagnosed with metabolic syndrome.

Metabolic syndrome is the name for a group of risk factors, such as high blood pressure and cholesterol levels, that increase the risk for adverse health issues, from heart disease and diabetes to stroke.

The researchers from University of California in US, found that when participants restricted their eating to 10 hours or less over a period of 12 weeks, they lost weight, reduced abdominal fat, lowered blood pressure and cholesterol and enjoyed more stable blood sugar and insulin levels.

Diabetes risks
Time-restricted eating can improve the health of those with diabetes. Pixabay

“Time-restricted eating is a simple dietary intervention to incorporate, and we found that participants were able to keep the eating schedule,” said study co-author Satchin Panda from the University of California in US.

“Eating and drinking everything (except water) during a 10-hour window allows your body to rest and restore for 14 hours at night. Your body can also anticipate when you will eat, so it can prepare the body to optimize metabolism,” Panda added.

Time-restricted eating (eating all calories within a consistent 10-hour window) allows individuals to eat in a manner that supports their circadian rhythms and their health.

Circadian rhythms are the 24-hour cycles of biological processes that affect nearly every cell in the body.

Erratic eating patterns can disrupt this system and induce symptoms of metabolic syndrome, including increased abdominal fat and abnormal cholesterol or triglycerides.

The study involved 19 participants diagnosed with metabolic syndrome, with 16 taking at least one medication, like a statin.

Diabetes risk factor
Metabolic syndrome is the name for a group of risk factors that includes diabetes. Pixabay

Participants used an app created by Panda called myCircadianClock to log when and what they ate during an initial two-week baseline period followed by three months of 10-hour time-restricted eating per day.

They were told they could decide what time to eat and how much to eat as long as all food consumption occurred within a 10-hour window.

At the end of the 12 weeks, participants averaged a three per cent reduction in weight and body mass index (BMI) and a four per cent reduction in abdominal/visceral fat.

Many also experienced reductions in cholesterol and blood pressure and improvements in fasting glucose. Seventy percent of participants reported an increase in sleep satisfaction or in the amount they slept.

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“Patients also reported that they generally had more energy, and some were able to have their medications lowered or stopped after completing the study,” said study researcher Pam Taub from University of California. (IANS)