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Turmeric inspires discovery of anti-cancer molecules

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source: myelomacrowd.org

Bhopal: A state-run university in Bhopal discovered anti-cancer molecules after being inspired by the healing properties of turmeric, which have been tried and tested for generations. This breakthrough is a revolutionary way forward in cancer treatment.

The Rajiv Gandhi Proudyogiki Vishwavidyalaya (RGPV) has also applied for a US patent of the discovery of the anti-cancer molecules code-named CTR-17 and CTR-20, informed Vice Chancellor Piyush Trivedi and his doctoral student Dr C Karthikeyan to news agencies on Monday.

“Inspired by the healing properties of turmeric, which is available in every household and considered as an effective antiseptic and given almost to everyone for treating various ailments, we have studied it deeply for almost 10 long years and discovered a molecule based on our findings which has magical effects on treating cancer during pre-clinical trials,” said Trivedi.

He added that this molecule only targets cancerous cells without damaging the others. So, unlike chemotherapy, the process had no side effects.

“The molecules code named CTR-17 and CTR-20 elicits anticancer activity through a mechanism which involves obstruction of cancer cell division by inhibition of tubulin, a protein which is important for many important cellular functions, including chromosome segregation during cell division, intracellular transport, development and maintenance of cell shape, cell motility and distribution of molecules on cell membranes,” explained Karthikeyan, who was a part of the research since the beginning.

Trivedi added that 22 other molecules had also been discovered, which produced good results in clinical trials, and would be a blessing for cancer patients.

The research was carried out in collaboration with Canada-based Advanced Medical Research Institute’s Dr Hyoun Lee’s team. After pre-clinical trials, the clinical trials are also slated to be held there on mice.

“Studies in the lab have also showed that CTR-17 and CTR-20 increased the life span of animals affected with tumour manifold by including tumour regression in mice models without showing any long-term adverse effects, especially less toxicity,” said Trivedi.

Furthermore, if combined with another anti-cancer drug in clinical use – ‘paclitaxel’, a strong synergistic effect is seen. Alone or combined, the molecules have shown strong anti-tumour activity.

“This is a significant discovery especially in the present context when cancer has become world’s dreaded killer disease accounting for 8.2 million deaths (around 13 per cent of all deaths) in 2012 as per the World Cancer Report and scientists embattling cancer are on the lookout for newer effective and safer drugs for anticancer therapy,” Trivedi added.

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Turmeric: The Magical Ingredient That Boosts Immunity

Boost your immunity with turmeric

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Here are some health issues and how turmeric can keep them at bay. Pixabay

BY ADITI ROY

Health is the biggest wealth in everyone’s life, even more so during the present unforeseen times when we are grappling with the deadly Coronavirus attack.

“Immunity” is the body’s natural defence against disease-causing bacteria and virus which can considerably reduce the odds of getting sick. It is only due to the weak immunity that people are getting affected with the widespread coronavirus and other such pandemics.

So, to fortify our immune system, we should look into the ancient wisdom of our Indian kitchen and what a better way than to fall back to good-old turmeric, which is loaded with anti-inflammatory, antiseptic and anti-bacterial properties due to the presence of curcumin. Add it to your food while cooking, temper your favourite curry with it or simply add a dash to make yourself a glorious golden milk.

“Curcumin has known immune system modulation properties and it alters immune response so as to avoid hypersensitivity reaction. Bronchial problems actually result from the hypersensitive reaction of the immune system and Curcumin helps balance these reactions – proves to be a fast relief,” explains Dr Saurabh Arora, inventor of SNEC30, Arbro Pharmaceuticals.

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Turmeric is loaded with anti-inflammatory, antiseptic and anti-bacterial properties due to the presence of curcumin. Pixabay

Turmeric aids in making our immunity stronger, the main life-saving ingredient in turmeric is about 3-5 % of Curcumin; a phyto-derivative, which contains healing properties. This ingredient can helo you lead a healthy lifestyle. Here are some health issues and how turmeric can keep them at bay:

Cough and Cold – As the temperature changes from cold to warm, it is very common for individuals to catch a common cold or flu. Turmeric helps the body naturally cleanse the respiratory tract, Turmeric helps fight the infection and it’s anti-inflammatory qualities relieve individuals from the direct impact of cold and flu.

Respiratory Ailments – People having bronchial problems like Sinsuits, Sinus and many faces a lot of problems due to lower immunity. Curcumin can be helpful in facing such problems and building up the immunity so that there should not be such kind of respiration Problems.

Upper Respiratory Tract Problems – Symptoms results in bronchial asthma, congestion of nose and airway due to inflammation, cough, cold and occasionally, shortness of breath, affecting children, adults, and elderly population. Inflammation constricts the airways and makes it difficult to breathe. This is often related to an exaggerated response by the immune system that leads to chronic inflammation and damage to lung tissue by free radicals. Curcumin inhibits inflammation, relieves congestion and pain and thus improves your breathing.

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Turmeric helps fight the infection and it’s anti-inflammatory qualities relieve individuals from the direct impact of cold and flu. Pixabay

Viral Replication – Curcumin helps in boosting up the immunity and helps to fight against viral replication of a disease which may have an incubation period ranging from 1 or 2 days to years.

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Reduces Inflammation – Curcumin suppresses various inflammatory molecules which are responsible for the causes of the damage caused by viruses. It helps in reduces symptoms and provides relief.

Inhibit Viral Replication – Exhibits all the antiviral properties by reducing the replication of the virus. Curcumin hence reduces the viral load. (IANS)