Wednesday August 22, 2018

Two-part Ebola vaccine may offer protection for a year against the deadly disease

An immune response was induced by the vaccine that persisted for approximately one year in volunteers according to results from the phase-1 clinical trial

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FILE - A health worker, center, takes the temperature of people to see if they might be infected by the Ebola virus inside the Ignace Deen government hospital in Conakry, Guinea, March 18, 2016. VOA
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New York, March 15, 2017: A two-part Ebola vaccine regimen has been found to offer protection against the deadly disease for about a year in an early human trial.

The vaccine regimen induced an immune response that persisted for approximately one year in healthy adult volunteers, according to results from the phase-1 clinical trial published in the Journal of the American Medical Association.

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The experimental vaccines included Ad26.ZEBOV, developed by Johnson & Johnson, and MVA-BN-Filo, developed by Denmark-based Bavarian Nordic.

Both of the vaccines in the regimen use harmless viral vectors, or carriers, to deliver proteins of the Ebola virus, which prompt an immune response.

The trial, conducted by Matthew D. Snape of the University of Oxford and colleagues, enrolled healthy participants aged 18-50 years in Britain.

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Participants were selected randomly to receive either the two-vaccine regimen or placebo (saltwater injections).

Previously reported initial results showed the two-vaccine regimen is safe, well-tolerated and induced immune responses in participants eight months after immunisation.

Of the 75 participants who received the vaccine regimen, 64 remained in the study for a follow-up visit on day 360.

No serious vaccine-associated adverse events were observed, and all 64 participants maintained antibodies to Ebola virus at day 360.

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The researchers noted that additional research is necessary to assess the durability of immunity beyond one year and the immune response to booster doses of vaccine. (IANS)

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USA: Everything you want to know about Security Clearance; Find out here!

A security clearance allows a person access to classified national security information or restricted areas.

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Former CIA Director John O. Brennan speaks at the Council on Foreign Relations in Washington, March 11, 2014. President Donald Trump revoked Brennan's security clearance Wednesday. VOA
Former CIA Director John O. Brennan speaks at the Council on Foreign Relations in Washington, March 11, 2014. President Donald Trump revoked Brennan's security clearance Wednesday. VOA

U.S. President Donald Trump on Wednesday revoked the security clearance of former CIA Director John Brennan. We take a look at what that means.

What is a security clearance?

A security clearance allows a person access to classified national security information or restricted areas after completion of a background check. The clearance by itself does not guarantee unlimited access. The agency seeking the clearance must determine what specific area of information the person needs to access.

What are the different levels of security clearance?

There are three levels: Confidential, secret and top secret. Security clearances don’t expire. But, top secret clearances are reinvestigated every five years, secret clearances every 10 years and confidential clearances every 15 years.

All federal agencies follow a list of 13 potential justifications for revoking or denying a clearance. VOA
All federal agencies follow a list of 13 potential justifications for revoking or denying a clearance. VOA

Who has security clearances?

According to a Government Accountability Office report released last year, about 4.2 million people had a security clearance as of 2015, they included military personnel, civil servants, and government contractors.

Why does one need a security clearance in retirement?

Retired senior intelligence officials and military officers need their security clearances in case they are called to consult on sensitive issues.

Also Read: Governments Across The World Request Apple for 30,000 Device Information

Can the president revoke a security clearance?

Apparently. But there is no precedent for a president revoking someone’s security clearance. A security clearance is usually revoked by the agency that sought it for an employee or contractor. All federal agencies follow a list of 13 potential justifications for revoking or denying a clearance, which can include criminal acts, lack of allegiance to the United States, behavior or situation that could compromise an individual and security violations. (VOA)