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An experimental vaccine proved 50% effective at preventing latent tuberculosis infection from turning into active disease in a three-year study of adults in Africa.
Doctors were encouraged because protection declined only a little after two years, and even a partially effective vaccine would be a big help against TB. The lung disease kills more than a million people a year, mostly in poor countries, and about one-third of the world’s people harbor the bacteria that cause it.
Results were reported Tuesday at a conference in India, the country hardest hit by TB, and published by the New England Journal of Medicine.
There is a TB vaccine now, but it’s given only to very young children and partly prevents severe complications. Researchers have been seeking a vaccine that also works in adults, to curb spread of the disease.
GlaxoSmithKline’s experimental vaccine was tested in nearly 3,600 adults in Kenya, South Africa and Zambia who were infected with TB but who did not also have HIV, the virus that causes AIDS.
Half were given two doses of vaccine a month apart and the rest got dummy shots. Thirteen people in the vaccine group and 26 in the other group developed active TB.
The new results show that “the vaccine is holding up” over time, and mark an important step toward having a prevention tool that’s been sought for 100 years, said Dr. Paula Fujiwara, scientific director of the International Union Against Tuberculosis and Lung Disease, the group hosting the conference in Hyderabad, India.
Plans are underway for another, definitive study, which will take at least several more years, she said.
After two-year results were announced last year, the World Health Organization called the vaccine a major breakthrough and has been holding meetings to discuss how to further its development. (VOA)
Fashion's biggest extravaganza, The Met Gala 2021, made a comeback with a vengeance after a skip in 2020 due to the pandemic. The theme for this year's gala was 'In America: A Lexicon of Fashion', and as usual in attendance were a long list of celebrities including actors, musicians and sportpersons. Many fashion houses and celebrities chose to dazzle with the dark side of fashion as capes, leather, face masks and all kinds of drama unfolded at the event, as black ruling the red carpet with its darker vibe.
Met Gala regulars like Jennifer Lopez, Rihanna, Sharon Stone, Emily Blunt, Irina Shayk, Gigi Hadid and the Kardashian-Jenner siblings were spotted alongside debutantes like 18-year-old British tennis star Emma Raducanu who recently won the US Open, Rose Leslie from 'The Game of Thrones', gymnast Nia Dennis and Justin and Hailey Beiber who walked the Me carpet together for the first time.
The event is hosted by Vogue's Dame Anna Wintour and is held annually at The Metropolitan Museum of Modern Art in New York City. Here's a look at some of the stars who chose to walk on the darker side:
The event is hosted by Vogue's Dame Anna Wintour and is held annually at The Metropolitan Museum of Modern Art in New York City. | IANS
Keywords: Jennifer Lopez, Rihanna, Sharon Stone, Emily Blunt, Irina Shayk, Gigi Hadid, the Kardashian-Jenner, Emma Raducanu, Met Gala
Luke Coutinho, Holistic Lifestyle Coach -- Integrative and Lifestyle Medicine shares an input that could prevent heart attacks at a young age:
Cholesterol is not the culprit, inflammation is: Many people believe that high levels of cholesterol and triglycerides are the sole culprits behind their heart attacks. The main reasons behind most heart attacks are inflammation and oxidative damage in the heart, blood vessels, endothelial lining, arteries, and more. While maintaining healthy cholesterol levels is important, we cannot blame heart attacks on cholesterol levels alone. What then can you do to keep inflammation in check and your heart strong? Adopt simple lifestyle changes.
Fix your sleep routine: There is nothing cool about pulling an all-nighter to work or socialize more. Your body only cares about survival. Remember, your sleep is your heart's free drug. The chronic deprivation of it can increase your risk of a heart attack. Your heart is a muscle that needs recovery. Lack of sleep increases your insulin resistance and makes you more prone to type-2 diabetes and a gamut of metabolic conditions. So, adopt a fixed sleeping schedule and sleep deep.
We cannot wait for more misfortunate incidents to realize the importance of lifestyle and start prioritizing it. We must wake up and work towards prevention. Many of us may go through heart disease later in life, no matter how well we exercise or eat clean. So, identify risk factors and work towards tackling them. Even if one of your risk factors is genetic predisposition and there is nothing you can do about it, you can still alter your lifestyle. Our intelligent human body was designed to fix and heal itself. The least we can do is invest in it and help it do its job effectively. Lifestyle can help you bridge this gap.
(Article originally written by: N. Lothungbeni Humtsoe) (IANS/ MBI)
Keywords: lifestyle, heart, oil, stress, sleep, human, body, health, heart attack
The fast food giant collaborated with local Indian suppliers and pioneered the local production of iceberg lettuce in the country. Their lettuce undergoes 30 quality and food safety checks. After harvesting, the lettuce is pre-cooled to a temperate of below 40C at the farm gate to maintain its freshness. It is then transported in refrigerated vehicles to the world-class processing plant where it is shredded to a measured length and width and then washed and cleaned thoroughly before being vacuum-packed.
Today, the lettuce that goes into your favourite burger is produced at a pristine height of 10,000 feet under the rain shadow areas of the Himalayas in the Manali and Lahaul districts. Over the last 15 years, the farm base that produces lettuce for McDonald's menu items has grown from 5 acres to more than 100 acres. The process for growing lettuce is very rigorous and thoroughly monitored starting with the selection of seed variety, nursery production, fertigation, integrated pest management and post-harvest technology. Over the years, the company has continued to engage with local suppliers in good agricultural practices, meeting the Gold Standards of food safety and hygiene. It has transferred global best practices in irrigation, pest control, seed selection benefitting nearly 250 small and marginal farmers across the country. These practices ensure the right conditions for the iceberg lettuce to grow.
(Article originally published on IANSlife) (IANS/ MBI)
Keywords: burger, india, lettuce, McDonalds, locals, North, East