Never miss a story

Get subscribed to our newsletter


×
Species-specific transcriptomes are fine-tuned by endogenous retroviruses in the mammalian germline. Pexels

As the world scrambles to control the growing Covid-19 pandemic, a new study shows viruses also play a key evolutionary role in mammals’ ability to reproduce and survive.

According to the study, published in the journal Nature Structural & Molecular Biology, scientists in the Cincinnati Children’s Perinatal Institute (CCPI) and at Azabu University in Japan obtained their data by studying laboratory mice and human germline cells.


Follow NewsGram on Twitter to stay updated about the World news.

In two separate papers appearing in the same edition of the journal, they revealed two distinct and fundamental processes underlying germline transcriptomes. They also show that species-specific transcriptomes are fine-tuned by endogenous retroviruses in the mammalian germline.

Want to read more in Hindi? Checkout: यूजर्स के डेटा संग छेड़छाड़ के लिए ट्विटर पर लगा 25 करोड़ डॉलर का जुर्माना

Germline transcriptomes include all the messenger RNA in germline cells, which contain either the male or female half of chromosomes passed on as inherited genetic material to offspring when species mate. This means that germline transcriptomes define the unique character of sperm and egg to prepare for the next generation of life.


The study, combined biological testing of mouse models and human germline cells with computational biology. Pexels

“Although the studies are separate they complement one another. One paper explores super-enhancers, which are robust and evolutionally conserved gene regulatory elements in the genome,”

said study researcher Satoshi Namekawa of CCPI.

They fuel a tightly regulated burst of essential germline genes as sperm start to form,” Namekawa added.The second study involves endogenous retroviruses that act as another type of enhancer – gene regulatory elements in the genome – to drive the expression of newly evolved genes. This helps fine-tune species-specific transcriptomes in mammals like humans, mice, and so on, the ream said.

Also Read: Singer Dhvani Bhanushali Missed Performing During Lockdown

The study, combined biological testing of mouse models and human germline cells with computational biology, including genome-wide profiling of gene regulatory elements in germline cells.Those tests revealed that the genome-wide reorganisation of super-enhancers drives bursts of germline gene expression after germ cells enter meiosis, a specialised form of cell division that produces the haploid genome of germ cells.The study further demonstrated the molecular process through which super-enhancer switching takes place in germ cells.

Super-enhancers are regulated by two molecules that act as gene-burst control switches – the transcription factor A-MYB and SCML2, a critical silencing protein in sperm formation, according to the team.”What we learn from our study is that, in general, viruses have major roles in driving evolution. In the long-term, viruses have positive impacts on our genome and shape evolution,” Namekawa explained. (IANS)


Popular

Photo by Pedro Durigan on Unsplash

The world's largest producer of ketchup announced the Packet Roller, a ketchup bottle-shaped gadget that allows users to squeeze the most out of a condiment packet, CNN reported.

Heinz has just rolled out a new product that the condiment company says is the "biggest innovation in sauce since the packet itself." Earlier this month, the world's largest producer of ketchup announced the Packet Roller, a ketchup bottle-shaped gadget that allows users to squeeze the most out of a condiment packet, CNN reported.

"Do not click 'purchase' unless you are prepared to change everything about the way you sauce," the Heinz Packet Roller website says. The roller goes for $5.70. The roller is pocket-sized, can be added to a keychain, and features a packet corner cutter.


Keep Reading Show less
Wikimedia Commons

Swiss tennis ace Roger Federer, is recovering from a right-knee surgery he underwent last month.

Swiss tennis ace Roger Federer, who is recovering from a right-knee surgery he underwent last month, said on Sunday that it was a difficult process to decide whether to undergo a third right-knee surgery after having two last year. But following Wimbledon, where he was "really unhappy" with his performance in reaching the quarterfinals, Federer opted to go through with it.

Federer, who made a late decision to attend this year's Laver Cup in Boston -- a tournament held between teams from Europe and the rest of the world -- said on the sidelines of the event that the recovery and rehabilitation are "going to take me a few more months and then we'll see how things are at some point next year". "The reception I've received, everybody is so upbeat that I'm here. They wish me all the best and they don't even see the crutches. They just want me to be good again and enjoy the weekend," Federer said in an interview for the event with former world No. 1 Jim Courier.

"I've seen some incredible tennis, some great matches and it's been wonderful. I'm really happy I made the trip," the winner of 20 majors was quoted as saying by atptour.com. On why he opted for a third surgery, the tennis ace said, "I was just nowhere near where I wanted to be to play at the top, top level. But I tried my best and at the end... too much is too much. Now I've just got to take it step by step," Federer said.

Roger Federer RG2012 volley Federer received thunderous ovations inside Boston's TD Garden, where he has often been sitting in the front row watching the action or behind the scenes visiting with the players. | Wikimedia Commons

Keep Reading Show less
Photo by Eiliv-Sonas Aceron on Unsplash

By Hitesh Rathi

Cleopatra, was regarded as a great beauty, to preserve her skin, she took her daily bath in donkey milk. Besides, Hippocrates, the father of medicine, prescribed donkey milk for various diseases including fever, wounds, etc. To add to these benefits, donkey milk has four times the amount of Vitamin C than cow's milk has. So, it's no secret that donkey milk is a powerhouse of nutrients for both the skin and body.

Used for Anti-Ageing and Healing
The milk contains essential fatty acids that work as powerful anti-ageing and healing properties. These fatty acids blur the wrinkles on the skin and help to regenerate damaged skin. Plus, donkey milk also contains anti-bacterial properties which are effective in healing skin irritation and redness.

Look younger as you get old The milk contains essential fatty acids that work as powerful anti-ageing and healing properties.| Flickr

Keep reading... Show less