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Intake of Vitamin b3 can help in reducing the risk of Skin cancers. Pixabay

A form of vitamin B3 can protect skin cells from the effects of ultraviolet (UV) exposure which is the main risk factor for non-melanoma skin cancers, reveals new research.

Researchers in Italy isolated cells (human primary keratinocytes) from the skin of patients with non-melanoma skin cancers.


These cells were treated with three different concentrations of nicotinamide (NAM) — a form of vitamin B3 — for 18, 24, and 48 hours and then exposed to UVB.

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Results showed that pre-treatment with 25 microns (M) of NAM 24 hours before UV irradiation protected the skin cells from the effects of UV-induced oxidative stress, including DNA damage.

NAM enhanced DNA repair, demonstrated by decreased expression of the DNA repair enzyme OGG1.

Furthermore, it decreased antioxidant expression and blocked local inflammation by showing decreased nitric oxide (NO) release and reactive oxygen species (ROS) production and reduced iNOS protein expression.


Vitamin B3 food. Flickr

“Our study indicates that increasing the consumption of vitamin B3, which is readily available in the daily diet, will protect the skin from some of the effects of UV exposure, potentially reducing the incidence of non-melanoma skin cancers,” said Lara Camillo, a research student from the dermatological unit of AOU Maggiore della Carita, Novara, Italy.

However, the protective effect of vitamin B3 is short-acting, so it should be consumed no later than 24 to 48 hours before sun exposure, she said during the 29th European Academy of Dermatology and Venereology virtual conference.

ALSO READ: Natural Antioxidants Keep Heart Healthy During COVID and Winter

Non-melanoma skin cancers are the most common malignancies and are increasing worldwide.

The main risk factor is UV radiation exposure, which damages the DNA, increases ROS production, activates local inflammation, and depletes cellular energy, leading to genomic instability and cell death. (IANS)


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Delhi to get new QR-based driving livenses and registration certificates.

In a step towards digitisation of the system, Delhi Transport Department will soon issue QR based Smart cards for driving licenses (DLs) and registration certificates (RCs).

As per a statement, the new driving licence will have an advanced microchip with features like Quick Response (QR) code and Near Field Communication (NFC). The new RC will have the owner's name printed on the front while the microchip and the QR code would be embedded at the back of the card.

The cards earlier had embedded chips, but chip reader machines were not available in the required quantity with both the Delhi Traffic Police and the Enforcement Wing of the Transport Department. Moreover, chips were designed and implemented by the states concerned, which resulted in difficulties in reading the chip and retrieving information, especially in case of defaulters.

"Now with the QR based smart card, this issue is resolved. This will enable unification in linking and validating one's information to smart cards with Sarathi and Vahan, the two web-based databases of all driving licenses and vehicle registrations," the release added.

The QR is also being implemented nationwide, the QR code reader is easily procurable and will do away with the requirement of any manual intervention altogether. The new cards will also allow two specific materials for their card manufacturing -- PolyVinyl Chloride or PVC, or PolyCarbonate which is slightly more expensive but more durable. (Card Size - 85.6mm x 54.02 mm; Thickness minimum 0.7 mm)

An October 2018 notification of the Ministry of Road Transport and Highways (MoRTH) had made changes to the Driving License and Registration Certificate. The new Smart card based DL and RC, will have chip based/ QR code based recognition system. At the same time, documents such as driving license or registration certificates in electronic formats on DigiLockers and mParivahan were also made valid in place of physical documents and treated at par with original documents.

The QR code also has an added advantage of acting as a safety feature on the smart card. The department will be able to retain records and penalties of the DL holder for up to 10 years on the VAHAN database as soon as a driver/ owner's Smart card is confiscated. The new DLs will also help the government in maintaining records of differently-abled drivers, any modifications made to the vehicles, emission standards and the person's declaration to donate organs. (IANS/JB)

Keywords: Delhi, Driving License, Registration License, Digitisation.