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TB is the leading killer of HIV-infected people. In South Africa, 73% of TB patients are HIV positive. Pixabay

Foods rich in Vitamin C (such as dark leafy greens, broccoli, kiwifruit and oranges) can enhance treatment and enable a faster recovery for people suffering from tuberculosis (TB), if taken along with regular medication.

TB is one of the world’s deadliest diseases, with one third of the global population infected. In 2016, it affected 10.4 million people around the world and caused 1.7 million deaths.



Vitamin C helps treating TB. Pexels

Findings

  • Giving Vitamin C — a powerful antioxidant that reduces oxidative stress to the body and also lowers cancer risk — with TB drugs could reduce the unusually long time it takes these drugs to eradicate this pathogen.
  • The addition of Vitamin C to TB drug treatment potentiates the killing of bacterium Mycobacterium tuberculosis (MTB) and could shorten TB chemotherapy.
  • That’s important because treatment of drug susceptible TB takes six months, resulting in some treatment mismanagement, potentially leading to the emergence and spread of drug-resistant TB.

Vitamin C had no activity by itself, but in two independent experiments, the combination of Vitamin C with the first-line TB drugs, isoniazid and rifampicin, reduced the organ burdens faster than the two drugs without vitamin C, said Catherine J. Vilcheze, at the varsity.

“Vitamin C is known to be safe and our current mouse studies suggest that Vitamin C could enhance TB chemotherapy,” said lead investigator William R. Jacobs, from the Albert Einstein College of Medicine in New York.


TB is one of the world’s deadliest diseases, with one third of the global population infected. Wikimedia commons

Methodology

  • The team treated MTB-infected mice with anti-TB drugs or vitamin C alone, or the drugs and vitamin C together.
  • Experiments in infected tissue cultures demonstrated similar results, shortening the time to sterilisation of the tissue culture by seven days.

The study was published in the journal Antimicrobial Agents and Chemotherapy. (IANS)


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"In the early 60s when I arrived in Delhi, it was a quiet and safe place. There were villages within the city. After seeing a late night movie at the Race Course theatre, women and children would walk down to Lodhi Colony past midnight. No woman was harmed. "In summer, we used to sleep on the charpoys spread out on the terraces of our houses without locking the main house door down below. It was a city anybody will dream of living. And then Delhi changed all of a sudden - a brutal, grotesque change. "Factories and commercial establishments came up, attracting unemployed poor people from other states. Building mafias destroyed villages and fields and built ugly high-rise buildings. Poor people were pushed away to filthy slums where they led a wretched life of deprivation. Throwing away all values, a nouveau riche class prospered. Outwardly, Delhi is a beautiful city. But beneath lies hunger, filth and diseases," Mukundan elaborated.

Mukundan A Soliloquy" is the story of the changes and growth of the city with Sahadevan's life as the backdrop. Wikimedia Commons

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