Saturday May 26, 2018

Study: Vitamin D can helpful in Recovery from Burn Injuries

Researchers have found that Vitamin D can help in Recovering from Burn Injuries.

0
//
48
role of Vitamin D in recovery from burn injuries
Vitamin D capsules. Pixabay
Republish
Reprint
  • Patients with severe burns who have higher levels of Vitamin D recover more successfully than those with lower levels, researchers claimed to have found.

Vitamin D supplementation is Cost-effective treatment for Burn Patients

A study that is claimed to be the first to investigate the role of Vitamin D in recovery from burn injuries suggests that Vitamin D supplementation may be a simple and cost-effective treatment to enhance burn healing, the researchers said.

“Major burn injury severely reduces Vitamin D levels and adding this vitamin back may be a simple, safe and cost-effective way to improve outcomes for burns patients, with minimal cost to NHS,” said Janet Lord, Professor at the Institute of Inflammation and Aging in Birmingham.

Vitamin D is known to have antibacterial actions that may help combat infection and therefore aid in wound healing of burn patients.

In order to investigate the role of Vitamin D in recovery from burn injuries, researchers assessed the recovery progress, over one year, in patients with severe burns and correlated this with their Vitamin D levels.

The study, presented at the Society for Endocrinology annual conference in Harrogate, found that patients with higher levels of Vitamin D had a better prognosis, with improved wound healing, fewer complications, and less scarring.

The data also showed that burns patients tend to have lower levels of Vitamin D.

These data suggest that Vitamin D supplementation immediately following burn injury may have potent health benefits to the patient, including enhanced antimicrobial activity to prevent infection, and improved wound healing, the researchers noted.( IANS)

Click here for reuse options!
Copyright 2017 NewsGram

Next Story

New Approach for Treating Diseases Like Diabetes and Cancer

Enhanced activation of Vitamin D by protecting beta cells may be a potential new approach for treating diabetes as well as other diseases, including cancer, researchers have suggested.

0
//
61
The researchers found that Vitamin D in cells and mouse models can be beneficial in treating these damaged beta cells.
Representational image, pixabay

Enhanced activation of Vitamin D by protecting beta cells may be a potential new approach for treating diabetes as well as other diseases, including cancer, researchers have suggested.

When beta cells — the cells in the pancreas that produce, store and release the hormone insulin — become dysfunctional, the body cannot make insulin to control blood sugar (glucose) and levels of glucose can rise to dangerous and even fatal levels.

The researchers found that Vitamin D in cells and mouse models can be beneficial in treating these damaged beta cells.

They also provided new insights about gene regulation that could be applied to developing treatments for other diseases, including cancer.

“We know that diabetes is a disease caused by inflammation. We identified the Vitamin D receptor as an important modulator of both inflammation and beta cell survival,” said Ronald Evans, from Salk Institute for Biological Studies in California, US.

Combining the new compound with vitamin D allowed certain protective genes to be expressed at much higher levels than they are in diseased cells.
Representational image, pixabay

Using beta cells created from embryonic stem cells, the team was able to identify a compound — iBRD9 — that appeared to enhance the activation of the Vitamin D receptor when it was combined with Vitamin D to improve the survival of beta cells.

In the paper, published in the journal Cell, the team conducted a screening test to look for compounds that improved the survival of beta cells in a dish. They then tested the combination in a mouse model of diabetes and showed that it could bring glucose back to normal levels in the animals.

Combining the new compound with vitamin D allowed certain protective genes to be expressed at much higher levels than they are in diseased cells.

“Activating the vitamin D receptor can trigger the anti-inflammatory function of genes to help cells survive under stressed conditions,” explained Michael Downes, from the institute.

Also Read: A Drug That Can Potentially Cure Hair Loss

The researchers noted that although the new compound did not appear to cause any side effects in the mice, further testing is needed before clinical trials can begin. (IANS)

Next Story