Saturday March 17, 2018

Want to Quit Smoking (Nicotine)?: Help is Here!

Cigarettes contain Nicotine which causes addiction

Nicotine addiction
E Cigarettes are not a solution to those who wish to quite smoking because E Cigarettes too contain Nicotine. Image credit:

Dr. M.v. Annalarasi

We at in the previous articles have emphasized the need to quit smoking. Like mentioned earlier, it is true that it is easier said than done. In this article, we would like to communicate to you, in case you already didn’t know, the various recommended practices to adapt while trying to quit smoking. Apart from our articles, you might have come across several sources of the ill effects of smoking. But try adapting a different perspective to look at this issue. The beneficial effects of quitting smoking are aplenty.

It is a common knowledge that nicotine is the addictive substance that keeps you glued to smoking. But to abolish it from your life immediately can have some unfavorable implications: Nicotine withdrawal symptoms are insomnia, anxiety, difficulty to concentrate, intense craving to get your hands-on nicotine, depression etc.

To help you avoid quit as well aid you in a smooth transition towards “ the life without nicotine”, nicotine replacement products are recommended. These products are designed in such a way that they supply nicotine in controlled amounts. This would prepare your physical being to cooperate with your mental efforts to quit. Also, some of these products function on the mechanism of positive reinforcement and desensitizing the nicotine receptors by the nicotine replacement. Some of these products are sold under prescription and some are available over the counter. These are Nicotine transdermal patches, lozenges, inhaler, nasal spray, and chewing gums.

The safety of ‘the otherwise effective nicotine replacement therapy’ during pregnancy, remains to be determined. Nicotine in any form still poses a threat to the fetus. If you are a pregnant woman or have been diagnosed with any health condition like asthma, COPD, diabetes, hypertension, it is advisable to better consult a physician before buying these products on your own.

  1. Nicotine (Transdermal) patches: recommended not to be used alongside cigarette smoking. It has the advantage of moderating and maintaining sustainable levels of nicotine ( lesser than in cigarettes).

 2Nasal spray: available as prescription-only drug and the dosage delivered is tapered over time.

3. Gum: a slow release resin containing nicotine and polacrilin. It has a proved smoking cessation track record of up to 70%. ( available over the counter).

Each of these substances come with their own side effects like sore throat, dry mouth, nausea, dyspepsia etc. But the effects are controlled over a period and hence signal safety with uncontested clarity.

4. Medications: There are some non-nicotine containing pharmacotherapeutic substances (FDA approved and primary line of management) that come to your aid in ‘the quit smoking movement’. Two common examples are Bupropion hydrochloride and Varenicline tartrateClonidine, an alpha-2 adrenergic receptor agonist, used for treating hypertension has also demonstrated considerable efficacy but not FDA approved. Yet, it has been endorsed by the US clinical practice guidelines to be prescribed as a second line of treatment for tobacco addiction. Next in line is Nortriptyline, a tricyclic antidepressant, primarily prescribed to treat depression. It has also exhibited potential as the second line of treatment. The research to make patches with this drug is still under process.

An alkaloid called cytisine binds to the nicotinic acetylcholine receptor and in some clinical studies has proved to be superior to the replacement therapy.

Some of these are available commercially and some are still in the process to reach approval. It is heartening to know that the efforts to help people trying to quit are on the rise. Check the approval status of the drugs on the regulatory websites of your country. It is even better to approach a physician to get yourself a medically accurate blueprint to quit smoking.

Did you know? Nicotine vaccines might also become a reality soon. This new line of immunotherapy for smoking cessation is also underway.


The harms due to tobacco will stay away from you if you stay away from tobacco.

The article first appeared at Same Condition website:

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Smoking during pregnancy linked to asthma severity in kids

Prenatal tobacco smoke exposure was associated with a 2.5 times increase in odds of having airflow obstruction in children with asthma

  • Smoking during pregnancy can be very dangerous
  • It can lead to asthma and poor lung function in the baby
  • It also can have serve effects on the health of the mother

Women who smoke while pregnant contribute to the severity of asthma and poor lung function in their children warns a study.

The findings published in the journal CHEST suggest that tobacco smoke exposure during pregnancy is more strongly associated with worse lung function than current, ongoing exposure in school-aged children with asthma.

Smoking during pregnancy can be unhealthy for the child.

“This study implicates maternal smoking in pregnancy as the period of second-hand exposure that is more strongly associated with worse lung function in asthmatic children,” said lead investigator Stacey-Ann Whittaker Brown from Icahn School of Medicine at Mount Sinai, New York.

“Maternal smoking in pregnancy may set children with asthma on a trajectory of poor lung function in later childhood, and other studies suggest this effect may be lifelong,” Whittaker Brown said.

Investigators analysed the relationship between lung function and the type of second-hand smoke exposure in a representative sample of school-aged children aged six to 11 years.

Also Read: Why you should avoid Paracetamol during pregnancy

The sample consisted of 2,070 children who participated in the 2007-2012 National Health and Nutrition Examination Survey (NHANES) in the US.

Detailed information about ongoing second-hand smoke exposure as well as parental self-reported exposure prior to birth was obtained.

During the study period, lung function was measured using spirometry, and exposure to smoking was assessed through levels of cotinine in the blood, a marker of the extent of current second-hand smoke exposure. Thus, investigators were able to distinguish clearly between exposure in pregnancy and ongoing second-hand smoke exposure.

Protein responsible for postpartum depression in pregnancy found
Smoking during pregnancy is very dangerous. IANS

Nearly 10 percent of both children with and without asthma in the sample had reduced lung function.

Investigators found that current tobacco smoke exposure was independently associated with airflow obstruction in school-aged children, although the extent of the association was small.

However, prenatal tobacco smoke exposure was associated with a 2.5 times increase in odds of having airflow obstruction in children with asthma, the study said. IANS