Monday June 25, 2018

Want to Quit Smoking (Nicotine)?: Help is Here!

Cigarettes contain Nicotine which causes addiction

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Nicotine addiction
E Cigarettes are not a solution to those who wish to quite smoking because E Cigarettes too contain Nicotine. Image credit: www.SameCondition.com
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Dr. M.v. Annalarasi

We at samecondition.com in the previous articles have emphasized the need to quit smoking. Like mentioned earlier, it is true that it is easier said than done. In this article, we would like to communicate to you, in case you already didn’t know, the various recommended practices to adapt while trying to quit smoking. Apart from our articles, you might have come across several sources of the ill effects of smoking. But try adapting a different perspective to look at this issue. The beneficial effects of quitting smoking are aplenty.

It is a common knowledge that nicotine is the addictive substance that keeps you glued to smoking. But to abolish it from your life immediately can have some unfavorable implications: Nicotine withdrawal symptoms are insomnia, anxiety, difficulty to concentrate, intense craving to get your hands-on nicotine, depression etc.

To help you avoid quit as well aid you in a smooth transition towards “ the life without nicotine”, nicotine replacement products are recommended. These products are designed in such a way that they supply nicotine in controlled amounts. This would prepare your physical being to cooperate with your mental efforts to quit. Also, some of these products function on the mechanism of positive reinforcement and desensitizing the nicotine receptors by the nicotine replacement. Some of these products are sold under prescription and some are available over the counter. These are Nicotine transdermal patches, lozenges, inhaler, nasal spray, and chewing gums.

The safety of ‘the otherwise effective nicotine replacement therapy’ during pregnancy, remains to be determined. Nicotine in any form still poses a threat to the fetus. If you are a pregnant woman or have been diagnosed with any health condition like asthma, COPD, diabetes, hypertension, it is advisable to better consult a physician before buying these products on your own.

  1. Nicotine (Transdermal) patches: recommended not to be used alongside cigarette smoking. It has the advantage of moderating and maintaining sustainable levels of nicotine ( lesser than in cigarettes).

 2Nasal spray: available as prescription-only drug and the dosage delivered is tapered over time.

3. Gum: a slow release resin containing nicotine and polacrilin. It has a proved smoking cessation track record of up to 70%. ( available over the counter).

Each of these substances come with their own side effects like sore throat, dry mouth, nausea, dyspepsia etc. But the effects are controlled over a period and hence signal safety with uncontested clarity.

4. Medications: There are some non-nicotine containing pharmacotherapeutic substances (FDA approved and primary line of management) that come to your aid in ‘the quit smoking movement’. Two common examples are Bupropion hydrochloride and Varenicline tartrateClonidine, an alpha-2 adrenergic receptor agonist, used for treating hypertension has also demonstrated considerable efficacy but not FDA approved. Yet, it has been endorsed by the US clinical practice guidelines to be prescribed as a second line of treatment for tobacco addiction. Next in line is Nortriptyline, a tricyclic antidepressant, primarily prescribed to treat depression. It has also exhibited potential as the second line of treatment. The research to make patches with this drug is still under process.

An alkaloid called cytisine binds to the nicotinic acetylcholine receptor and in some clinical studies has proved to be superior to the replacement therapy.

Some of these are available commercially and some are still in the process to reach approval. It is heartening to know that the efforts to help people trying to quit are on the rise. Check the approval status of the drugs on the regulatory websites of your country. It is even better to approach a physician to get yourself a medically accurate blueprint to quit smoking.

Did you know? Nicotine vaccines might also become a reality soon. This new line of immunotherapy for smoking cessation is also underway.

Remember:

The harms due to tobacco will stay away from you if you stay away from tobacco.

The article first appeared at Same Condition website: https://www.samecondition.com/blog/trying-quit-nicotine-dont-struggle-alone/

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Obesity And Smoking: Roadblocks In Arthritis Treatment

Rheumatoid arthritis is a chronic inflammatory disease

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Obesity And Smoking Becomes Roadblocks In Arthritis Treatment
Obesity And Smoking Becomes Roadblocks In Arthritis Treatment, Pixabay

Obesity in women and smoking among men could be major factors behind not achieving remission in rheumatoid arthritis, despite early treatment, researchers say.

Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability and can also affect internal organs.

The study showed that though early identification and aggressive treatment improve arthritis outcomes, six per cent of women and 38 per cent of men did not achieve remission in the first year despite receiving guideline-based care.

“Our results suggest that lifestyle changes — smoking cessation in men and weight reduction in women — as well as optimising methotrexate use may facilitate rapid reduction of inflammation, an essential goal of treatment in early rheumatoid arthritis,” said Susan Bartlett, professor of Medicine at McGill University in Canada.

The study, published in the journal Annals of the Rheumatic Diseases, included 1,628 adults with an average age of 55.

The analysis highlighted that obesity more than doubled the likelihood of not achieving remission in women.

obesity
obesity, Pixabay

In men, current smoking was associated with 3.5 greater odds of not achieving remission within the first year.

Further, almost all patients within the study were initially treated with conventional synthetic disease-modifying antirheumatic drugs (csDMARDs), with three quarters being treated with methotrexate.

Analysis demonstrated that not using methotrexate significantly increased the likelihood of not achieving remission in women by 28 per cent and in men by 45 per cent.

Also read: drug free compound can ease arthritis pain

“These results highlight the need to support physicians and empower patients to take advantage of the impact lifestyle changes can have on disease progression,” Johannes Bijlsma, President, European League Against Rheumatism (EULAR), said in a statement. (IANS)