Friday September 21, 2018

Weight Loss May Reverse Heart Rhythm Disorder

People who lost weight experienced fewer symptoms, required less treatment and had better outcomes

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Asthma may up obesity risk. Pixabay
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Losing weight may reverse or reduce the progression of irregular heart rhythm disorder among obese people, claim researchers, including one of Indian origin.

The findings showed that reducing weight by 10 per cent along with management of associated risk factors can reduce the effects of Atrial fibrillation (AF), a leading cause of stroke which can lead to heart failure among overweight people.

People who lost weight experienced fewer symptoms, required less treatment and had better outcomes.

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Stop Obesity. Pixabay

“This is the first time that evidence has been found that if people who are obese and are suffering from atrial fibrillation the disease can be alleviated by losing weight and treating lifestyle factors,” said lead author Melissa Middeldorp from the University of Adelaide in Australia.

AF is a progressive disease in which initial short, intermittent symptoms develop into more sustained forms of the condition. Obesity and lifestyle factors are associated with its progression.

Also Read: Overweight in Middle Age Linked to Low Breast Cancer Risk

“This study shows that weight-loss and treating lifestyle factors is an essential component for effectively managing AF, in many instances being an alternative to surgery or drug intervention,” added Professor Prashanthan Sanders from the varsity.

In the study, published in the journal Europace, the team analysed 355 overweight people who lost varying amounts of weight. (IANS)

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Weight Loss Tip- Chinese Medicine Ingredient May Help Reduce Obesity

Overweight and obesity may increase the risk of many health problems, including diabetes, heart diseases and certain cancers

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Weight Loss
The study, published in the journal Diabetes, observed a significantly altered eating behaviour in overweight animals. Pixabay

A herbal ingredient used in traditional Chinese medicines may help you to reduce your body weight, a new study has found.

The scientists were able to show that the herbal active substance, celastrol — used in Chinese medicines — leads to a significant weight loss and an improvement of diabetes in obese mice, Xinhua news agency reported on Saturday.

The findings showed the celastrol specifically activates satiety centres in the brain, which play a central role in the control of body weight.

“Normally, those affected lose their satiety because the corresponding hormone leptin no longer works. The drug celastrol we investigated restores leptin sensitivity and hence satiety,” said lead author Katrin Pfuhlmann from Helmholtz Zentrum Munchen – German Research Centre for Environmental Health.

The study, published in the journal Diabetes, observed a significantly altered eating behaviour in overweight animals.

Weight loss
Representational image. Pixabay

“The administration of celastrol resulted in significantly reduced food intake in the mouse model. Accordingly, we were able to determine an average loss of about 10 per cent body weight within a week,” the researchers said.

To what extent the findings can also be confirmed in humans is still unclear, according to the authors. However, study leader Pfluger is confident, “The satiety hormone leptin in humans and the mouse is almost identical, so celastrol has great potential,” the report said.

The clinical trials are currently under way in the US.

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“The satiety hormone leptin in humans and the mouse is almost identical, so celastrol has great potential,” the researcher said.

Overweight and obesity may increase the risk of many health problems, including diabetes, heart diseases and certain cancers. (IANS)

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