Sunday November 18, 2018

Weight Loss Surgery To Combat Womb Cancer in Obese Women

"But for those that choose it, gastric sleeve or bypass surgery can now be seen as a preventative measure for womb cancer."

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Breast Cancer
Early rising women at lower risk of breast cancer: Study. Pixabay
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Undergoing bariatric surgery to combat obesity can prevent women from developing womb cancer also known as uterine or endometrial cancer, claims a study.

The findings, led by scientists from the University of Manchester, showed that women who had gastric sleeve or bypass surgery for obesity found that precancerous tissue in their womb reverted to normal tissue when they lost weight.

“For super obese women, quick access to weight loss surgery has benefits beyond improving diabetes and risk of heart disease. It can also reduce womb cancer risk,” said Emma Crosbie, clinical senior lecturer from Manchester.

“Losing weight through dieting is also likely to be effective, but we know that dieting is very hard to do and weight lost is often re-gained,” she said.

In the study, published in International journal of Cancer, the team examined nearly 100 women with an average BMI of over 50 — considered to be super obese — had biopsies taken from their wombs during gastric sleeve or bypass surgery.

Obese post-menopausal women produce oestrogen from their fat stores. But as they no longer ovulate, the lack of progesterone allows the cells in the womb to grow, which increases the risk of cancer.

Cancer
Cancer Ribbon. Pixabay

Inflammatory responses and insulin production are also changed in obese women and can cause cells in the womb to grow.

“Because the reversal of precancerous changes in the womb was so quick, we think the metabolic consequences of weight loss surgery was crucial,” said Crosbie.

However, the researchers stressed that the surgical option was not for everyone, because it was no an easy choice.

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“It changes your relationship with food forever, as you’ll be eating smaller meals more frequently, and it is important to remember that surgery can be a hazardous procedure,” said Crosbie.

“But for those that choose it, gastric sleeve or bypass surgery can now be seen as a preventative measure for womb cancer.” (IANS)

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Losing Weight Can Help Lower The Risk of Breast Cancer For Post-menopausal Women

"These findings, taken together, provide strong correlative evidence that a modest weight loss programme can impact breast cancer,"

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Photo: neqotkukhealthcenter.ca

Women, please take a note. Losing weight can help lower the risk of developing breast cancer in the post-menopausal stage, a new study has found.

The study, published in the journal CANCER, found that among post-menopausal women, participants who lost weight had a lower risk of developing invasive breast cancer than those who maintained or gained weight.

“Our study indicates that moderate, relatively short-term weight reduction was associated with a statistically significant reduction in breast cancer risk for postmenopausal women,” said co-author Rowan Chlebowski from the City of Hope National Medical Center in Duarte, California.

Although obesity has been strongly related to breast cancer risk, studies examining whether weight loss might reduce postmenopausal women’s risk have provided mixed results, the researchers said.

For the study, the research team analysed information on 61,335 women participating in the World Health Initiative Observational Study who had no prior history of breast cancer and had normal mammogram results.

Breast Cancer
Weight loss may lower breast cancer risk for post-menopausal women. Pixabay

The participant’s body weight, height and body mass index were assessed at the start of the study and again three years later.

The team found that during an average follow-up of 11.4 years, there were 3,061 new cases of invasive breast cancer diagnosed.

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“These are observational results, but they are also supported by randomised clinical trial evidence from the Women’s Health Initiative Dietary Modification trial where, in a randomised clinical trial setting, adopting a low-fat dietary pattern that was associated with a similar magnitude of weight loss resulted in a significant improvement in breast cancer overall survival,” Chlebowski said.

“These findings, taken together, provide strong correlative evidence that a modest weight loss programme can impact breast cancer,” he noted. (IANS)