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As they wait for the Covid-19 vaccine continues, the battle rages on. Scores of people have tested positive for the novel Coronavirus, many have succumbed, and many more have recovered from the infection as well.
For those patients who successfully overcome the virus, social media is inundated with requests that they donate their plasma for Convalescent Plasma Therapy – a treatment considered to be beneficial to patients who have tested positive.
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‘Plasma’ is the liquid component in the blood that carries antibodies, hormones, and various nutrients across the body. Convalescent Plasma is the plasma collected from people who were infected and have made a complete recovery; these people develop antibodies that are of vital importance. Antibodies are proteins used by the body to fight off infections and thus provide immunity to those who have beaten Covid-19. The plasma of these patients is transfused into the blood of patients who are fighting Covid-19.
The therapy may be specifically beneficial to those who are extremely sick and haven’t responded to other treatments – often developing Acute Respiratory Distress Syndrome (ARDS), which may require ventilator support, informs Dr. Farah Ingale.
“While there isn’t sufficient data to back its efficacy, Convalescent Plasma Therapy is reported to help patients who are at higher risk, such as those with comorbidities like heart disease or diabetes, or those who have weakened immune systems,” stated Dr. Ingale, who is Director-Internal Medicine, Hiranandani Hospital Vashi, tells IANSlife.
WHAT ARE THE FUNCTIONS OF BLOOD PLASMA?
Antibodies once bound to the virus, neutralize it
The antibodies activate the pathways and help prevent further damage to cells
Reduces the overall viral load
Plasma transfused from at least two donors provides diverse antibodies, thus delivering greater protection to the immune system
HOW CAN YOU BECOME A PLASMA DONOR?
A donor must wait up to 14-28 days after full recovery before being approved to donate, the person must:
Not have fever
Not have any respiratory difficulties
Have normal oxygen levels i.e. between 95 percent and 100 percent
Have overall good health
At the time of infection, a valid and official diagnostic test must be done to confirm SARS-CoV
Undergo standard procedure to rule out HIV, Hepatitis B & C virus, etc.
Have two negative tests to SARS-CoV-2 at an interval of 24 hours on nasal swabs
HOW IS PLASMA COLLECTED?
Blood Plasma is collected through a procedure called Plasmapheresis which usually takes around 45minutes
During this procedure, blood is drawn and the plasma is separated; the blood cells and platelets are then returned to the donor
It can also be drawn from whole blood
Plasma is rather swiftly replenished in the body
The general volume of plasma to be collected is between 300ml to 600ml
Once the plasma is extracted, it is frozen at -18O C or colder within 24 hours of extraction. It can be stored for up to 12 months from the date of extraction
ARE REPEAT PLASMA DONATIONS DONE?
If a donor may wish to donate once again, if done previously by the Plasmapheresis method – he/ she should wait for about seven days
If whole blood was donated, the ideal wait time is around eight weeks before the next donation
It is important to note that the treatment is at an experimental stage and is not yet proven to be fully effective for Covid-19, the doctor concludes. (IANS)
India is known for its pickles, popularly called 'Achaar', even across the world. But who thought about the idea of pickles in the first place? Apparently, the idea of making pickles first came from the ancient civilisation of Mesopotamia, where archaeologists have found evidence of cucumbers being soaked in vinegar. This was done to preserve it, but the practice has spread all over the world today, that pickles mean so much more than just preserved vegetables.
In India, the idea of pickle has nothing to do with preservation, rather pickle is a side dish that adds flavour and taste to almost anything. In Punjab, parathas are served with pickle; in the south, pickle and curd rice is a household favourite, and in Andhra, it is a staple, eaten with everything. The flavour profile of pickles in each state is naturally different, suited to each cuisine's taste. Pickles are soaked in oil and salt for at least a month, mixed with spices and stored all year round. Mango season is often synonymous with pickle season as a majority of Indians love mango pickle. In the coastal cities, pickles are even made out of fish and prawns.
The Indian Achaar Image credit: Photo by Rahat Hossen on Unsplash
In other cultures, the pickling process has more to do with preservation. Cold countries, where temperatures drop to very low levels, pickle their vegetables in brine, vinegar, or salt. Sweden is famous for pickled herring, because fishing all year round is hard with all the snow and ice. The German Sauerkraut, originally composed of rice, cabbage, and wine, is now made using salt instead of wine. This gives it a sour flavour that is characteristic of the beloved German delicacy.
In Korea, kimchi is the national delicacy. It is a pickle that is made from pickled cabbages with a distinct mix of spices. Kimchi is made with various core ingredients, and is gaining popularity these days with the Korean Wave hitting the globe. It is a practice that represents the Korean winters, which are too harsh to grow anything. The Kimchi business is one of the largest in Korea, while the individual family recipes are also well-preserved as it is believed that each is unique in its own way.
The pickles made from dill and vinegar are most famous in America. It was introduced to the Americans by the Jewish immigrants. Dill pickles are best paired with sandwiches.
Keywords: Pickles, Culture, Brine, Vinegar, Preserves
It is impossible to detail the history of bookbinding without understanding the need for it. A very useful, and yet simple invention, spiral coils that hold books together and allow mobile access to the user came about just before WWII, but much before that, paper underwent a massive change in production technique.
Beginning in China, paper was made of bamboo sticks slit open and flattened. In Egypt, papyrus was made from the reeds that grew in the Nile. In India, long, rectangular strips of palm leaves were stitched together to form legible documents. When monasteries were established, scrolls came into being. Parchment paper, or animal hide, also known as vellum, were used to copy out texts periodically to preserve them. Prior to all this, clay tablets were used to record important events, and in some cases, rock edicts were made.
But all this changed with the invention of the printing press by Gutenberg. Paper became the medium by which inscriptions, announcements, and almost everything was made. Once paper became so accessible, printing began in full scale. Newspapers and the Bible were printed every day.
Metal coils were used before the world war Image credit: Photo by Dan Bucko on Unsplash
With wads of paper, something had to be done about keeping them together. Bookbinding began as a booming business. First, the pages were just sewn together. A special sewing machine was invented just for books. When this did not suit all book types, the process of punching and binding began. Holes were punched in books, and they were tied together.
Much later, an adhesive thermoplastic strip became available by which book pages were stuck together. They sold in this format for a long time. Ideas began to flow in for notebooks when people discovered that they could attach pieces of paper together. A machine was invented that drew lines. This made it easier for people who wrote a lot.
After a while, when people got used to having their books a certain way, The Spiral Binding Company opened in 1932, which changed the way bookbinding was done. Books could now be bound by coil and this was not only economical, but also convenient, because pages could easily be turned without breaking the bind. The original spiral bind coil was made of metal, but when supplies were rationed during WWII, they were made from plastic. This trend has remained to the present day, where spiral bound books are preferred to the other kinds of binding except in cases of publishing and official documentation.
Keywords: Spiral Binding, WWII, Paper, Books, Printing
By N. Lothungbeni Humtsoe
To keep the value and quality of what you offer, whether it's a romantic breakfast in bed or a royal wedding gift that will be remembered for years. The concept of gift-giving has taken on a number of shapes in today's society. Devina Singhania, the Founder of 'LE JAHAAN', a local home and decor accessories company, explains how the gifting paradigm has shifted.
Q: What do consumers expect from the gifting business and packaging designers these days?
A: Today's consumers are expecting more minimal sustainable products, designs and mediums. They are now more conscious about how their purchase affects the environment. Considering this shift in consumer buying, it's extremely important for companies to increase their commitments to responsible business practices and design products that are meant to be reused or recycled.
Today's consumers are expecting more minimal sustainable products, designs and mediums. | Photo by Superkitina on Unsplash
Q: The practice of self-gifting is being driven by millennials. What are your thoughts on the subject?
A: I absolutely agree with this. Millennials are so creative and expressive. They are more into personalized products with which they can tell the world something about themselves. We are often hired by millennials to monogram and personalize products for them. They truly believe it's the best way to stand out from the crowd and establish a signature style and we couldn't agree more.
We are often hired by millennials to monogram and personalize products for them. | Photo by freestocks on Unsplash
Q: What impact do colour trends have on gift designs and packaging?
A: 'Le Jahaan' has always been very influenced by colour and trends and we hope to continue this association with colour even while we break through to more sustainable products and collections.
'Le Jahaan' has always been very influenced by colour and trends | Photo by freestocks on Unsplash
Q: What has changed as a result of the pandemic in terms of how we commemorate special occasions and the gift-giving tradition?
A: It's smaller in quantity but more luxurious and thought through.
Q: What giving trends should one keep an eye on in 2022?
A: Consumers, including millennials and members of Generation Z, are especially concerned with sustainability. So, the trend is definitely to go green with eco-friendly.
Q: How does Le Jahaan keep its clients coming back?
A: Our products speak for themselves. We make small batches with exceptional quality with a personal touch.
(Article originally published on IANSlife) (IANS/ MBI)
Keywords: gifts, le jahaan, festive, millennials, sustainable, gen z, paradigm, gifting