Saturday January 19, 2019

Why migraines are more common among women

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Migraine

New York, Feb 8 : Females are more vulnerable to certain stress-related and allergic diseases such as migraines because of distinct differences found in mast cells, a type of white blood cell that is part of the immune system, says a study.

Mast cells are an important category of immune cells because they play a key role in stress-related health issues that are typically more common in women such as allergic disorders, auto-immune diseases, migraines and irritable bowel syndrome, or IBS.

“Over 8,000 differentially expressed genes were found in female mast cells compared to male mast cells,” said lead researcher Adam Moeser, Associate Professor at Michigan State University in the US.

“While male and female mast cells have the same sets of genes on their chromosomes, with the exception of the XY sex chromosomes, the way the genes act vary immensely between the sexes,” Moeser noted.

A further in-depth analysis of the genes within the RNA genome — a primary building block in all forms of life — revealed an increase in activity that is linked to the production and storage of inflammatory substances, according to the study published in the journal Biology of Sex Differences.

These substances can create a more aggressive response in the body and result in disease.

“This could explain why women, or men, are more or less vulnerable to certain types of diseases,” Moeser said.

With this new understanding of how different genes act, scientists could eventually start developing new sex-specific treatments that target these immune cells and stop the onset of disease, Moeser said. (IANS)

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Keep A Sleep Track During Pregnancy

Understanding the role of maternal sleep may help us identify interventions that would put us in a better position to advise women

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Pregnancy, Breast Cancer
Keep a check pregnancy check.

Sleeping more than nine hours per night during pregnancy may be associated with late stillbirth, suggests a new study.

This is because blood pressure reaches its lowest point during sleep which has been linked with foetal growth problems, preterm birth, and stillbirth.

The study, led by a team from the University of Michigan, explored how maternal sleep habits, including lengthy periods of sleep without waking more than once in the night, may be associated with foetal health independent of other risk factors.

Moreover, pregnant women often report waking up and getting up in the middle of the night.Very disruptive sleep has also been associated with poor pregnancy outcomes, including growth restriction and preterm growth.

The safety of domestic violence victims can also be potentially threatened by the discovery of a disposed of the test. Wikimedia Commons
Balanced sleep is important in pregnancy for a healthy baby.

“Our findings add to research indicating that maternal sleep plays a role in foetal well being. Studies aiming to reduce stillbirths should consider maternal sleep as this is a potentially modifiable risk factor,” said lead author Louise O’Brien, researcher at the varsity.

“Understanding the role of maternal sleep may help us identify interventions that would put us in a better position to advise women,” O’Brien added.

Also Read: Understanding the role of maternal sleep may help us identify interventions that would put us in a better position to advise women

For the study, reported in the journal Birth, the team involved 153 women who had experienced a late stillbirth (on or after 28 weeks of pregnancy) within the previous month and 480 women with an ongoing third-trimester pregnancy or who had recently delivered a live born baby during the same period.

Progress in reducing stillbirth deaths has been slow but stillbirth is an urgent global health issue that should be at the centre of more research programmes, the researchers noted. (IANS)