Saturday November 17, 2018

Wireless Device to Detect Heart Dysfunction in Cancer Survivors

Another alternative is cardiac magnetic resonance (CMR) imaging, which is expensive and is not widely accessible

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Cancer
Cancer Ribbon. Pixabay
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Scientists have designed a novel wireless device which may accurately detect heart dysfunction in children who have survived cancer.

Childhood cancer survivors are advised to undergo screening for the detection of heart dysfunction because of known anthracycline-induced cardiotoxicity.

However, screening with echocardiography — the standard of care for monitoring heart function — can be highly variable and limited.

Another alternative is cardiac magnetic resonance (CMR) imaging, which is expensive and is not widely accessible.

In the study, the team tested Vivio — a prototype handheld instrument which collects pulse waves and phonocardiogram data from the carotid artery. The results showed that the device was accurate and it displayed a low false-negative rate as compared to CMR imaging.

Cancer
Representational image. Pixabay

“This study is the first step in thinking about new paradigms of long-term monitoring and care delivery for cancer survivors who are at risk for severe and life-threatening health conditions,” said Saro Armenian, Director at City of Hope National Medical Centre in California.

The study, published in the journal Clinical Cancer Research, involved data from 191 patients exposed to anthracycline chemotherapy.

The data of the participants was collected using Vivio which then streamed wirelessly to a compatible device such as a smart phone or e-tablet.

This mobile health platform negates the need for result interpretation and allows for real-time monitoring of heart health, explained Armenian.

Also Read: Overweight in Middle Age Linked to Low Breast Cancer Risk

Using a specialised algorithm, Vivio measures the left ventricular ejection fraction (LVEF), which is commonly used to assess heart function and measures the percentage of blood ejected from the left ventricle of the heart, Armenian added.

However, the author said that Vivio is not currently intended to replace echocardiography or CMR imaging.

“One possible implementation of Vivio could be for preliminary screening,” Armenian explained. (IANS)

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Childhood Cancer Survivors More Likely to Experience Sleep Problems as Adults

Addressing disrupted sleep in these survivors may improve long-term psychological functioning

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Cancer
Cancer Ribbon. Pixabay

Childhood cancer survivors are more likely to experience sleep problems and daytime sleepiness as adults which may result in greater likelihood of persistent or worsened emotional distress, preliminary results of a study suggests.

The findings, presented during the SLEEP 2018 meeting in Baltimore, suggested that cancer survivors were more likely than siblings to report sleep problems as adults.

The researchers also found that survivors were 31 per cent more likely to report daytime sleepiness and 26 per cent more likely to have poor “sleep efficiency”.

“Our results indicate that for survivors of childhood cancer who reported sleep problems, there is a greater likelihood of worsening or persistent psychological distress,” said lead author Lauren Daniel, Assistant Professor at Rutgers University-Camden in New Jersey.

“Thus, addressing disrupted sleep in these survivors may improve long-term psychological functioning,” Daniel added.

Representational image.
Representational image. Pixabay

According to the researchers, sleep disorders are related to emotional and physical health in the general population, but research in survivors of childhood cancer is limited.

This study characterised sleep behaviours in adults who had survived childhood cancer and examined associations among sleep, cancer diagnoses, treatment exposures, and emotional functioning.

For the study, researchers examined 1,933 childhood cancer survivors. Participants had a mean age of 35 years and a mean time since diagnosis of 23.5 years. The study also involved 380 siblings with a mean age of 33 years.

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Both groups completed sleep quality, fatigue and sleepiness measures.

Emotional functioning was assessed about eight years before and two years after the sleep survey.

“Sleep is quite amenable to behavioural interventions. Efforts that improve sleep may improve both health and quality of life in long-term childhood cancer survivors,” said Daniel. (IANS)