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Women entrepreneurs must focus on scale and good team: Kiran Mazumdar

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Bengaluru: Kiran Mazumdar, Biocon Chairperson on Thursday said women entrepreneurs must focus on scale and building a good team.

“As women, we must focus on building scale. If you don’t build scale, I really believe you will be at a disadvantage. You cannot then build a credible business story,” said Shaw at panel discussion ‘Promoting Women Entrepreneurship’ at Invest Karnataka 2016 Global Investors Meet (GIM).

According to Shaw, scaling process is a daunting task without creating a good team.

“A good team with critical competencies about business modeling, about finance and about marketing is a very important contributor to scaling and success,” she said at the discussion attended by women entrepreneurs from across Karnataka.

Shaw considers her bio-technology company Biocon as the first startup to emerge from Bengaluru and narrated the difficulties she faced while sharing it.

“In 1978, the bankers did not have faith in me that I, being a woman, am capable of setting up a business. Loans for women entrepreneurs were classified under the handicapped and backward classes category,” she revealed.

She thanked Karnataka State Industrial Investment and Development Corporation (KSIIDC) and Karnataka State Finance Corporation (KSFC) for coming to her aid and approving the loan.

The panel discussion also hosted a sister city initiative agreement signing between Bengaluru and San Francisco. Additional Chief Secretary Ratna Prabha and Sister City Initiatives co-chair Nandini Tandon exchanged the agreement.

Earlier, Women Entrepreneurs Guidance Cell (Mahila Udyamavani Cell) was launched to give a shot in the arm for women entrepreneurs.(IANS)

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Males Have Higher Risk of Suffering from Cancer: Study

Researchers explain why cancer risk is higher in males

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Cancer
DNA differences between men and women may explain why cancer risk is higher in males. Pixabay

DNA differences between men and women may explain why cancer risk is higher in males, according to a new study.

In findings published in the Journal of the National Cancer Institute, researchers have reported that loss of function in certain genes of the sex-determining Y chromosome, which is present only in men, may cause them to have an elevated risk for cancer.

Using data from 9,000 individuals, the researchers studied Y-chromosome gene function in patients with various types of cancer. The findings showed that cancer risk increases with loss of function of six key Y-chromosome genes in various types of cells.

“Recent studies have shown that complete loss of the Y chromosome, which is essential to foetal sex differentiation, occurs, with aging, in the cells of some men,” said study author Juan Ramon Gonzalez from Barcelona Institute for Global Health in Spain.

Cancer DNA
Suppression of the Y chromosome can occur as a result of loss of function in the chromosome. Pixabay

“Although the loss of the Y chromosome has previously been associated with higher incidence of cancer, the causes of this association are poorly understood,” Gonzalez added.

These six Y-chromosome genes are involved in cell-cycle regulation, the failure of which can lead to tumour development.

According to the study, understanding the biological differences between men and women in cancer is crucial for the development of personalised lines of treatment and prevention.

“Men are not only at higher risk of cancer than women, they also face a worse prognosis. In fact, these differences partially account for the lower life expectancy of men,” Gonzalez added.

According to the researchers, although men may be more exposed to carcinogens due to the type of work they do and at higher risk because they are less likely to consult a doctor, the study has shown that there are also biological factors that increase cancer risk among men.

“In fact, it seems that one of these factors can be found in the Y chromosome, the very essence of maleness,” said study lead author Alejandro Caceres.

Also Read- Know About the Health Benefits of Green Tea

Suppression of the Y chromosome can occur as a result of loss of function in the chromosome, which would explain previous findings, or as a result of other mechanisms mediated by the chemical (epigenetic) inactivation of the same regions, the research said.

“Certain environmental exposures, for example to tobacco or other harmful substances, could affect chromosome function and lead to epigenetic modifications,” Gonzalez said. (IANS)