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Females are better able to keep their blood pressure down by increasing levels of a T cell. Pixabay

Now you know why your wife keeps her blood pressure down even when you keep on sulking during a quarrel at home. According to an interesting research, females have an innate ability to increase levels of anti-inflammatory T cells to keep their blood pressure down.

Called Tregs, the cells are known to help protect us from an excessive immune response, and are naturally associated with lower blood pressures and less organ damage.


Females, at least before menopause, tend to have lower blood pressures than males.

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“We think, based on studies in this and other models, that the ability of the female to maintain or upregulate those T regulatory cells is critical to their ability to maintain a lower pressure,” said Dr. Jennifer C. Sullivan, professor in the Department of Physiology at the Medical College of Georgia at Augusta University.


The T cell’s levels are known to increase to help maintain a healthy pregnancy. Pixabay

In the face of a multipronged front to drive blood pressure up, including a high-salt diet, females are better able to keep their pressure down by increasing levels of a T cell that selectively dials back inflammation.

The T cell’s levels are known to increase to help maintain a healthy pregnancy, for example, so the immune system does not attack the fetus, which has DNA from both parents.

“This is just a different challenge, but we are using those same protective pathways to do something else good for us,” said Sullivan.

Sullivan’s work, published in the journal Hypertension, supports the hypothesis that females rely heavily on Tregs for blood pressure control and this mechanism accounts for at least one of the sex differences in that control.

“It’s a compensatory response to an increase in blood pressure to help the overall cardiovascular impact,” Sullivan said of this innate ability that could provide a promising new hypertension treatment strategy, particularly for women.

Sullivan suspects males and females likely make similar numbers of Tregs — they have found similar numbers in the spleen, for example — but differences may be in the recruitment and proliferation to organs key to blood pressure control like the kidneys, one reason she wanted to look specifically at Treg levels there.

Both sexes actually experienced increases in pro-inflammatory T cells, which contribute to infection fighting.

In rats, blood pressure increased significantly in both sexes by day two, but by the end of 21 days of treatment, male blood pressures were significantly higher.

And, females experienced significantly more of the blood pressure-mitigating Tregs along with their lower pressures, the scientists report.

The fact that decreasing Tregs in males did not affect blood pressure may indicate that male blood pressure is not as dependent on this mechanism during normal conditions.

However the clear impact in females supports the hypothesis that females are “highly dependent” on Tregs to maintain their pressure.

The hormone DOCA, or deoxycorticosterone acetate, prompts the kidneys to hold onto both more sodium and water, so there is a higher fluid volume in the blood vessels, which drives up blood pressure.


Decreasing Tregs in males did not affect blood pressure. Pixabay

Also Read: ISRO Gets Indian Patent for Liquid Cooling and Heating Garment, Suitable for Space Applications

Then, as with some humans, a high-salt diet magnifies the problem and so does the removal of a single kidney.

This DOCA-salt model is a commonly used hypertension model, which provides scientists a good window for when hypertension sets in.

“If we can better understand how and why females are increasing their Tregs that could lead to therapies, potentially for both sexes, to also avoid or treat high-inflammation conditions like autoimmune and cardiovascular disease,” Sullivan noted. (IANS)


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Photo by Pixabay

Upcoming medical colleges in Uttar Pradesh will be named after saints and sages

The new medical colleges being opened in Uttar Pradesh will be named after saints and sages.

The state government has issued an order naming four district hospitals that are being converted into medical colleges.

These district hospitals are in Bijnor, Fatehpur, Chandauli, and Siddharth Nagar.

The Bijnor medical college has been named after Mahatma Vidur, a philosopher during the Mahabharata era and uncle of the Pandavas and Kauravas.

The Chandauli medical college has been named after Baba Keenaram, said to be the founder of the Aghori sect.

The Siddharth Nagar district hospital will be called Madhav Prasad Tripathi Medical College after the BJP politician from the region. Tripathi, popularly known as Madhav Babu, was also the first Uttar Pradesh BJP chief. He was elected MP from Domariyaganj in 1977, besides being two times Jan Sangh MLA and also a member of the UP legislative council.

The Fatehpur hospital has been named Amar Shaheed Jodha Singh Ataiya Thakur Dariyawn Singh Medical College, after the freedom fighter of 1857.

It is said that he was among the first to use Guerrilla warfare against the British, as taught by freedom fighter Tatya Tope.

Meanwhile, according to official sources, the medical college in Deoria will be named after Maharishi Devraha Baba and the medical college of Ghazipur in the name of Maharishi Vishwamitra.

The medical college of Mirzapur will be in the name of Maa Vindhyavasini, the medical college of Pratapgarh in the name of Dr. Sonelal Patel and the medical college of Etah will be named after Veerangana Avantibai Lodhi. (IANS/JB)

Keywords: Medical Colleges, Uttar Pradesh, Yogi Adityanath, India, Politics


Photo by Wikimedia Commons

Photo of Indian cricket team on the ground

Former Pakistan captain Inzamam-ul-Haq has picked India as the favourite to win the ongoing ICC Men's T20 World Cup in Oman and United Arab Emirates (UAE).

Inzamam feels that the Virat Kohli-led India have a greater chance of winning the trophy as the conditions in the Gulf nations are similar to the subcontinent, which makes India the most dangerous side in the event, according to Inzamam.

"In any tournament, it cannot be said for certain that a particular team will win' It's all about how much chance do they have of winning it. In my opinion, India have a greater chance than any other team of winning this tournament, especially in conditions like these. They have experienced T20 players as well," said Inzamam on his YouTube channel.

He said more than the Indian batters, the bowlers have a lot of experience of playing in the conditions. The Indian Premier League (IPL) was played recently in UAE and most of the Indian bowlers did well in that leg.

Inzy heaped praises on the Men in Blue for the confident manner in which they chased the target against Australia on a challenging track without needing Kohli's batting prowess.

"India played their warm-up fixture against Australia rather comfortably. On subcontinent pitches like these, India are the most dangerous T20 side in the world. Even today, if we see the 155 runs they chased down, they did not even need Virat Kohli to do so," he added.

Though he did not pick any favourite, Inzamam termed the India-Pakistan clash in the Super 12 on October 24 as the 'final before the final' and said the team winning it will go into the remaining matches high on morale,

"The match between India and Pakistan in the Super 12s is the final before the final. No match will be hyped as much as this one. Even in the 2017 Champions Trophy, India and Pakistan started and finished the tournament by facing each other, and both the matches felt like finals. The team winning that match will have their morale boosted and will also have 50 percent of pressure released from them," Inzamam added. (IANS/JB)

Keywords: India, Pakistan, Sports, ICC T20 World Cup, UAE.


Photo by Diana Akhmetianova on Unsplash

Skin problems like itchiness, dryness and flakiness can occur anytime if you're not moisturising your body enough.

Skin problems like itchiness, dryness and flakiness can occur anytime if you're not moisturising your body enough. It is commonly observed that while many people take their skincare routine seriously, a majority of them neglect to moisturise the body. It is important to keep in mind that timing matters a lot when it comes to applying moisturisers. Therefore, knowing the appropriate time to apply body lotion is essential.

Take a look at the ideal times to moisturise your body shared by Kimi Jain, Head of Retail, KIMRICA.

Morning
Moisturising the body in the morning sets your skin up to face countless irritants and environmental factors during the day. The skin is constantly exposed to harsh chemicals and pollutants when you're outside which is why using a protective and soothing moisturiser while going out is necessary. Kimirica's Five Elements Body Lotion comes with natural Aloe Vera extracts that act as a rich source of antioxidants and vitamins that helps protect your skin and provide a deep nourishing effect.

man in white crew neck t-shirt Moisturising the body in the morning sets your skin up to face countless irritants and environmental factors during the day. | Photo by The Creative Exchange on Unsplash

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