Wednesday August 21, 2019

Women Having Slim Hips Could Be At Risk of Developing Diabetes, Heart Attacks

Findings, published in the JAMA medical journal, showed that both of the genetic variants identified were associated with higher risk of Type-2 diabetes and heart attacks

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Diabetes

While putting on weight is dangerous for health, women who have slim hips could be at risk of diabetes and heart attacks, finds a new research.

The study showed that putting on weight around the hips is actually safer than accumulation around the belly or around other major organs such as the liver or pancreas.

The reason could be because some women are genetically less able to store fat at the hips, which puts them at risk of Type-2 diabetes and heart disease.

Also, putting on fat is more likely to circulate in the blood.

“This means that individuals with this genetic make-up preferentially store their excess fat in the liver, muscles or pancreas, or in their blood in the form of circulating fats and sugar, any of which can lead to a higher disease risk,” said Luca Lotta, lead researcher from the University of Cambridge.

Diabetes
Representational image. Pixabay

“It may seem counter-intuitive to think that some people with less fat around their hips are at higher risk of diabetes or heart disease,” said Lotta.

For the study, the researchers studied the genetic profiles of more than 600,000 women.

They identified two specific groups of genetic variants — one that lowers fat around the hips and another increasing fat around the waist and belly.

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Findings, published in the JAMA medical journal, showed that both of the genetic variants identified were associated with higher risk of Type-2 diabetes and heart attacks.

Genetics which specifically change fat distribution by lowering fat storage around the hips increase risk of disease independent of, and in addition to, mechanisms that affect abdominal fat storage, the study noted. (IANS)

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Women with Obstructive Sleep Apnea (OSA) at Elevated Risk of Getting Cancer

It's reasonable to assume that sleep apnea is a risk factor for cancer or that both conditions have common risk factors, such as overweight

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Women, OSA, Cancer
The study, published in the European Respiratory Journal, is based on analyses of registry data, collected in the European database ESADA, on a total of some 20,000 adult patients with obstructive sleep apnea (OSA). Pixabay

Women with obstructive sleep apnea (OSA) appear to be at an elevated risk of getting cancer than men with the condition, warn researchers.

The study, published in the European Respiratory Journal, is based on analyses of registry data, collected in the European database ESADA, on a total of some 20,000 adult patients with obstructive sleep apnea (OSA). About 2 per cent of them also had a cancer diagnosis.

“It’s reasonable to assume that sleep apnea is a risk factor for cancer or that both conditions have common risk factors, such as overweight. On the other hand, it is less likely that cancer leads to sleep apnea,” said Ludger Grote, Professor at the University of Gothenburg in Sweden.

According to the researchers, advanced age was associated with elevated cancer risk, but adjusting the data for age, gender, body mass index (BMI), smoking and alcohol consumption nevertheless showed a possible link between intermittent hypoxia at night and higher cancer prevalence.

Women, OSA, Cancer
Women with obstructive sleep apnea (OSA) appear to be at an elevated risk of getting cancer than men with the condition, warn researchers. Pixabay

The connection applied mainly to women and was weaker in men.

“Our results indicate a cancer risk that’s elevated two- to three-fold among women with pronounced sleep apnea,” Grote said.

The condition of sleep apnea is well known to the general public and associated with snoring, daytime fatigue, and elevated risk of cardiovascular disease, especially in men, said the study.

This research paves the way for a new view — that sleep apnea may possibly be connected with increased cancer risk, especially in women.

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“Above all, the focus has been on the connection with one form of cancer: malignant melanoma. Cancer of the breast or womb may now become a new area. There may be a combined effect of female sex hormones and stress activation, induced by nocturnal hypoxia in sleep apnea, that can trigger cancer development or a weakening of the body’s immune system,” Grote concluded. (IANS)