Friday March 22, 2019

World No Tobacco Day special: Smoking Hukkah more dangerous than using cigarettes

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New Delhi: Seventeen-year-old Harsh Mahajan could not understand the pain in his chest while breathing or why the colour of his sputum was changing. The class eight dropout, who got addicted to the hukkah (Indian water pipe) smoking at an early age, kept ignoring his health complications till the day his parents saw him coughing blood.

After several tests were conducted at a hospital, both of Mahajan’s lungs were found to be filled with tar caused due to the tobacco smoke inhaled through the hukkah. Though medical experts started treating the teenager, he succumbed to lung cancer – serving as a warning for his friends who were similarly addicted.

Recent studies have concluded that in India the percentage of students who initiate hukkah smoking before 10 years of age has increased from 26 per cent to 45 per cent in the last one decade.

Health experts said that at least 40 percent of school-going students get into smoking the hukkah, to quench their desire for smoking cigarettes, thinking that the lower of tobacco content in hukkahs won’t harm their health.

“The existing myths compel youngsters to get into the practice of smoking hukkahs. A lot of people are still under the impression that the hukkah is an alternate to cigarettes, with less harm to health, but they are not able to understand that a typical one-hour-long hookah smoking session involves 200 puffs, while an average cigarette requires 20 puffs. This makes the hukkah more dangerous for the human body,” Kedar Toraskar, Chest Physician at Mumbai-based Wockhardt Hospital, told IANS.

He said that the volume of smoke inhaled during a typical hookah session was about 90,000 milliliters, compared to 500 to 600 milliliters of smoke inhaled by smoking a cigarette.

Emphasising that hukkah smoking was emerging as one of the prime reason behind the rising lung-related disease among youngsters, Toraskar said that the harmful toxins in hukkahs also caused respiratory illness, low birth weight and periodontal diseases among many.

He revealed that babies born to women who smoked a hukkah every day were likely to be 3.5 ounces less in weight than the babies delivered by a non-smokers. Explaining how somking a hukkah causes damage to the human body, Toraskar said: “The smoke produced by the charcoal burning in the hukkah contains high levels of carbon monoxide, metals and cancer-causing chemicals which does the same damage that cigarette or a bidi does to a human body.”

The World Health Organisation (WHO) says tobacco causes over five million deaths world wide which is likely to increase to 8.4 million if the situation is not brought under control. Tapaswini P. Sharma, senior consultant of surgery at Delhi-based B.L.K. Hospital said: “A lot of people are under the impression that the water used in the hukkah reduces the harmful affect of tobacco and causes no harm to the lungs, however this is not true as the toxins remains insoluble.”

“In fact, hookah use can also impair cardiac functions, and lead to cancers of the esophagus, mouth, lung, stomach, and decreased fertility. All the harmful effects associated with cigarettes are very much prevalent with the hookas too,” Sharma told IANS. Sudhir Khandelwal, head of the psychiatric department at AIIMS, said every form of tobacco consumption such as hukkah, inhaling and the pan causes the same damage that chewing tobacco does.

“Though a person starts with hukkah occasionally, but with time they become addicted to it,” Khandelwal told IANS, adding that the youth consuming tobacco in any form were more likely to get into active cigarette smoking. “In all, 50 percent of the cancers in India are directly or indirectly related to tobacco consumption,” he said.

On the other health damage caused by hukkahs, Rajeev Dewan, senior consultant in Internal Medicine at Delhi-based Saroj Super Specialty Hospital, said that tobacco juices from hukkahs affect the mouth and increases the risk of developing oral cancers. “As a substitute, there are also e-hukkahs available which are considered to be nicotine free. But these are all false myths as they do contain some amount of nicotine and cancerous elements which are enough to cause the same damage any tobacco related product does to a human body,” Dewan said. (IANS)

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Researchers Discover Balance of Two Enzymes That May Help Treat Pancreatic Cancer

While still in the earliest stages, Newton hoped this information might one day aid pancreatic diagnostics and treatment

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Cancer
Cancer Ribbon. Pixabay

A new research has set the stage for clinicians to potentially use levels of a pancreatic cancer patient’s PHLPP1 and PKC enzymes as a prognostic and for researchers to develop new therapeutic drugs that change the balance of the two enzymes as a means to treat the disease.

The study, published on Wednesday in Molecular Cell, was led by Alexandra Newton, professor in the Department of Pharmacology at the University of California, San Diego, School of Medicine, and Timothy Baffi, a graduate student in her lab, Xinhua news agency reported.

The new study built on the team’s work in 2015 that found the enzyme PKC, which was believed in previous studies to promote tumour growth, actually suppressed it.

The latest study took the investigation a step further by uncovering how cells regulate PKC activity and discovered that any time an over-active PKC is inadvertently produced, the PHLPP1 “proofreader” tags it for destruction.

Cancer patient
Cancer patient.

“That means the amount of PHLPP1 in your cells determines your amount of PKC,” Newton said. “And it turns out those enzyme levels are especially important in pancreatic cancer.”

The team observed 105 pancreatic cancer tumours to analyze the enzyme levels in each one. About 50 per cent of patients with low PHLPP1/high PKC lived longer than five-and-a-half years.

Also Read- A Brain Circuit Can Help Reverse Craving for Liquor, Says Study

While still in the earliest stages, Newton hoped this information might one day aid pancreatic diagnostics and treatment.

Pancreatic cancer is caused by the abnormal and uncontrolled growth of cells in the pancreas, a large gland in the digestive system. It typically doesn’t show symptoms in the early stages. Sufferers tend to develop signs, such as back pain and jaundice, when it has spread to other organs. (IANS)