Never miss a story

Get subscribed to our newsletter


×
Spreading focal lesions are generally larger and spread outwards into areas of healthy cells, while isolated focal lesions, have a capsule around them that keeps the diseased cells separate from healthy cells. Pixabay

Babies born with abnormally high levels of insulin are at the risk of suffering permanent brain damage and life-long disability, finds a study that showed it’s possible to predict when and how the condition may affect the child in the long-term.

The generally rare condition, called congenital hyperinsulinism, can also be as common as cystic fibrosis in children born into communities where cousins marry.


So far, scientists understood that there were two main subtypes of the disease known as diffuse — affects the entire pancreas — and focal — affects just one area of the organ.


In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated. Pixabay

In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated.

The new study, led by a team from the University of Manchester in the UK, showed that focal CHI can be further categorised into two types — spreading focal lesions and isolated focal lesions.

Spreading focal lesions are generally larger and spread outwards into areas of healthy cells, while isolated focal lesions, have a capsule around them that keeps the diseased cells separate from healthy cells.

For the study, published in the Frontiers in Endocrinology journal, the team investigated the cases of 25 infants with focal CHI to see how the two types of lesions influenced their long-term outcomes.

They found babies with spreading focal lesions suffered more severely from the disease and were diagnosed earlier. These infants were more likely to suffer brain damage, which permanently affected their development, learning and behaviour.


The generally rare condition, called congenital hyperinsulinism, can also be as common as cystic fibrosis in children born into communities where cousins marry. Pixabay

In contrast, in infants with isolated lesions, the disease was diagnosed later and surgery to remove the lesion was less complicated.

These data help to explain why newborn babies diagnosed with the same disease may go on to have very different outcomes and could influence the way clinicians choose to manage each new case of CHI.

Also Read:‘Model Chinese’ Parents Who Spent Their Careers As Loyal Civil Servants, Get Free of Uyghur Exile After Daughter’s Interview

“One of the problems facing clinicians is that it’s really difficult to predict which babies will have problems after surgical treatment,” said Karen Cosgrove, from the varsity.

“Our data gives some important clues that will help clinicians to know how much extra care each baby is likely to need,” Cosgrove said. (IANS)


Popular

Unsplash

When you're pregnant, the immune system is seeing the placenta for the first time in decades.

The US researchers have discovered a class of immune cells that plays a role in miscarriage, which affects about a quarter of pregnancies.

Researchers at the University of California-San Francisco found that the recently discovered subset of cells known as extrathymic Aire-expressing cells in the immune system may prevent the mother's immune system from attacking the placenta and fetus.

The researchers showed that pregnant mice who did not have this subset of cells were twice as likely to miscarry, and in many of these pregnancies fetal growth was severely restricted.

ALSO READ: Can You Drink Coffee While You're Pregnant?

"When you're pregnant, the immune system is seeing the placenta for the first time in decades -- not since the mother made a placenta when she herself was a fetus," said Eva Gillis-Buck, from UCSF.

"Our research suggests that this subset of immune cells is carrying out a sort of 'secondary education' -- sometimes many years after the better-known population of the educator cells have carried out the primary education in the thymus -- teaching T cells not to attack the fetus, the placenta and other tissues involved in pregnancy," she added. The findings are published in the journal Science Immunology.

Keep Reading Show less
Unsplash

It's not surprising that over half of those surveyed feel more comfortable using emojis than talking on the phone or in person.

The tiny emojis being shared on billions of devices worldwide can play a major role in digital communication, with most people saying that emoji compels them to feel more empathy towards others, according to an Adobe report.

Adobe's global emoji study found that emoji even helps people overcome language barriers and form connections that would otherwise be difficult to do.

"We were surprised and delighted by the discoveries made in the survey, most notably how enthusiastic respondents were for emoji as a means to express themselves," the company said in a statement.

ALSO READ: Emoji- A Choice for Interracial Couple

Emojis sometimes get criticized for being overly saccharine, but this sweetness is key when it comes to diffusing some of the heaviness of online communication.

"Many of the emoji are focused on positive emotions, so it's easy to insert them into our conversations and lighten the mood," the Adobe study said.

Keep Reading Show less
Wikimedia Commons

Jeff Bezos at the ENCORE awards.

Following the grand Richard Branson show where he carried Andhra Pradesh-born Sirisha Bandla and fellow space travelers on his shoulders after successfully flying to the edge of space, it is time for Amazon Founder Jeff Bezos to applaud Sanjal Gavande, one of the key engineers who designed the New Shephard rocket set to take Bezos and the crew to space on July 20.

Billionaire Bezos is set to fly to the edge of space aboard what is touted as the world's first unpiloted suborbital flight. Born in Kalyan, Maharashtra, Gavande is a systems engineer at Blue Origin who always dreamt of designing aerospace rockets.

ALSO READ: Jeff Bezos Used To Review Products On Amazon

After completing Bachelor's in mechanical engineering from the University of Mumbai, she flew to the US in 2011 to pursue a Master's in mechanical engineering from the Michigan Technological University. She also applied for an engineering job at the US space agency NASA but finally landed her dream job at Blue Origin

Keep reading... Show less