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London: A 10-km wide asteroid that wiped out dinosaurs when it crashed into earth over 65 million years ago contains a rare metal — iridium — that could be used in the effective treatment of cancer, researchers have found.
Scientists from the UK and China have demonstrated that iridium — a rare metal delivered to Earth by the asteroid — can be used to kill cancer without harming healthy cells.
Laser-based techniques are emerging as viable treatments for cancer, targeting tumours far more precisely than the shotgun blast of radiation and chemotherapy. Researchers from the University of Warwick in the UK and Sun Yat-Sen University in China have found that laser light can turn iridium into an effective cancer killer, the newatlas.com reported.
The team created a compound of iridium and organic materials, and then introduced it into a lung cancer tumour grown in the lab. When red laser light is shone onto it through the skin, the compound is activated, converting the oxygen in the tumour into singlet oxygen, a poisonous form of the element that effectively kills the cancer cells from the inside. With cancer becoming resistant to certain treatments, it’s crucial to find new methods such as this.
Further study found that the compound was effective as it managed to penetrate every layer of the tumour.
The team used ultra-high resolution mass spectrometry to highlight which proteins in the cancer cells were being targeted. They found that the compound had damaged proteins that manage heat shock stress and glucose metabolism, which are known to be crucial molecules for cancer’s survival.
When the researchers tested the iridium compound on a clump of non-cancerous tissue they found it had no effect, meaning it seems to be a highly targeted treatment that doesn’t attack healthy cells. The research was published in the journal Angewandte Chemie.
Iridium is relatively rare on Earth naturally, but scientists have found a spike in the Chicxulub crater, an impact crater buried underneath the YucatÃ¡n Peninsula in Mexico, which is often associated with the asteroid impact that wiped out the dinosaurs.
“The precious metal platinum is already used in more than 50 per cent of cancer chemotherapies,” says Peter Sadler, lead author of the study. “The potential of other precious metals such as iridium to provide new targeted drugs that attack cancer cells in completely new ways and combat resistance, and which can be used safely with the minimum of side-effects, is now being explored. It’s certainly now time to try to make good medical use of the iridium delivered to us by an asteroid 66 million years ago!” — IANS
Every year, December 3 is observed as International Day of Persons with Disabilities. This day is observed with a motive to promote the rights and well-being of persons with disabilities in all spheres of society.
It must be noted that almost one billion people out of the total population of 7 billion live with some form of disability. And, more than 100 million disabled persons are kids.
It would be right to say that persons with disabilities have been affected “disproportionately" by the health, social, and economic consequences of the global issues.
Therefore, the day is observed to raise participation of the disabled in the sustainable development of the world.
It was decided in the year 1992 by United Nations General Assembly (UNGA) resolution 47/3, that this day must be observed annually. The primary aim of was to increase awareness of the issues faced by persons with disabilities in almost every aspect of political, social, economic, and cultural life.
Moreover, after working in the field of disability, the Convention on the Rights of Persons with Disabilities (CRPD) was adopted in the year 2006. The CRDP advanced the rights and well-being of persons with disabilities in the implementation of the 2030 Agenda for Sustainable Development and other international development frameworks. The main purpose behind this was to increase participation of disabled people in society, end discrimination towards them, and create equal opportunities for them.
Every year, a theme is selected, and so this year’s theme is, “Leadership and participation of persons with disabilities toward an inclusive, accessible and sustainable post-COVID-19 world."
This International Day of Persons with Disabilities, let us pledge to make a friendly and sustainable environment for the disabled!
(Keywords: Health, Disability, International Day of Persons with Disabilities, Sustainable Development, UNGA, World)
Groove to the latest wedding song, Say Yes To The Dress India, with the king of Music, Badshah, who for the first time, will be donning five never seen before avatars including that of an event manager, pandit, chef, rapper and a fashion designer in the music video displaying an Indian wedding. The song will be available on all leading audio streaming services.
Joining him as the female lead singer is Payal Dev and the track is composed by Aditya Dev, produced by The Content Team. Highly celebrated Punit J Pathak has choreographed it. The video showcase real-time brides but also successfully brings out the show's core theme of fun, celebration and giving each bride the attention they deserve. While the show is visually mesmerizing, the rapper's newest wedding track is sure to get one swaying, making its way to the top of your playlist!
It's always a fun time working with Badshah and this song is nothing less than magic to the ears. Since we thoroughly enjoy this track ourselves, I am sure the audiences too will give it just the amount of love it deserves", said Singer Payal Dev. Neeraj Sharma, Founder and Principal producer of The Content Team said, "We at 'TCT' believe in coming up with creative solutions that bring audiences closer to the content. Buoyed by the recent successes of some of the prestigious singing reality shows in India, we have a fair understanding of what consumers are looking forward to in the music industry. We are thrilled to bring to you the biggest shaadi blockbuster of the year." (IANS/ MBI)
(Keywords: Punit J Pathak, Aditya Dev, Payal Dev, Badshah, king of Music, Yes To The Dress India, wedding song)
Rapper Cardi B has been named Playboy's first-ever creative director in residence. The 'WAP' hitmaker took to social media to share the news, which will see her become the very first person to be creative director in residence of the iconic brand, reports femalefirst.co.uk. Sharing the news on Instagram, she said: "Introducing the FIRST EVER Creative Director In Residence at the legendary @playboy, it's ME!!! Joining the @playboy family is a dream and I know y'all are going to love what we put together. "I'm startin this party right as the Founding Creative Director and a founding member of Centerfold the new creator-led platform from Playboy coming soon!! We're going to have soooooo much fun."
According to a press release obtained by People magazine, Cardi's role will involve providing "artistic direction" across the Playboy brand. | IANS
According to a press release obtained by People magazine, Cardi's role will involve providing "artistic direction" across the Playboy brand. The release stated: "Cardi will provide artistic direction across co-branded fashion and sexual wellness merchandise collections, digital editorial, experiential activations and more. "In addition, Cardi B will serve as the Founding Creative Director and a founding member of Playboy's upcoming creator-led platform, Centerfold."
According to People, Centerfold is expected to launch this month and will be Playboy's social content platform that will offer creators tools to directly interact with fans. In the release, 29-year-old Cardi said: "It is a dream come true to officially join the Playboy family. I can't believe this is real. For as long as I can remember, I've felt connected to Playboy. It's truly the original platform for uncensored creativity and I'm inspired by its incredible legacy of fighting for personal freedoms. I have so many ideas already - I can't wait! "I'm also excited to launch our new creator-led platform, Centerfold. Creators today deserve to express themselves freely and unfiltered. They deserve to feel safe in their creativity and sexuality. And they deserve to own their future. "This is what Centerfold is all about. For all those creators out there doing bold, revolutionary, truly culture-shifting things, come join me." (IANS/ MBI)
(Keywords: Instagram, WAP, residence, creative director, Playboy, Cardi B, Rapper)