Never miss a story

Get subscribed to our newsletter


×
Connection between Brain and Immune System. Image Source: www.deccanchronicle.com
  • The researchers developed and employed a novel systems-biology approach to investigate the complex dialogue between immune signalling and brain function in health and disease
  • The researchers predicted an unexpected role for interferon gamma (IFN-?), an important substance secreted by immune cells, in promoting social brain functions
  • Restoring of IFN-?-signalling in the brain normalised brain activity and social behaviour

A new research suggests that neurological diseases such as autism-spectrum disorders and schizophrenia can be caused by malfunctioning of immune system


Autism: A Neurological Disease. Image Source: www.americanhealthreview.com


“Our findings contribute to a deeper understanding of social dysfunction in neurological disorders, such as autism and schizophrenia, and may open new avenues for therapeutic approaches,” said Vladimir Litvak, Assistant Professor at the University of Massachusetts Medical School in the US.

The study was published in the journal Nature.

Follow NewsGram on Twitter: @newsgram1

The researchers developed and employed a novel systems-biology approach to investigate the complex dialogue between immune signalling and brain function in health and disease.


Immune defence. Image Source: www.huffingtonpost.ca

Using this approach, the scientists found that immune system signalling can directly affect, and even change, social behaviour in mice and other model animals.

The researchers predicated an unexpected role for interferon gamma (IFN-?), an important substance secreted by immune cells, in promoting social brain functions.

In the course of the research, they found that blocking IFN-? in mice made mouse brains become hyperactive and caused atypical social behaviour.


Tridimensional structure of human interferon gamma. Image Source: en.wikipedia.org

Restoring of IFN-?-signalling in the brain normalised brain activity and social behaviour.

Follow NewsGram on Facebook: NewsGram.com

“The brain and the adaptive immune system were thought to be isolated from each other, and any immune activity in the brain was perceived as a sign of pathology,” said Jonathan Kipnis from the University of Virginia.

“And now, not only are we showing that they are closely interacting, but some of our behaviour traits might have evolved because of our immune response to pathogens,” Kipnis explained. (IANS)

ALSO READ:


Popular

Photo by febri sym on Unsplash

Achieving soft, beautiful and happy skin is a dream for most of us or at least a long-pending item on our wish list.

Achieving soft, beautiful and happy skin is a dream for most of us or at least a long-pending item on our wish list. While there are lot of suggestions, a laundry list of do's and don'ts to follow, there are some basics that don't change. We have to understand that happy skin is a holistic process that requires one to work on building healthy habits combined with good skincare.

Here's a ready reckoner by ITC Fiama of tried and tested skincare habits that will serve as a reminder that skincare doesn't need to be complicated, it just needs to be consistent.


* Cleanse & Moisturise -- The first and the simplest step towards healthy skin is regular cleansing and moisturising, it is advisable to use a moisturizing body soap that ensures your skin gets the right nutrients and remains supple and nourished. A great product suited to this requirement is Fiama Gel Bathing Bar, which is enriched with nature's goodness. Fiama's bathing bars come in 5 variants and they help moisturize the skin making it appear soft, happy and bouncy.

Keep Reading Show less
Photo by Pixabay

It is true that street performances has been existing in India since ancient times. But, it was Philip Astley who brought the concept of circus in India in the 1880s. Interestingly, Astley is known as the father of modern circus.

Birth of the Great Indian Circus

Keep Reading Show less
Unsplash

API security testing is a process that checks API functions for security vulnerabilities.

By- Naman Rastogi

The first thing to understand about API security testing is that it is not a one-size-fits-all process. Testers must take into account the scope of the project, as well as the specific needs of developers and end-users. This article will provide you with some basic guidelines for an API security testing program. It will also outline some API security tests that you should consider including in your API testing process.

Keep reading... Show less