Monday April 22, 2019

High BP Medicine May Help Treat Migraine

Migraines are thought to affect a staggering one billion people worldwide

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High BP Medicine May Help Treat Migraine
High BP Medicine May Help Treat Migraine. Pixabay

A medication originally used to treat high blood pressure may help you from migraine pain attacks.
Candesartan – a drug used to treat high blood pressure – is just as effective as the commonly prescribed propranolol for migraine sufferers, according to a study.

The researchers also found that candesartan may work for patients who get no relief from propranolol.

“This gives doctors more possibilities and we can help more people,” said professor Lars Jacob Stovner, from Norwegian University of Science and Technology (NTNU).

“Candesartan is already in use by several doctors as a migraine preventive medicine but our follow-up study provides the proof that the drug actually works as a treatment,” said the researchers.

Representational image.
Representational image. Pixabay

The NTNU study was a triple blind test, which means that neither patients nor doctors nor those who analysed the results knew whether the patients had been given placebo or real medicine, Stovner said.

Researchers tested both candesartan and propranolol in 72 patients.

These patients were normally affected by migraine attacks at least twice every month.

The patients used each treatment (candesartan, propranolol or placebo) for 12 weeks.

More than 20 percent of migraine patients reported that they feel better even when they are given a placebo.

Also Read: Why migraines are more common among women

But blind tests show that candesartan works preventively for another 20 to 30 percent of patients.

“The hope is now that candesartan will be even more commonly prescribed,” said Stovner.

Migraines are thought to affect a staggering one billion people worldwide. (IANS)

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Chilli Can Serve As A Valuable Medicine in Case of Lung Cancer

Additional experiments revealed capsaicin suppresses lung cancer metastasis by inhibiting activation of the protein Src. This protein plays a role in the signalling that controls cellular processes like proliferation, differentiation, motility and adhesion.

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In experiments involving three lines of cultured human non-small cell lung cancer cells, researchers observed capsaicin inhibited invasion, the first step of the metastatic process. Pixabay

Besides spicing up your food, chilli, it seems, also has some medicinal value. New research suggests the compound responsible for chilli’s heat could help slow the spread of lung cancer, the leading cause of cancer death for both men and women.

Most cancer-related deaths occur when cancer spreads to distant sites, a process called metastasis.

“Lung cancer and other cancers commonly metastasise to secondary locations like the brain, liver or bone, making them difficult to treat,” said one of the study authors Jamie Friedman from Marshall University in the US.

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They also found mice with metastatic cancer that consumed capsaicin showed smaller areas of metastatic cancer cells in the lung compared with mice not receiving the treatment. Pixabay

“Our study suggests the natural compound capsaicin from chilli peppers could represent a novel therapy to combat metastasis in lung cancer patients,” said Friedman, a doctoral candidate who performed the research in the laboratory of Piyali Dasgupta at Marshall University Joan C. Edwards School of Medicine.

In experiments involving three lines of cultured human non-small cell lung cancer cells, researchers observed capsaicin inhibited invasion, the first step of the metastatic process.

They also found mice with metastatic cancer that consumed capsaicin showed smaller areas of metastatic cancer cells in the lung compared with mice not receiving the treatment.

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Most cancer-related deaths occur when cancer spreads to distant sites, a process called metastasis. Pixabay

The findings were presented during the 2019 Experimental Biology meeting being held from April 6-9 in Orlando, Florida.

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Additional experiments revealed capsaicin suppresses lung cancer metastasis by inhibiting activation of the protein Src. This protein plays a role in the signalling that controls cellular processes like proliferation, differentiation, motility and adhesion.

“We hope one day capsaicin can be used in combination with other chemotherapeutics to treat a variety of lung cancers,” said Friedman. (IANS)