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People who travel around the globe are likely to pick up numerous genes that promote microbial resistance, which can then spread when travelers return home, and potentially initiate a bacterial outbreak, suggests new research.
Researchers, from the Washington University School of Medicine in St. Louis, noted that international travelers often return home with an unexpected bounty of new bacterial strains jostling for position among the thousands that normally reside within the gut microbiome.
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“Even before the Covid-19 pandemic, we knew that international travel was contributing to the rapid global increase and spread of antimicrobial resistance,” said Alaric D’Souza, a doctoral student at the varsity.
“But what’s new here is that we’ve found numerous completely novel genes associated with antimicrobial resistance that suggest a worrisome problem on the horizon,” D’Souza added. The findings are published in the journal Genome Medicine.
Poverty, poor sanitation, and changing agricultural practices have turned many low-income, developing regions into hot spots for diseases spread by bacteria, including infections that are increasingly resistant to a range of antibiotic drug treatments.
For the study, the team analyzed bacterial communities in the gut microbiomes of 190 Dutch adults before and after travel to one of four international regions where the prevalence of resistance genes is high: Southeastern Asia, South Asia, North Africa, and Eastern Africa.
In all, the researchers detected 121 antimicrobial resistance genes across the gut microbiomes. More than 40 percent of these resistance genes were only discovered using the more sensitive metagenomics technique, suggesting that potentially dangerous genes are being missed by the more conventional approaches.
The results also confirmed that 56 unique antimicrobial resistance genes had become part of the travelers’ gut microbiomes during their trips abroad, including several mobiles, high-risk resistance genes, such as extended-spectrum beta-lactamases (ESBL) and the plasmid-borne colistin resistance gene, MCR-1.
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The rapid spread of antimicrobial resistance is one of the most serious public health threats now facing the world — a looming medical catastrophe that could outweigh the chaos created by the Covid-19 pandemic.
“Identifying new antimicrobial-resistant bacteria and genes could play an important role in slowing the global spread of resistance and guide potential treatments for related diseases,” Gautam Dantas, Professor of pathology and immunology at Washington University. (IANS/KB)
(how is covid-19 transmitted, travel during covid-19, coronavirus travel advice, how does microbial resistance occur, types of antimicrobial resistance)
The UK government on Thursday announced that it will move India from the red to the amber list on Sunday, in the country's latest update to the 'Red-Amber-Green' traffic light ratings for arrivals into England amid the Covid-19 pandemic.
This means the visit visas for the UK from India are open, in addition to other long-term visas that have remained open. But travellers from India arriving in England can complete a 10-day quarantine at home or in the place they are staying (not mandatorily quarantine in a managed hotel).
The UK government also announced that arrivals from France to England will no longer need to quarantine if they are fully vaccinated. The step aligns France with the rest of the amber list now that the proportion of beta variant cases has fallen, where those who are fully vaccinated with a vaccine authorised and administered in the UK, the US or Europe do not need to quarantine when arriving in England.
This move also simplifies the system to three categories, as well as the green watch list to give travellers notice where green status is at risk.
To continue cautiously reopening international travel, Austria, Germany, Slovenia, Slovakia, Latvia, Romania and Norway will be added to the government's green list, having demonstrated they posed a low risk to UK public health.
Besides India, Bahrain, Qatar and the UAE will also be moved from the red to the amber list, as the situation in these countries has improved.
The data for all countries will be kept under review and the government will not hesitate to take action where a country's epidemiological picture changes, a statement by the UK government said.
Following an assessment of the latest data, Georgia, La Reunion, Mayotte and Mexico will be added to the red list as they present a high public health risk to the UK from known variants of concern, known high-risk variants under investigation or as a result of very high in-country or territory prevalence of Covid-19.
Arrivals from Spain and all its islands are advised to use a PCR test as their pre-departure test wherever possible, as a precaution against the increased prevalence of the virus and variants in the country.
Transport Secretary Grant Shapps said: "We are committed to opening up international travel safely, taking advantage of the gains we've made through our successful vaccination programme, helping connect families, friends and businesses around the world.
"While we must continue to be cautious, today's changes reopen a range of different holiday destinations across the globe, which is good news for both the sector and travelling public."
Since February, anyone who arrives in the UK from a red list country has been required by law to book a stay in a managed quarantine facility for 10 days.
In order to ensure taxpayers are not subsidising the costs of staying in these facilities, which have gone up, the cost will increase from August 12. Alternative payment arrangements remain available to those who genuinely cannot afford to pay and rates remain the same for children up to 12.(IANS/HP)
A Hindu temple in Pakistan's Punjab province was reportedly vandalized by hundreds of people after a nine-year-old Hindu boy, who allegedly urinated at a local seminary, received bail, a media report said on Thursday.
According to the Dawn news report, the incident took place on Wednesday in Bhong town, about 60 km from Rahim Yar Khan city.
Besides the vandalization, the mob also blocked the Sukkur-Multan Motorway (M-5), the report added.
Citing sources, Dawn news said that a case was registered against the minor on July 24 based on a complaint filed by a cleric, Hafiz Muhammad Ibrahim, of the Darul Uloom Arabia Taleemul Quran.
The sources said that "some Hindu elders did tender an apology to the seminary administration saying the accused was a minor and mentally challenged".
But, when a lower court granted him bail a few days ago, some people incited the public in the town on Wednesday and got all shops there closed in protest, the report quoted the sources as further saying.
A video clip showing people wielding clubs and rods storming the temple and smashing its glass doors, windows, lights, and damaging the ceiling fans went viral on social media.
In response, one Twitter user said: "Ganesh Temple, village Bhong in Rahim Yar Khan, Punjab has been ravaged. Another day, another attack on Hindus in Pakistan."
Another said: "Yesterday, the mob ran amok at Temple over minor boy issue who allegedly urinated, the boy said to be mentally handicapped. Hindu community made an apology for the boy — a case registered against the nine-year-old boy. Those vandalized temples, no FIR registered against them."
District police spokesman Ahmed Nawaz Cheema said Rangers had been deployed in the troubled area and the situation was under control.
A small town close to the River Indus and Sindh-Punjab border, Bhong houses a number of gold traders who originally hail from Ghotki and Dehrki (Sindh), according to the Dawn news report.
A ruling PTI member representing the minority said he had been in touch with the local Hindu community and influential Rais family of Bhong since the issue surfaced.
OṀ KALMASHARAHITABHŨMYAI NAMAH:
OṀ (AUM) -KAL-MA-SHA-RA-HI-TA-BHOO-MYAI— NA-MA-HA
ॐ कल्मषरहितभूम्यै नमः
(Kalmasham: Tainted, blemish, dirty, sinful, wicked, foul, dosha, opprobrium, stigma; Rahita: Absent, devoid of)
Kalmasham is the opposite of purity; it means impure, contaminated and defective. The word is used in several senses such as: defective, fault, sin, dosham, tainted, vice, crime, disrespect, abuse, evil and contamination. However, it is also used in a technical sense in certain fields of knowledge. In Vedic literature we see words like pavitram, and pavitrata in the opposite sense of kalmasham. We, as Hindus, see everything as pure and equitable with God in an implied meaning that every atom at the microscopic level is part of the Supreme Power (Bhagavān). Having this knowledge and understanding, Hindus see the presence of God in living as well as non-living objects and have a pavitra meaning- kalmasharahita bandham.
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In Vedas and Purāṇās, Lord Shri Ramachandra Murty is portrayed without any defects and His marriage with Sīta was described as kalmasharahitam. He was glorified as the one who strictly observed the 'ekapatnī vratam' meaning-'one wife as a life partner'. Even when Sīta was abducted by the demon- Rāvaṇa and he kept her in his palace for a year, Rama did not look at another woman. The same credit goes to His consort and wife Sīta, who came out of Agni (pyre of fire) as a shining diamond proving her chastity and kalmasharahitam to the world. Our sacred literature is full of these incidents. Our dharmaśhāstrās explain that what is kalmasham is that which brings defection to one's purity. They advise purity in our thought, speech and actions.
God Ram and Goddess SitaGetty Pictures
There are many relationships we have as an individual. Some are pure and kalmasharahitam, as opposed to other relationships, like extramarital affairs. The relationship between husband and wife; brother and sister; father and daughter; parents and children; between siblings; teacher and student; among friends; and last but not least, between a devotee and his desired, beloved and personal god are considered kalmasharahitam.
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As a country, we have never waged war against another country with the intention of occupancy and robbing their wealth, or to convert them to our religion. We do not have that kalmasham on our hands or in our hearts.
Our land is 'Kalmasharahita Bhūmi'.