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Many people have suffered excruciating pain from cold because they have a hollow in their tooth that has gone untreated. Pixabay

Ever thought about why cold induces tooth pain and hypersensitivity? Researchers have uncovered odontoblasts, the cells that form a tooth’s dentin, have a newly discovered function — sensing cold — which can trigger pain in teeth.

However, researchers, including Jochen Lennerz from Massachusetts General Hospital, have also found a way to block the pathway to cold-sensitive teeth.


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“We found that odontoblasts, which support the shape of the tooth, are also responsible for sensing cold,” said Lennerz.


Teeth that hurt when exposed to cold can happen for a variety of reasons. Pexels

Teeth that hurt from exposure to cold can occur for many reasons. Many people have experienced intense pain from cold when they have a hole in a tooth from an untreated cavity.

For the study, the team conducted experiments on mice whose molars were drilled under anesthesia.

Mice with dental injuries manifest pain with their behavior; they drink up to 300 percent more sugar water than their littermates without dental injuries, for example.

In previous research, the team of investigators had discovered TRCP5, a protein encoded by the TRCP5 gene that is expressed in nerves in many parts of the body. Their earlier discovery allowed the researchers to zero in on TRCP5 as a mediator of pain from cold.

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By studying genetically altered mice that did not have the TRCP5 gene, the researchers found that the mice with injured teeth did not manifest the increased drinking behavior and behaved like mice without dental injuries.

The research team also identified a pharmacological target for minimizing tooth sensitivity to cold. For centuries, the oil of cloves has been used as a remedy for tooth pain. The active agent in the oil of cloves is eugenol, which happens to block TRCP5. (IANS/KB)


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Rihanna was summoned from her seat to accept the honour, with the Prime Minister.

Singer Rihanna was honoured by Prime Minister Mia Mottley at an event which marked Barbados's new status as a republic, which was attended by Prince Charles. Addressing the pop star by her real name, the PM said: "Robyn Rihanna Fenty tomorrow morning shall have conferred upon her the order of national hero of Barbados."

Rihanna was then summoned from her seat to accept the honor, with the Prime Minister managing to rouse a laugh from the singer when she referenced her 2012 hit 'Diamonds', reports femalefirst.co.uk. She added: "On behalf of a grateful nation, but an even prouder people, we therefore present to you, the designee, for the national hero of Barbados." "And to accept on behalf of a grateful nation - you can come my dear - ambassador Robyn Rihanna Fenty, may you continue to shine like a diamond and bring honor to your nation." Rihanna, who was born in the St Michael parish of Barbados, found fame in 2005 after being spotted by a record producer and has since gone on to become one of the most successful female artists of all time with sales of over 250 million and recently reached billionaire status through her Fenty beauty brand.

The Prime Minister continued in her speech: "Commanding the imagination of the world through the pursuit of excellence, her creativity, her discipline, and above all else, her extraordinary commitment to the land of her birth. "Having satisfied that, Ambassador Robyn Rihanna Fenty has given service to Barbados which has been exemplified by visionary and pioneering leadership, extraordinary achievement and the attaining of the highest excellence to the Government of Barbados." It comes after a historic move for Barbados, which has become a republic after almost 400 years and welcomes its first president, Sandra Mason, after removing Queen Elizabeth as head of state. (IANS/ MBI)


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