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One hemisphere of a healthy brain (L) is pictured next to one hemisphere of a brain of a person suffering from Alzheimer disease. VOA

Managing cholesterol might help reduce Alzheimer’s risk, says researchers, including one of Indian-origin, who identified a genetic link between the progressive brain disorder and heart disease.

Examining DNA from more than 1.5 million people, the study showed that risk factors for heart disease such as elevated triglyceride and cholesterol levels (HDL, LDL, and total cholesterol) were genetically related to Alzheimer’s risk.


However, genes that contribute to other cardiovascular risk factors, like body mass index and Type-2 diabetes, did not seem to contribute to genetic risk for Alzheimer’s.


Alzheimer’s disease patient Isidora Tomaz, 82, sits in an armchair in her house in Lisbon, Portugal. It’s predicted that by 2050, 135 million Americans are going to suffer from mild cognitive impairment, a precursor of Alzheimer’s. VOA

“The genes that influenced lipid metabolism were the ones that also were related to Alzheimer’s disease risk,” said Celeste M. Karch, Assistant Professor at the Washington University’s School of Medicine.

Thus, if the right genes and proteins could be targeted, it may be possible to lower the risk for Alzheimer’s disease in some people by managing their cholesterol and triglycerides, added Rahul S. Desikan, Assistant Professor at the UCSF.

For the study, published in the journal Acta Neuropathologica, the team

identified points of DNA that increase the risk of cardiovascular disease and also heighten the risk for Alzheimer’s disease.


AI technique can boost brain scans to predict Alzheimer early. Pixabay

The team looked at differences in the DNA of people with factors that contribute to heart disease or Alzheimer’s disease and identified 90 points across the genome that were associated with risk for both diseases.

Their analysis confirmed that six of the 90 regions had very strong effects on Alzheimer’s and heightened blood lipid levels, including several within genes that had not previously been linked to dementia risk.

These included several points within the CELF1/MTCH2/SPI1 region on chromosome 11 that previously had been linked to the immune system.

Also Read: AI Technique to Improve Brain Scans To Predict Alzheimer’s Early

The researchers confirmed their findings in a large genetic study of healthy adults by showing that these same risk factors were more common in people with a family history of Alzheimer’s, even though they had not themselves developed dementia or other symptoms such as memory loss.

“These results imply that cardiovascular and Alzheimer’s pathology co-occur because they are linked genetically. That is, if you carry this handful of gene variants, you may be at risk not only for heart disease but also for Alzheimer’s,” Desikan said. (IANS)


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Photo by Pixabay

Upcoming medical colleges in Uttar Pradesh will be named after saints and sages

The new medical colleges being opened in Uttar Pradesh will be named after saints and sages.

The state government has issued an order naming four district hospitals that are being converted into medical colleges.

These district hospitals are in Bijnor, Fatehpur, Chandauli, and Siddharth Nagar.

The Bijnor medical college has been named after Mahatma Vidur, a philosopher during the Mahabharata era and uncle of the Pandavas and Kauravas.

The Chandauli medical college has been named after Baba Keenaram, said to be the founder of the Aghori sect.

The Siddharth Nagar district hospital will be called Madhav Prasad Tripathi Medical College after the BJP politician from the region. Tripathi, popularly known as Madhav Babu, was also the first Uttar Pradesh BJP chief. He was elected MP from Domariyaganj in 1977, besides being two times Jan Sangh MLA and also a member of the UP legislative council.

The Fatehpur hospital has been named Amar Shaheed Jodha Singh Ataiya Thakur Dariyawn Singh Medical College, after the freedom fighter of 1857.

It is said that he was among the first to use Guerrilla warfare against the British, as taught by freedom fighter Tatya Tope.

Meanwhile, according to official sources, the medical college in Deoria will be named after Maharishi Devraha Baba and the medical college of Ghazipur in the name of Maharishi Vishwamitra.

The medical college of Mirzapur will be in the name of Maa Vindhyavasini, the medical college of Pratapgarh in the name of Dr. Sonelal Patel and the medical college of Etah will be named after Veerangana Avantibai Lodhi. (IANS/JB)

Keywords: Medical Colleges, Uttar Pradesh, Yogi Adityanath, India, Politics


Photo by Wikimedia Commons

Photo of Indian cricket team on the ground

Former Pakistan captain Inzamam-ul-Haq has picked India as the favourite to win the ongoing ICC Men's T20 World Cup in Oman and United Arab Emirates (UAE).

Inzamam feels that the Virat Kohli-led India have a greater chance of winning the trophy as the conditions in the Gulf nations are similar to the subcontinent, which makes India the most dangerous side in the event, according to Inzamam.

"In any tournament, it cannot be said for certain that a particular team will win' It's all about how much chance do they have of winning it. In my opinion, India have a greater chance than any other team of winning this tournament, especially in conditions like these. They have experienced T20 players as well," said Inzamam on his YouTube channel.

He said more than the Indian batters, the bowlers have a lot of experience of playing in the conditions. The Indian Premier League (IPL) was played recently in UAE and most of the Indian bowlers did well in that leg.

Inzy heaped praises on the Men in Blue for the confident manner in which they chased the target against Australia on a challenging track without needing Kohli's batting prowess.

"India played their warm-up fixture against Australia rather comfortably. On subcontinent pitches like these, India are the most dangerous T20 side in the world. Even today, if we see the 155 runs they chased down, they did not even need Virat Kohli to do so," he added.

Though he did not pick any favourite, Inzamam termed the India-Pakistan clash in the Super 12 on October 24 as the 'final before the final' and said the team winning it will go into the remaining matches high on morale,

"The match between India and Pakistan in the Super 12s is the final before the final. No match will be hyped as much as this one. Even in the 2017 Champions Trophy, India and Pakistan started and finished the tournament by facing each other, and both the matches felt like finals. The team winning that match will have their morale boosted and will also have 50 percent of pressure released from them," Inzamam added. (IANS/JB)

Keywords: India, Pakistan, Sports, ICC T20 World Cup, UAE.


Photo by Diana Akhmetianova on Unsplash

Skin problems like itchiness, dryness and flakiness can occur anytime if you're not moisturising your body enough.

Skin problems like itchiness, dryness and flakiness can occur anytime if you're not moisturising your body enough. It is commonly observed that while many people take their skincare routine seriously, a majority of them neglect to moisturise the body. It is important to keep in mind that timing matters a lot when it comes to applying moisturisers. Therefore, knowing the appropriate time to apply body lotion is essential.

Take a look at the ideal times to moisturise your body shared by Kimi Jain, Head of Retail, KIMRICA.

Morning
Moisturising the body in the morning sets your skin up to face countless irritants and environmental factors during the day. The skin is constantly exposed to harsh chemicals and pollutants when you're outside which is why using a protective and soothing moisturiser while going out is necessary. Kimirica's Five Elements Body Lotion comes with natural Aloe Vera extracts that act as a rich source of antioxidants and vitamins that helps protect your skin and provide a deep nourishing effect.

man in white crew neck t-shirt Moisturising the body in the morning sets your skin up to face countless irritants and environmental factors during the day. | Photo by The Creative Exchange on Unsplash

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