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Researchers have discovered that supplementing existing antiretroviral therapy with a natural compound can reduce the potency of the human immunodeficiency virus (HIV), thereby halting the progression of AIDS.

HIV-infected patients remain on antiretroviral therapy for life because the virus survives over the long-term in infected dormant cells. Interruption of current types of antiretroviral therapy results in a rebound of the virus and clinical progression to AIDS.


“O


ur results highlight an alternative approach to current anti-HIV strategies,” said lead researcher Susana Valente, associate professor at The Scripps Research Institute (TSRI) in the US.

In the study published in the journal mBio, the researchers have detailed that unlike other antiretroviral therapies, a natural compound called Cortistatin A reduces residual levels of virus from the HIV-infected dormant cells, establishing a near-permanent state of latency and greatly diminishing the virus’ capacity for reactivation.

“Prior treatment with Cortistatin A significantly inhibits and delays viral rebound in the absence of any drug,” Valente noted.

“Our results suggest current antiretroviral regimens could be supplemented with a Tat inhibitor such as Cortistatin A to achieve a functional HIV-1 cure, reducing levels of the virus and preventing reactivation from latent reservoirs,” Valente explained.

For the study, the researchers isolated cells from nine HIV-infected participants being treated with antiretroviral drugs.

They found that treatment with the natural molecule reduced viral reactivation by an average of 92.3 percent. (IANS)


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Beauty icons Kriti Sanon and Shanaya Kapoor believe in natural and clean beauty products.

Clean beauty products are making inroads and have gained a significant share of the beauty market, with more more people becoming aware of the their benefits. With each passing year thanks to technology, research and development natural ingredients have finally regained their place in the spotlight. Don't take our word for it, beauty icons Kriti Sanon and Shanaya Kapoor also believe in natural and clean beauty products, and associate with the 'Naturali' range launched by RP-Sanjiv Goenka Group. The new age nature-inspired personal care brand aims to provide a one-of-a kind experience to their customer infused with trendy natural ingredients delivering quick visible results.

Hair care ambassador Kriti Sanon said, 'I am extremely thrilled to be associating with Naturali haircare range that is infused with modern, trendy natural ingredients which are free from harmful chemicals. I have always been an ardent supporter of the 'no nasties' proposition when it comes to my hair care needs, hence this association came very naturally to me. Everyone knows that natural products are supposed to be good for you, but they are often believed to be slow in giving results. Naturali changes this, as the range has a unique SuperBlend of complementary natural ingredients, that are optimized to give you quick visible results. As a woman myself, I strongly believe that no woman should ever have to compromise especially with respect to her beauty choices. So, it is extremely fulfilling to see a brand that is not only good for you being free from harmful chemicals but also makes you look good.'

sliced fruit on white surface Clean beauty products are making inroads and have gained a significant share of the beauty market, with more more people becoming aware of the their benefits. | Photo by Brooke Lark on Unsplash

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