Thursday August 16, 2018

Obesity Alone Does not Increase Death Risk: Study

Earlier, a study, published in The Lancet Diabetes and Endocrinology journal, found that women with metabolically healthy obesity were at 39 per cent higher risk of cardiovascular disease

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The researchers looked at how many people within each group died as compared to those within the normal weight population with no metabolic risk factors.
The researchers looked at how many people within each group died as compared to those within the normal weight population with no metabolic risk factors. Pixabay
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Patients who have metabolically healthy obesity but are free from other metabolic risk factors do not have an increased rate of mortality, a new study has found.

Metabolically healthy obesity is a debatable medical condition characterized by obesity which does not produce metabolic complications.

The study, published in the journal Clinical Obesity, showed that unlike dyslipidemia, hypertension and diabetes — each one of which is related to high mortality risk — obesity alone does not pose any threat to life.

“We are showing that individuals with metabolically healthy obesity are actually not at an elevated mortality rate,” said lead author Jennifer Kuk, Associate Professor at the York University in Canada.

“We found that a person of normal weight with no other metabolic risk factors is just as likely to die as the person with obesity and no other risk factors,” Kuk added.

Metabolically healthy obesity is a debatable medical condition characterized by obesity which does not produce metabolic complications.
Metabolically healthy obesity is a debatable medical condition characterized by obesity which does not produce metabolic complications. Pixabay

For the study, the research team followed 54,089 men and women from five cohort studies who were categorized as having obesity alone or clustered with a metabolic factor, or elevated glucose, blood pressure or lipids alone or clustered with obesity or another metabolic factor.

The researchers looked at how many people within each group died as compared to those within the normal weight population with no metabolic risk factors.

They found that one out of 20 individuals with obesity had no other metabolic abnormalities.

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“This is in contrast with most of the literature and we think this is because most studies have defined metabolic healthy obesity as having up to one metabolic risk factor,” said Kuk.

“This is clearly problematic, as hypertension alone increases your mortality risk and past literature would have called these patients with obesity and hypertension, ‘healthy’. This is likely why most studies have reported that ‘healthy’ obesity is still related with higher mortality risk,” Kuk noted.

Earlier, a study, published in The Lancet Diabetes and Endocrinology journal, found that women with metabolically healthy obesity were at 39 per cent higher risk of cardiovascular disease. (IANS)

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Obesity During Pregnancy May up Kids’ Risk of Epilepsy

In addition, complications related to neonatal-asphyxia -- the state of being deprived of oxygen --, as well as less severe neonatal complications, were also independently associated with increased risk of childhood epilepsy

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The risk for children with mothers in the grade III obesity category was 82 per cent. Pixabay

Women who are overweight or obese during their pregnancy may significantly increase the risk for children developing epilepsy, a study has showed.

Epilepsy is a disorder in which nerve cell activity in the brain is disturbed, causing seizures.

The results showed that the risk of epilepsy increased by 11 per cent in children of overweight mothers (BMI of 25 to less than 30) compared with children and normal-weight mothers.

While women with grade I obesity (BMI 30 to less than 35) increased the risk 20 by per cent, those with grade II obesity (BMI 35 to less than 40) raised the risk by 30 per cent.

The risk for children with mothers in the grade III obesity category was 82 per cent.

Pregnancy
Representational image. Pixabay

“Given that overweight and obesity are potentially modifiable risk factors, prevention of obesity in women of reproductive age may be an important public health strategy to reduce the incidence of epilepsy,” said Neda Razaz, from the Karolinska Institutet in Sweden.

Maternal overweight and obesity may increase the risk of brain injury, leading to a range of neurodevelopmental disorders, or that maternal obesity might affect neurodevelopment through obesity-induced inflammation, leading to epilepsy, the researchers argued, in the article published online by JAMA Neurology.

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In addition, complications related to neonatal-asphyxia — the state of being deprived of oxygen –, as well as less severe neonatal complications, were also independently associated with increased risk of childhood epilepsy. (Bollywood Country)