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The researchers discovered that the enzyme NADPH Oxidase is critically important for the generation of free radicals, the stimulation of blood clotting and the promotion of blood vessel damage in patients. Pixabay

Scientists have developed a new technique that allows them to measure blood clotting as well as the formation of free radicals, that leads to the build-up of blood clots, which in turn cause heart disease, stroke and dementia.

The technique, led by the University of Exeter researchers, investigates a part of the blood clotting process which focuses on the ways in which platelets from blood samples clump together.


“This method may be useful for future studies looking into new anti-platelet treatments for diseases such as diabetes, where clotting is disturbed and increases the risk of heart attack or stroke,” according to the study detailed in the Haematologica journal.


The technique, led by the University of Exeter researchers, investigates a part of the blood clotting process which focuses on the ways in which platelets from blood samples clump together. Pixabay

The researchers discovered that the enzyme NADPH Oxidase is critically important for the generation of free radicals, the stimulation of blood clotting and the promotion of blood vessel damage in patients.

They successfully used the technique in mice and human cells. Their aim is to better understand how blood cells function, which will help to develop new drugs against blood clotting diseases or to test the risk of clotting diseases in patients.

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“We’re really excited to discover this new technique and its potential to understand how blood vessel diseases develop. For the first time, we can now simultaneously measure blood clotting and the formation of free radicals,” said lead author Giordano Pula, from the Exeter Medical School.

“We know they play a key role in blood vessel damage caused by ageing, diabetes, obesity and chronic inflammation. We’re currently using this technique in our efforts to develop a new treatment to protect the blood vessels in diseases such as heart diseases, stroke, obesity, and vascular dementia,” Pula added. (IANS)


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Basil Leaves

Basil scientifically called Ocimum basilicum, and also known as great basil, is a culinary herb from the Lamiaceae (mints) family. A common aromatic herb, it is usually used to add flavor to a variety of recipes, but what may astonish one is that there are various health benefits of basil that make it well-known for its immunity-enhancing properties.

Basil seeds or basil essential oil are proven to help prevent a wide range of health conditions, which makes it one of the most essential medical herbs known today. Basil has vitamin A, C, E, K, and Omega 3 components including cooling components too. It also contains minerals like Copper, Calcium, Manganese, Phosphorus, Zinc, and Potassium. An ancient Ayurvedic herb, basil has various proven benefits including being anti-inflammatory, ant-oxidant, immune-booster, pain-reducer, and blood vessel-protector.

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This herb also contains cooling components thus making it really helpful for summers. It detoxifies the body and maintains one's body temperature pace. Adding to the benefits Basil contains antioxidant-rich volatile essential oils, which are considered hydrophobic, meaning they don't dissolve in water and are light and small enough to travel through the air and the pores within our skin. Basil's volatile essential oil is something that gives the herb its distinct smell and taste, but basil contains some great healing properties.

In the long history of Ayurveda, basil seeds were also called tukmaria seeds. These seeds may support one's gut health, may complete one's fiber quota, reduce blood sugar, help in weight loss, and also reduce cholesterol.

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When you're pregnant, the immune system is seeing the placenta for the first time in decades.

The US researchers have discovered a class of immune cells that plays a role in miscarriage, which affects about a quarter of pregnancies.

Researchers at the University of California-San Francisco found that the recently discovered subset of cells known as extrathymic Aire-expressing cells in the immune system may prevent the mother's immune system from attacking the placenta and fetus.

The researchers showed that pregnant mice who did not have this subset of cells were twice as likely to miscarry, and in many of these pregnancies fetal growth was severely restricted.

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"When you're pregnant, the immune system is seeing the placenta for the first time in decades -- not since the mother made a placenta when she herself was a fetus," said Eva Gillis-Buck, from UCSF.

"Our research suggests that this subset of immune cells is carrying out a sort of 'secondary education' -- sometimes many years after the better-known population of the educator cells have carried out the primary education in the thymus -- teaching T cells not to attack the fetus, the placenta and other tissues involved in pregnancy," she added. The findings are published in the journal Science Immunology.

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