Tuesday March 26, 2019

Weight Loss Tip- Chinese Medicine Ingredient May Help Reduce Obesity

Overweight and obesity may increase the risk of many health problems, including diabetes, heart diseases and certain cancers

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Weight Loss
Here's the secret to maintaining weight loss. Pixabay

A herbal ingredient used in traditional Chinese medicines may help you to reduce your body weight, a new study has found.

The scientists were able to show that the herbal active substance, celastrol — used in Chinese medicines — leads to a significant weight loss and an improvement of diabetes in obese mice, Xinhua news agency reported on Saturday.

The findings showed the celastrol specifically activates satiety centres in the brain, which play a central role in the control of body weight.

“Normally, those affected lose their satiety because the corresponding hormone leptin no longer works. The drug celastrol we investigated restores leptin sensitivity and hence satiety,” said lead author Katrin Pfuhlmann from Helmholtz Zentrum Munchen – German Research Centre for Environmental Health.

The study, published in the journal Diabetes, observed a significantly altered eating behaviour in overweight animals.

Weight loss
Representational image. Pixabay

“The administration of celastrol resulted in significantly reduced food intake in the mouse model. Accordingly, we were able to determine an average loss of about 10 per cent body weight within a week,” the researchers said.

To what extent the findings can also be confirmed in humans is still unclear, according to the authors. However, study leader Pfluger is confident, “The satiety hormone leptin in humans and the mouse is almost identical, so celastrol has great potential,” the report said.

The clinical trials are currently under way in the US.

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“The satiety hormone leptin in humans and the mouse is almost identical, so celastrol has great potential,” the researcher said.

Overweight and obesity may increase the risk of many health problems, including diabetes, heart diseases and certain cancers. (IANS)

Next Story

Obesity Can Result in Early Onset of Puberty: Study

Controlling the obesity epidemic in children could be useful in decreasing these risks, Mericq noted

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Obesity
An overweight woman sits on a chair in Times Square in New York, May 8, 2012. VOA

Obese boys and girls are likely to enter puberty at an early age, which can result in stunted growth or depression, finds a new study.

The study showed total body obesity and excess belly fat in boys aged four-seven years were associated with greater odds of starting puberty before age nine.

“With the increase in childhood obesity worldwide, there has been an advance in the age at which puberty begins in girls. But in boys the evidence has been controversial,” said lead researcher, Maria Veronica Mericq, Professor from the University of Chile.

The study that will be presented at the ongoing ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, the US.

For the study, the researchers included 527 Chilean boys.

Obesity can now be cured by our body's natural weighing scales.
Obesity can now be cured by our body’s natural weighing scales.

Among boys aged five or six, those with obesity had nearly 2.7 times the odds of starting puberty early. Whereas those with excess belly fat had almost 6.4 higher odds of puberty before age nine, said Mericq.

She said excess belly fat more closely related to fat mass, because a higher BMI may reflected increased muscle, especially in athletes.

Precocious or early puberty has been linked to possible problems, including stunted growth, emotional-social problems like increased risks of depression and substance abuse.

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In addition, in boys, it could lead to higher incidence of testicular cancer in adulthood, said Mericq.

Controlling the obesity epidemic in children could be useful in decreasing these risks, Mericq noted. (IANS)