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Many molecules can cause inflammation. Pixabay

Human muscle has an innate ability to ward off the damaging effects of chronic inflammation when exercised, a new study suggests. The study, published in the journal Science Advances, indicates that inflammation is not inherently good or bad. When the body is injured, an initial low-level inflammation response clears away debris and helps tissue rebuild.

“Our engineered muscle platform is modular, meaning we can mix and match various types of cells and tissue components if we want to. But in this case, we discovered that the muscle cells were capable of taking anti-inflammatory actions all on their own,” said researcher Nenad Bursac, Professor at Duke University.


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Among many molecules that can cause inflammation, one pro-inflammatory molecule, in particular, interferon-gamma, has been associated with various types of muscle wasting and dysfunction. While previous research in humans and animals has shown that exercise can help mitigate the effects of inflammation in general, it has been difficult to distinguish what role the muscle cells themselves might play, let alone how they interact with specific offending molecules, such as interferon-gamma.


Exercise can help mitigate the effects of inflammation in general. Pixabay

To prove that muscle alone is capable of blocking interferon gamma’s destructive powers, the team turned to an engineered muscle platform that the laboratory has been developing for nearly a decade. They were first to grow to contract, functional human skeletal muscle in a Petri dish, and since then the lab has been improving its processes by, for example, adding immune cells and reservoirs of stem cells to the recipe.

ALSO READ: Hormone Ghrelin May Protect The Elderly Population From Muscle Loss

In the current study, the researchers took these fully functional, lab-grown muscles and inundated them with relatively high levels of interferon-gamma for seven days to mimic the effects of a long-lasting chronic inflammation. As expected, the muscle got smaller and lost much of its strength.

The researchers then applied interferon-gamma again, but this time also put it through a simulated exercise regime by stimulating it with a pair of electrodes. While they expected the procedure to induce some muscle growth, as shown in their previous studies, they were surprised to discover that it almost completely prevented the effects of the chronic inflammation. (IANS)


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Photo by Wikimedia Commons

Japan launched its new satellite, QZS-1R.

Japan has successfully launched a new navigation satellite into orbit that will replace its decade-old navigation satellite.

The satellite, QZS-1R, was launched onboard an H-2A rocket that lifted off from the Tanegashima Space Center at 10.19 p.m. on Monday night, Mitsubishi Heavy Industries said in a statement.

The company builds and operates H-2A rockets the Japan Aerospace Exploration Agency (JAXA).

QZS-1R is a replacement for Quasi-Zenith Satellite System 1 satellite first launched in 2010. “It was a really beautiful launch," the company said in a tweet after a successful lift-off.

"H-IIA F44 flight proceeded nominally. Approximately 28 minutes 6 seconds after launch, as planned, the payload separated from the launch vehicle," the statement said.

The official QZSS website lists four satellites in the constellation: QZS-1, QZS-2, QZS-3 and QZS-4, Space.com reported.

The QZSS constellation will eventually consist of a total of seven satellites that fly in an orbit passing through a near-zenith (or directly overhead) above Japan, and QZS-R1 is meant to share nearly the same transmission signals as recent GPS satellites, according to JAXA.

It is specially optimised for mountainous and urban regions in Japan, JAXA said.

Mitsubishi's H-2A 202 rocket launch system has been operational since 2003 and has sent satellites to locations such as Venus (Akatsuki) and Mars (Emirates Mars Mission).

The latest H2-A rocket launch is the first since November 29, 2020, when Japan launched an advanced relay satellite with laser communications tech into orbit, the report said. (IANS/JB)


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Photo by Mike Enerio on Unsplash

Fireworks light up the night sky

Everyone loves firecrackers, even the most environment-friendly advocates cannot hide their joy when they see these delightful lights colour the skies. India celebrates Diwali in the true spirit of her culture and heritage by spraying the navy-blue skies with sparkling hues of gold, silver, red, and green. Firecrackers are not just a tradition in this country, they are a legacy.

The original connotation one makes with fireworks in China. The elaborate Chinese celebrations with dragons and zapping firecrackers have left their mark in human memory, but the use of fireworks is not limited to heralding the Chinese New Year. All over the world, fireworks have come to symbolise the ultimate celebration. During Diwali in India, this spirit is re-ignited every year.

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A visitor looks at statues of the 'Royal treasures of Abomey kingdom' on display at the Musee du quai Branly in Paris on Sept. 10, 2021, part of 26 artworks set to be restituted to Benin later in the year.

PARIS — In a decision with potential ramifications across European museums, France is displaying 26 looted colonial-era artifacts for one last time before returning them home to Benin.

The wooden anthropomorphic statues, royal thrones and sacred altars were pilfered by the French army in the 19th century from Western Africa.

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