Wednesday, February 24, 2021
Home Life Style Health & Fitness Exercising Muscle May Ward Off Chronic Inflammation On Its Own

Exercising Muscle May Ward Off Chronic Inflammation On Its Own

The study, published in the journal Science Advances, indicates that inflammation is not inherently good or bad

Human muscle has an innate ability to ward off the damaging effects of chronic inflammation when exercised, a new study suggests. The study, published in the journal Science Advances, indicates that inflammation is not inherently good or bad. When the body is injured, an initial low-level inflammation response clears away debris and helps tissue rebuild.

“Our engineered muscle platform is modular, meaning we can mix and match various types of cells and tissue components if we want to. But in this case, we discovered that the muscle cells were capable of taking anti-inflammatory actions all on their own,” said researcher Nenad Bursac, Professor at Duke University.

Follow NewsGram on Facebook to stay updated.

Among many molecules that can cause inflammation, one pro-inflammatory molecule, in particular, interferon-gamma, has been associated with various types of muscle wasting and dysfunction. While previous research in humans and animals has shown that exercise can help mitigate the effects of inflammation in general, it has been difficult to distinguish what role the muscle cells themselves might play, let alone how they interact with specific offending molecules, such as interferon-gamma.

muscle
Exercise can help mitigate the effects of inflammation in general. Pixabay

To prove that muscle alone is capable of blocking interferon gamma’s destructive powers, the team turned to an engineered muscle platform that the laboratory has been developing for nearly a decade. They were first to grow to contract, functional human skeletal muscle in a Petri dish, and since then the lab has been improving its processes by, for example, adding immune cells and reservoirs of stem cells to the recipe.

ALSO READ: Hormone Ghrelin May Protect The Elderly Population From Muscle Loss

In the current study, the researchers took these fully functional, lab-grown muscles and inundated them with relatively high levels of interferon-gamma for seven days to mimic the effects of a long-lasting chronic inflammation. As expected, the muscle got smaller and lost much of its strength.

The researchers then applied interferon-gamma again, but this time also put it through a simulated exercise regime by stimulating it with a pair of electrodes. While they expected the procedure to induce some muscle growth, as shown in their previous studies, they were surprised to discover that it almost completely prevented the effects of the chronic inflammation. (IANS)

STAY CONNECTED

19,120FansLike
362FollowersFollow
1,773FollowersFollow

Most Popular

Study: Teens May Be More Likely To Be Bullied By Their Friends

Adolescents and teens may be more likely to be bullied by their friends or friends-of-friends than peers who are not closely linked, a new...

10 Health Benefits Of Mint Leaves That One Must Know

Pudina (mint) is one of the oldest culinary herbs known to humans. It has remarkable medicinal properties and is a rich source of polyphenols....

The Job Market Still Looks Bleak In India After A Pandemic-Hit 2020

While the job market still looks bleak in India after a pandemic-hit 2020, the world's professional network LinkedIn said on Wednesday it has seen...

How The 2021 Union Budget Can Impact The Share Market In Future

By Prajakta Pingulkar Share market for beginners is a whole new territory to explore. The market speculation going throughout the year puts many new investors...

Light Intensity Physical Activity May Protect Mobility In Older Women

Light-intensity physical activity, including gardening, shopping, or a casual walk may protect mobility in older women, suggests a new study. The study indicated that...

Fat Cells May Influence How Body Reacts To Heart Failure

Limiting the amount of fat the body releases into the bloodstream from fat cells during heart failure could help improve outcomes for patients, say,...

An Initiative For A Drug Free India

Every year, the birth anniversary of Mahatma Gandhi is observed as National Anti-Drug Addiction Day to honor his commitment towards eradicating the menace of...

A Therapy To Rescue You From Depression And Out Of Work Load

If depression is making it more difficult for some unemployed people to land a job, one type of therapy may help, research suggests. The...

Recent Comments