Never miss a story

Get subscribed to our newsletter


×
Antibiotics may not be good for newborns. Pixabay

Exposure to antibiotics in utero and infancy can lead to an irreversible loss of regulatory T-cells in the colon, a valuable component of the immune system’s response toward allergens in later life, after only six months, finds new research. T cell is a type of white blood cell that is of key importance to the immune system and is at the core of adaptive immunity, the system that tailors the body’s immune response to specific pathogens.

According to the study, published in the journal mBio, it is already known that the use of antibiotics early in life disrupts the intestinal microbiota, the trillions of beneficial microorganisms that live in and on our bodies, that play a crucial role in the healthy maturation of the immune system and the prevention of diseases, such as obesity and inflammatory bowel disease.


Follow NewsGram on Instagram to keep yourself updated.

However, less is known about how disruption of the microbiota, which produces short-chain fatty acids that regulate T-cells, affects T-cells in the colon. “By studying the exposure to newborns through lactating mothers, we see how the offspring acquire their mothers’ antibiotic-impacted microbiota, which compromises their ability to generate a pool of CD41 T cells in the colon, resulting in long-term damage,” said researcher Martin Blaser from the Rutgers University.

ALSO READ:Covid Vaccine In 3rd Trimester Can Transfer Antibodies To Newborns

“The consequences persist into adulthood, compromising the body’s ability to turn off allergic responses,” Blaser added. For the study, based on a mouse model, the team looked at fetal and newborn exposure to antibiotics through the mother in the weeks immediately preceding and after birth, the time when microbial communities assemble and are prone to disruptions, to investigate how this reduction in beneficial bacteria affects neonatal immune system development.

These effects were specific to the colon and not observed in the lungs, upper gastrointestinal tract, or spleen, the researchers said. (IANS/SP)


Popular

Unsplash

Afghans were by far the largest group of applicants in the EU in September.

Afghans lodged more than 17,000 asylum applications in the EU in September, up from 10,000 in August and nearly twice as many as Syrians. This made Afghanistan by far the main country of origin, which Syria had been for seven years until July, the European Asylum Support Office (EASO) said.


Total applications in the EU exceeded pre-pandemic levels for the first time since the outbreak of Covid-19.

Keep Reading Show less
Photo by @shawnanggg on Unsplash

Aviation has revolutionised tourism and business forever, not to mention the cultural linkages that have been made possible.

“When once you have tasted flight, you will forever walk the earth with your eyes turned skyward, for there you have been, and there you will always long to return.” – Leonardo DaVinci

International Civil Aviation Day is observed on December 7th to recognize the flying industry’s impact on modern society. In 1994, as part of ICAO’s (International Civil Aviation Organization) 50th-anniversary celebrations, the first International Civil Aviation Day was observed, and in 1996, the United Nations General Assembly declared December 7th as International Civil Aviation Day.

Keep Reading Show less

Incomplete data entries and loopholes in the ledger are significant factors in slowing down the accounting process.

By- Harris Scott

Business owners hardly have time to look into all aspects of a business operation, and accounting is one aspect. While small business owners might invest some time handling accounting services, it is indeed a big waste for owners of major enterprises. Regardless of the size of the business, your organization needs someone to look after the ledger.

Keep reading... Show less