Never miss a story

Get subscribed to our newsletter


×
The volunteers were randomly divided into two groups, one of which was given vitamin D3 in a single dose of 200,000 units (IU) dissolved in a peanut oil solution. Pixabay

Scientists now report that a high dose of vitamin D administered on admission to the hospital has failed to improve the condition of patients with moderate or severe Covid-19. A clinical trial was conducted in Brazil with 240 patients who were given 200,000 IU of vitamin D3 on admission to the hospital. The supplementation did not reduce the length of stay or affect the proportion requiring intensive, according to the study published in the Journal of the American Medical Association (JAMA).

In vitro studies or trials with animals had previously shown that in certain situations vitamin D and its metabolites can have anti-inflammatory and anti-microbial effects, as well as modulating the immune response.


Follow NewsGram on Twitter to stay updated about the World news.

“We decided to investigate whether a high dose of the substance could have a protective effect in the context of an acute viral infection, reducing either the inflammation or the viral load,” said Rosa Pereira, principal investigator for the project at the University of Sao Paulo’s Medical School (FM-USP). The volunteers were randomly divided into two groups, one of which was given vitamin D3 in a single dose of 200,000 units (IU) dissolved in a peanut oil solution. The other group was given only the peanut oil solution.


The supplementation did not reduce the length of stay or affect the proportion requiring intensive, according to the study published in the Journal of the American Medical Association. Pixabay

All participants were treated according to the standard protocol for hospital treatment of the disease, which includes the administration of antibiotics and anti-inflammatory drugs. The main purpose was to see if acute supplementation would affect the length of hospital stay for these patients, but the researchers also wanted to find out whether it would mitigate the risks of admission to the intensive care unit (ICU), intubation, and death.

No significant difference between the groups was observed for any of these clinical outcomes. According to Pereira, the study was designed above all to assess the impact on hospital stay and a larger number of volunteers would be needed to achieve a scientifically acceptable estimate of the effect on mortality.

ALSO READ: This Molecule Helps Covid-19 Escape Antibodies

“So far we can say there’s no indication to administer vitamin D to patients who come to the hospital with severe Covid-19,” she said. Pereira is currently leading a study to find out whether subjects with sufficient circulating levels of vitamin D combat infection by SARS-CoV-2 better than those with insufficient levels of the nutrient.

The ideal level of vitamin D in the blood and the daily supplementation dose varies according to age and overall health, she explained.”The ideal approach is case-by-case analysis, if necessary, dosing the substance periodically by means of blood work, with supplementation if a deficiency is detected,” Pereira said. (IANS/JC)


Popular

Pinterest

Ancient India not only made mentions of homosexuality but accepted it as well.


The LGBTQ+ acronym stands for Lesbian, Gay, Bisexual, Transgender, Queer, and others. In India LGBTQ+ community also include a specific social group, part religious cult, and part caste: the Hijras. They are culturally defined either as "neither men nor women" or as men who become women by adopting women's dress and behavior. Section 377 of the India Penal code that criminalized all sexual acts "against the order of nature" i.e. engaging in oral sex or anal sex along with other homosexual activities were against the law, ripping homosexual people off of their basic human rights. Thus, the Indian Supreme Court ruled a portion of Section 377 unconstitutional on 6th September 2018.

Keep Reading Show less
wikimedia commons

A stamp depicting the Mysore peta

The Mysore kingdom became a popular tourist destination after India became an independent country. The Wodeyar dynasty who succeeded Tipu Sultan are still royalty, but they do not rule the state. Their heritage and culture have become what Karnataka is famous for.

Among the many things that Mysore offers to the state of Karnataka, the Mysore Peta is one. In north India, various cultures have their own headgears. They wear their traditional outfits on the days of festivities and ceremonies. Likewise, in the south, especially in Karnataka, the Mysore Peta is worn.

Keep Reading Show less
Photo by Wikimedia Commons

Indian author and feminist, Kamla Bhasin passed away at the agr of 74.

Renowned feminist activist, author, and a face of the women's rights movement in India, Kamla Bhasin, passed away today morning at the age of 74.

The news of the same was shared by activist Kavita Srivastava on Twitter. The tweet said, "Kamla Bhasin, our dear friend, passed away around 3am today 25th Sept. This is a big setback for the women's movement in India and the South Asian region. She celebrated life whatever the adversity. Kamla you will always live in our hearts. In Sisterhood, which is in deep grief."

Keep reading... Show less