Never miss a story

Get subscribed to our newsletter


×
Indian Origin Researcher part of team that developed a Test sensitive enough to detect “hidden” HIV. VOA

New York, May 30, 2017: American researchers, including one of Indian origin, have developed a test that is sensitive enough to detect “hidden” HIV and yet is faster, less labour-intensive and less expensive than the current “gold standard” test.

HIV virus has a knack for lying dormant in immune cells at levels undetectable to all but the most expensive and time-consuming tests.


“Globally there are substantial efforts to cure people of HIV by finding ways to eradicate this latent reservoir of virus that stubbornly persists in patients, despite our best therapies,” said senior author Phalguni Gupta, Professor at University of Pittsburgh in the US.

Check out NewsGram for latest international news updates.

“But those efforts aren’t going to progress if we don’t have tests that are sensitive and practical enough to tell doctors if someone is truly cured,” Gupta said.

HIV spreads by infecting CD4+ T cells, which are a type of white blood cell that plays a major role in protecting the body from infection.

Once HIV therapy is working, it becomes critical to determine if the HIV DNA being detected by a test could actually create more virus and cause the person to relapse if therapy is stopped.

Follow NewsGram on Facebook

Therefore, the test must be able to show that the virus it detects can replicate — typically by growing the virus from the sample.

To date, the best test available to do this is called a “quantitative viral outgrowth assay,” or Q-VOA.

The new test that Gupta’s team developed is faster, less labour intensive, and less expensive, according to the study published in the journal Nature Medicine.

Called TZA, it works by detecting a gene that is turned on only when replicating HIV is present, thereby flagging the virus for technicians to quantify.

NewsGram brings to you current foreign news from all over the world.

It also requires a much smaller volume of blood, the study said.

“Using this test, we demonstrated that asymptomatic patients on antiretroviral therapy carry a much larger HIV reservoir than previous estimates — as much as 70 times what the Q-VOA test was detecting,” Gupta said. (IANS)


Popular

IANS

iPadOS 15 is Helping Millions Of Kids, Professionals Navigate Covid

As millions of students and professionals globally, including India, go back to learning and work from home amid the Covid wave triggered by the Omicron variant, the focus is back on devices that can boost their productivity and creativity at home and help them sail through the period. The all-new iPadOS 15 has brought in some fresh features to help kids navigate the crisis.

Take advantage of Quick Note, a fast and easy way to take notes anywhere outside the app, and you can even add links from apps and websites to provide context. You can simply start one by swiping up from the bottom right corner of the display. In iPadOS 15.2, you can also access Quick Note with a swipe from the lower left or lower right corner of the screen.

Keep Reading Show less
Unsplash

For the first time in independent India, now a postgraduate course in Hindu Dharma is included at the Benares Hindu University.

By Maria Wirth

Things are finally changing for the better for Hindu Dharma. For too long, many educated Indians, including the first Prime Minister Jawahar Nehru, had accepted the biased view of the British that Hinduism is inferior to the Abrahamic religions, without realizing, that this was a clever strategy to hide the fact that Christianity and Islam are based on a ‘must-belief’ story and Hinduism in contrast, is based on verifiable insights of the Vedas and a genuine enquiry into the truth.

For the first time in independent India, now a postgraduate course in Hindu Dharma is included at the Benares Hindu University. It reminded me that already almost one year ago, a centre to study the practice and philosophy of Nath Panth was established at Deen Dayal Upadhyaya Gorakhpur University by Yogi Adityanath, who himself is a Nath Yogi and the Mahant of Gorakhpur Mutt, apart from being the Chief Minister of Uttar Pradesh. A conference was held in March 2021, to which I contributed the following thoughts:

Keep Reading Show less
IANS

According to the family, the boy went missing in 2012.

He was 18 years old when he went missing from his home in the Mahmadpur village in Farrukhabad district. Brajpal returned to his house on Friday after more than ten years and his overjoyed parents could not believe their eyes. But a rival family informed the police as Brajpal's family had filed a kidnapping case against them. The police soon came and took away Brajpal for questioning.

According to the family, the boy went missing in 2012. His parents looked for him for nearly two years, and later approached the local police. It was when the local police allegedly refused to register their FIR, they went to the court and got an FIR registered at the Merapur police station against their neighbours, accusing them of kidnapping their son, following a land dispute.

missing signage Brajpal returned to his house on Friday after more than ten years | Unsplash

Keep reading... Show less