Never miss a story

Get subscribed to our newsletter


×
The researchers used a number of cell lines that represented possible SARS-CoV-2 infection targets in humans. Pexels

A team of researchers has found that three commonly used antiviral and antimalarial drugs are effective in vitro at preventing replication of SARS-CoV-2, the virus that causes Covid-19.

The study, published in the journal ACS Omega, looked at three antiviral drugs that have proven effective against Ebola and the Marburg virus — tilorone, quinacrine, and pyronaridine.


Follow NewsGram on Twitter to stay updated about the World news.

“We were looking for compounds that could block the entry of the virus into the cell,” said researcher Anna Puhl from the University of North Carolina in the US.


The research examined three antiviral drugs that have been shown to be effective against Ebola and the Marburg virus. Pixabay

“We chose these compounds because we know that other antivirals which successfully act against Ebola are also effective inhibitors of SARS-CoV-2,” Puhl added.

For the study, the compounds were tested in vitro against SARS-CoV-2, as well as against a common cold virus (HCV 229E) and murine hepatitis virus (MHV).

The researchers utilized a variety of cell lines that represented potential targets for SARS-CoV-2 infection in the human body. They infected the cell lines with the different viruses and then looked at how well the compounds prevented viral replication in the cells.

The team found that the results were mixed, with the compounds’ effectiveness depending upon whether they were used in human-derived cell lines versus monkey-derived cell lines, known as Vero cell lines.

ALSO READ: People Who Recieve Flu Shot Less Likely To Test COVID-19 Positive: Study

“In the human-derived cell lines, we found that all three compounds worked similarly to remdesivir, which is currently being used to treat Covid-19,” the researchers said.

The next steps for the research include testing the compounds’ effectiveness in a mouse model and further work on understanding how they inhibit viral replication. (IANS/KB)


Popular

Unsplash

Meta-owned WhatsApp on Monday announced an incubator programme in India.

Meta-owned WhatsApp on Monday announced an incubator programme in India that will select 10 organisations and help them build digital solutions to tackle critical health issues.

Called the WhatsApp Incubator Programme (WIP), the initiative aims to facilitate positive and measurable health outcomes at scale by leveraging the WhatsApp Business Platform.

Keep Reading Show less
Unsplash

India has to define its stand and negotiate its international policy keeping in view the nation's best interests of the long run.

By D.C. Pathak

Advent of Biden Presidency with its resonating calls of 'America is back', 'we will repair our alliances' and 'will engage with the world once again' on one hand and the rise of President Xi Jinping with a stronger hold on China after the Plenary session of the 19th Central Committee of CPC, on the other, have got strategic analysts to examine if a new Cold War was already on the horizon.

Keep Reading Show less
Unsplash

Digital becomes more popular and companies expand their D2C (direct-to-consumer) connections

Smartphone companies which have strong consumer pull now face most of the reputation issues caused by infringement of their brands in the digital space, according to a new report.

There are three main techniques pertaining to brand infringement —fake gratification, fake presence and fake representation.

According to Faisal Kawoosa, founder and chief analyst, Techarc, as digital becomes mainstream and brands increase their D2C (direct-to-consumer) engagements, they need to proactively police the digital space to hunt for any infringement cases.

Follow NewsGram on Twitter to stay updated about the World news.

"The first thing brands need to do is to come out of denial mode and create a common synergy between marketing, ecommerce, IT and digital teams," he said in the Brand Reputation Index (BRIX) report.

In fake gratification, scammers infringe any brand's identity by offering fake coupons, rewards, schemes, and discounts. This is the easiest trap for consumers who are searching for best deals when they decide about buying a smartphone of their interest.

Keep reading... Show less