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In the experiments, rats were trained to drink alcohol in a way that mimics human binge-drinking behaviour. Pixabay

It is now possible to use gene therapy in the brain to not only treat binge drinking but other substance abuse, neurological diseases and mental illnesses.

Researchers at the University at Buffalo have found a way to change alcohol drinking behaviour in rodents, using the emerging technique of optogenetics – using light to stimulate neurons.


In the experiments, rats were trained to drink alcohol in a way that mimics human binge-drinking behaviour.

“By stimulating certain dopamine neurons in a precise pattern, resulting in low but prolonged levels of dopamine release, we could prevent the rats from binging. The rats just flat out stopped drinking,” said Caroline E. Bass, assistant professor of pharmacology and toxicology in the UB School of Medicine and Biomedical Sciences.

Interestingly, the rodents continued to avoid alcohol even after the stimulation of neurons ended, Bass added.


Representational image. Pixabay

The researchers activated the dopamine neurons through a type of deep brain stimulation using a new technique called optogenetics.

“Optogenetics allows you to stimulate only one type of neuron at a time,” said the study published in the journal Frontiers in Neuroscience.

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“The results have application not only in understanding and treating alcohol-drinking behaviours in humans, but also in many devastating mental illnesses and neurological diseases that have a dopamine component,” said Bass.

The findings are the first to demonstrate a causal relationship between the release of dopamine in the brain and drinking behaviours of animals. (IANS)


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Rihanna was summoned from her seat to accept the honour, with the Prime Minister.

Singer Rihanna was honoured by Prime Minister Mia Mottley at an event which marked Barbados's new status as a republic, which was attended by Prince Charles. Addressing the pop star by her real name, the PM said: "Robyn Rihanna Fenty tomorrow morning shall have conferred upon her the order of national hero of Barbados."

Rihanna was then summoned from her seat to accept the honor, with the Prime Minister managing to rouse a laugh from the singer when she referenced her 2012 hit 'Diamonds', reports femalefirst.co.uk. She added: "On behalf of a grateful nation, but an even prouder people, we therefore present to you, the designee, for the national hero of Barbados." "And to accept on behalf of a grateful nation - you can come my dear - ambassador Robyn Rihanna Fenty, may you continue to shine like a diamond and bring honor to your nation." Rihanna, who was born in the St Michael parish of Barbados, found fame in 2005 after being spotted by a record producer and has since gone on to become one of the most successful female artists of all time with sales of over 250 million and recently reached billionaire status through her Fenty beauty brand.

The Prime Minister continued in her speech: "Commanding the imagination of the world through the pursuit of excellence, her creativity, her discipline, and above all else, her extraordinary commitment to the land of her birth. "Having satisfied that, Ambassador Robyn Rihanna Fenty has given service to Barbados which has been exemplified by visionary and pioneering leadership, extraordinary achievement and the attaining of the highest excellence to the Government of Barbados." It comes after a historic move for Barbados, which has become a republic after almost 400 years and welcomes its first president, Sandra Mason, after removing Queen Elizabeth as head of state. (IANS/ MBI)


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